Výsledky vyhledávání - "Robin Sculthorpe"

Akademický článek

Vitamin C Intravenous Treatment In the Setting of Atrial Fibrillation Ablation: Results From the Randomized, Double‐Blinded, Placebo‐Controlled CITRIS‐AF Pilot Study

Autor: Cory R. Trankle, Laura Puckett, Theresa Swift‐Scanlan, Christine DeWilde, Anna Priday, Robin Sculthorpe, Kenneth A. Ellenbogen, Alpha Fowler, Jayanthi N. Koneru

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 3 (2020)

Background Catheter ablation is an effective treatment for atrial fibrillation (AF), but high levels of post‐procedure inflammation predict adverse clinical events. Ascorbic acid (AA) has shown promise in reducing inflammation but is untested in th

Externí odkaz: https://doaj.org/article/9fd8c62979764d2faeeb372cd9053dc2

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Comparison of safety and biological efficacy of anakinra (Kineret ®) dispensed in polycarbonate plastic versusborosilicate glass syringes: a patient-level analysis of VCUART2 and VCUART3 clinical trials

Autor: Azita Talasaz, Robin Sculthorpe, Mary Pak, Michael Lipinski, Charlotte Roberts, Roshanak Markley, Cory Trankle, Justin M Canada, George F Wohlford, Michele Golino, Dave L Dixon, Benjamin Van Tassell, Antonio Abbate

Publikováno v: Journal of Pharmacology and Experimental Therapeutics. :JPET-AR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9104e8426dc03ba747f780aa83df6f73
https://doi.org/10.1124/jpet.122.001404

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Vitamin C Intravenous Treatment In the Setting of Atrial Fibrillation Ablation: Results From the Randomized, Double-Blinded, Placebo-Controlled CITRIS-AF Pilot Study

Autor: Alpha A. Fowler, Cory R. Trankle, Theresa Swift-Scanlan, Anna Priday, Kenneth A. Ellenbogen, Jayanthi N. Koneru, Robin Sculthorpe, Laura Puckett, Christine DeWilde

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

Background Catheter ablation is an effective treatment for atrial fibrillation ( AF ), but high levels of post‐procedure inflammation predict adverse clinical events. Ascorbic acid ( AA ) has shown promise in reducing inflammation but is untested i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8fc4dc0a275000c6082b791a152490
https://pubmed.ncbi.nlm.nih.gov/32013700

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Rationale and design of the Virginia Commonwealth University-Anakinra Remodeling Trial-3 (VCU-ART3): A randomized, placebo-controlled, double-blinded, multicenter study

Publikováno v: Clinical Cardiology. 41:1004-1008

There is clear association between the intensity of the acute inflammatory response during acute myocardial infarction (AMI) and adverse prognosis after AMI. Interleukin‐1 (IL‐1) is a pro‐inflammatory cytokine released during AMI and involved i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb0edb5fe726e0884d995619683efb7
https://doi.org/10.1002/clc.22988

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Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure: The CITRIS-ALI Randomized Clinical Trial

Publikováno v: JAMA. 322(13)

Importance Experimental data suggest that intravenous vitamin C may attenuate inflammation and vascular injury associated with sepsis and acute respiratory distress syndrome (ARDS). Objective To determine the effect of intravenous vitamin C infusion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cd451ce40b8473e9d997bd87f39a847
https://pubmed.ncbi.nlm.nih.gov/32096842

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Interleukin-1 Blockade in Recently Decompensated Systolic Heart Failure: Results from the REcently Decompensated Heart failure Anakinra Response Trial (REDHART)

Background An enhanced inflammatory response predicts worse outcomes in heart failure (HF). We hypothesized that administration of IL-1 (interleukin-1) receptor antagonist (anakinra) could inhibit the inflammatory response and improve peak aerobic ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a50acc0867c48c513881df27f84f3de
https://europepmc.org/articles/PMC5699505/

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VITAMIN C INTRAVENOUS TREATMENT IN THE SETTING OF ATRIAL FIBRILLATION ABLATION: RESULTS FROM THE RANDOMIZED, DOUBLE-BLINDED, PLACEBO-CONTROLLED CITRIS-AF STUDY

Autor: Laura Puckett, Robin Sculthorpe, Theresa Swift-Scanlan, Christine DeWilde, Jayanthi N. Koneru, Kenneth A. Ellenbogen, Alpha A. Fowler, Cory R. Trankle

Publikováno v: Journal of the American College of Cardiology. 73:363

Catheter ablation is an effective treatment for atrial fibrillation (AF), but high levels of post-procedure inflammation predict adverse clinical events. Ascorbic acid (AA) has shown promise in reducing sterile inflammation but is untested in this po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bcc43d1a8d8e4332f6cbe32dbca8d1c5
https://doi.org/10.1016/s0735-1097(19)30971-4

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Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis

Autor: Terri Larus, Donald F. Brophy, Alpha A. Fowler, Christine DeWilde, Seema Gupta, Don Farthing, Erika J. Martin, Robin Sculthorpe, Christine A. Farthing, Ramesh Natarajan, Aamer Syed, Bernard J. Fisher, Shelley Knowlson

Publikováno v: Journal of Translational Medicine

Parenterally administered ascorbic acid modulates sepsis-induced inflammation and coagulation in experimental animal models. The objective of this randomized, double-blind, placebo-controlled, phase I trial was to determine the safety of intravenousl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d21b482ab4b13b02b9a7f153c707783
https://doi.org/10.1186/1479-5876-12-32

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