Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Robin P Love"'
Publikováno v:
Frontiers in Microbiology, Vol 5 (2014)
The APOBEC3 restriction factors are a family of deoxycytidine deaminases that are able to suppress replication of viruses with a single-stranded DNA intermediate by inducing mutagenesis and functional inactivation of the virus. Of the seven human APO
Externí odkaz:
https://doaj.org/article/3b6401545eba4ba0988e562b5181728c
Publikováno v:
PLoS Pathogens, Vol 10, Iss 3, p e1004024 (2014)
The APOBEC3 deoxycytidine deaminase family functions as host restriction factors that can block replication of Vif (virus infectivity factor) deficient HIV-1 virions to differing degrees by deaminating cytosines to uracils in single-stranded (-)HIV-1
Externí odkaz:
https://doaj.org/article/c34fdc20b038454bb188023ac7900466
Autor:
Nazanin Mohammadzadeh, Robin P. Love, Richard Gibson, Eric J. Arts, Art F.Y. Poon, Linda Chelico
Publikováno v:
Heliyon, Vol 5, Iss 4, Pp e01498- (2019)
The APOBEC3 enzymes can induce mutagenesis of HIV-1 proviral DNA through the deamination of cytosine. HIV-1 overcomes this restriction through the viral protein Vif that induces APOBEC3 proteasomal degradation. Within this dynamic host-pathogen relat
Externí odkaz:
https://doaj.org/article/f9efa491831749fb83244e02b671ce2d
Autor:
Robin P, Love, Billie-Jo, Hardy, Courtney, Heffernan, Amber, Heyd, Melissa, Cardinal-Grant, Lori, Sparling, Bonnie, Healy, Janet, Smylie, Richard, Long
Publikováno v:
Health and human rights. 24(1)
Indigenous rights to self-determination and data sovereignty support Indigenous-led data governance, which, when adequately resourced, can act as a catalyst for Indigenous-led strategic planning and decision-making in public health research and progr
Publikováno v:
Dermatologic Surgery. 46:1705-1711
Background Follicular unit excision (FUE) is used to harvest follicular units for hair transplantation using trephine punches. The characteristics of FUE punches can impact the success of this technique; thus, many innovative punch designs and device
Autor:
Madison B. Adolph, Robin P. Love, Nazanin Mohammadzadeh, Linda Chelico, Louis M. Mansky, Yumeng Z McDaniel, Dake Wang
Publikováno v:
Nucleic Acids Research
The human apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3 (APOBEC3, A3) family member proteins can deaminate cytosines in single-strand (ss) DNA, which restricts human immunodeficiency virus type 1 (HIV-1), retrotransposons, and ot
Autor:
Linda Chelico, Brett Zirkle, Shu-Xing Li, Robin P. Love, Fumiaki Ito, Amit Gaba, Hanjing Yang, Maocai Yan, Aaron Wolfe, Xiaojiang S. Chen, Nazanin Mohammadzadeh
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
APOBEC3G, a member of the double-domain cytidine deaminase (CD) APOBEC, binds RNA to package into virions and restrict HIV-1 through deamination-dependent or deamination-independent inhibition. Mainly due to lack of a full-length double-domain APOBEC
Autor:
Nazanin Mohammadzadeh, Robin P. Love, Tyson B. Follack, Linda Chelico, Stephen E. Sanche, Kris Stewart
Publikováno v:
Virology. 527:21-31
The APOBEC3 enzyme family are host restriction factors that induce mutagenesis of HIV-1 proviral genomes through the deamination of cytosine to form uracil in nascent single-stranded (-)DNA. HIV-1 suppresses APOBEC3 activity through the HIV-1 protein
Publikováno v:
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. 46(8)
Background Follicular unit excision (FUE) and follicular unit transplantation using strip surgery (FUT) are the dominant graft harvest methods in hair transplantation. The increase in the demand for FUE has reignited the debate of the relative superi
Publikováno v:
Skinmed. 17(4)
Follicular unit excision (FUE) requires the careful excision of hair-bearing follicular units. The follicle can only be detached from the skin once the epidermis, dermis, and subcutaneous tissues are cut, and each layer requires a different amount of