Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Robin Vuilleumier"'
Publikováno v:
eLife, Vol 5 (2016)
Tight regulation of signalling activity is crucial for proper tissue patterning and growth. Here we investigate the function of Pentagone (Pent), a secreted protein that acts in a regulatory feedback during establishment and maintenance of BMP/Dpp mo
Externí odkaz:
https://doaj.org/article/7d2bc2d31c004b9b951debbc3f4f9f3e
Autor:
Robin Vuilleumier, Mo Miao, Sonia Medina-Giro, Clara-Maria Ell, Stephane Flibotte, Tianshun Lian, Grant Kauwe, Annie Collins, Sophia Ly, George Pyrowolakis, A Pejmun Haghighi, Douglas W Allan
Publikováno v:
Nucleic acids research. 50(17)
Retrograde bone morphogenetic protein (BMP) signaling at the Drosophila neuromuscular junction (NMJ) has served as a paradigm to study TGF-β-dependent synaptic function and maturation. Yet, how retrograde BMP signaling transcriptionally regulates th
Autor:
Alisa Fuchs, Robin Vuilleumier, Tianshun Lian, Zaynah N Khan, George Pyrowolakis, Douglas W. Allan, Stephane Flibotte
Publikováno v:
Nucleic Acids Research
Retrograde Bone Morphogenetic Protein (BMP) signaling in neurons is essential for the differentiation and synaptic function of many neuronal subtypes. BMP signaling regulates these processes via Smad transcription factor activity, yet the scope and n
Autor:
Ola Söderberg, George Pyrowolakis, Carl-Henrik Heldin, Kalliopi Tzavlaki, Robin Vuilleumier, Karolina Edlund, Patrick Micke, Yukihide Watanabe, Johan Botling, Kaoru Kahata, Anita Morén, Agata Zieba, Erna Raja, Iryna Voytyuk, Aristidis Moustakas
Publikováno v:
Oncotarget
The protein kinase LKB1 regulates cell metabolism and growth and is implicated in intestinal and lung cancer. Bone morphogenetic protein (BMP) signaling regulates cell differentiation during development and tissue homeostasis. We demonstrate that LKB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f1eeb68bb14122ac77a6c901801673f
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-278888
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-278888
Autor:
Matthias Hammerschmidt, Alexander Springhorn, Lucy J. Patterson, George Pyrowolakis, Markus Affolter, Stefanie Koidl, Robin Vuilleumier
Publikováno v:
Nature Cell Biology. 12:611-617
In many instances during development, morphogens specify cell fates by forming concentration gradients. In the Drosophila melanogaster wing imaginal disc, Decapentaplegic (Dpp), a bone morphogenetic protein (BMP), functions as a long-range morphogen
Publikováno v:
European Journal of Neuroscience. 25:3047-3057
Melatonin biosynthesis from serotonin involves the sequential activation of the arylalkylamine N-acetyltransferase (AANAT) and hydroxyindole-O-methyltransferase (HIOMT). Photoperiod synchronizes a daily rhythm in pineal and retinal melatonin secretio
Publikováno v:
Journal de la Société de Biologie. 201:13-20
La melatonine est l'hormone donneuse de temps chez les Vertebres. Par la dynamique de sa production nycthemerale et saisonniere, elle assure la synchronisation de fonctions physiologiques et de comportements sur des periodicites naturelles. Chez les
Autor:
Laurence Besseau, Yoav Gothilf, Aurélien Piparelli, Gilles Boeuf, David C. Klein, Jack Falcón, Walter G. Gehring, Robin Vuilleumier
Publikováno v:
Endocrinology. 147:2273-2279
The issue of what starts the circadian clock ticking was addressed by studying the developmental appearance of the daily rhythm in the expression of two genes in the zebrafish pineal gland that are part of the circadian clock system. One encodes the
Publikováno v:
Fly. 5(3)
Orchestration of spatial organization by signaling gradients - morphogen gradients - is a fundamental principle in animal development. Despite their importance in tissue patterning and growth, the exact mechanisms underlying the establishment and mai