Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Robin O'Connor-Semmes"'
Autor:
Robert Dobbins, Elizabeth K. Hussey, Robin O’Connor-Semmes, Susan Andrews, Wenli Tao, William O. Wilkison, Bentley Cheatham, Katare Sagar, Barkate Hanmant
Publikováno v:
BMC Pharmacology and Toxicology, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background Patients with type 2 diabetes mellitus (T2DM) are characterized by an elevated glycemic index and are at a higher risk for complications such as cardiovascular disease, nephropathy, retinopathy and peripheral neuropathy. Normaliza
Externí odkaz:
https://doaj.org/article/ee619324b38a44d88d714cf84257f4f3
Autor:
Barkate Hanmant, Robert Dobbins, Susan Andrews, Bentley Cheatham, Robin O'Connor-Semmes, Elizabeth Hussey, Katare Sagar, Wenli Tao, William O. Wilkison
Publikováno v:
BMC Pharmacology and Toxicology, Vol 22, Iss 1, Pp 1-11 (2021)
BMC Pharmacology & Toxicology
BMC Pharmacology & Toxicology
Background Patients with type 2 diabetes mellitus (T2DM) are characterized by an elevated glycemic index and are at a higher risk for complications such as cardiovascular disease, nephropathy, retinopathy and peripheral neuropathy. Normalization of g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc3a4e5498b39d7a1a70581e976409b
https://doaj.org/article/ee619324b38a44d88d714cf84257f4f3
https://doaj.org/article/ee619324b38a44d88d714cf84257f4f3
Autor:
Alexander Drilon, Martijn P. Lolkema, Hui K Gan, Robert C. Gagnon, Gopinath Ganji, Carla L.M. Van Herpen, Ignacio Garrido-Laguna, Bruce A. Hug, Jason D. Lickliter, Robin O'Connor-Semmes, Jan H.M. Schellens, Catherine E. Ellis, Christopher Matheny, Michael Millward, Mathilde Jalving, Lihua Tang
Publikováno v:
The Oncologist, 26(10), e1844-e1853. ALPHAMED PRESS
The Oncologist
Oncologist, 26, 10, pp. e1844-e1853
Oncologist, 26, e1844-e1853
The Oncologist
Oncologist, 26, 10, pp. e1844-e1853
Oncologist, 26, e1844-e1853
Background GSK2849330, an anti‐HER3 monoclonal antibody that blocks HER3/Neuregulin 1 (NRG1) signaling in cancer cells, is engineered for enhanced antibody‐dependent cellular cytotoxicity and complement‐dependent cytotoxicity. This phase I, fir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca765b079fda30d6838b7dbd1c38708d
https://hdl.handle.net/2066/244559
https://hdl.handle.net/2066/244559
Autor:
Peter D. Gorycki, Kristen E. Pannullo, Melisa Cooper, Robin O'Connor-Semmes, Beth Ann Reedy, Kimberley Hacquoil, Sepehr Shakib, Adeline Verticelli
Publikováno v:
Clinical Pharmacology in Drug Development. 8:234-245
Rearranged during transfection (RET), a neuronal growth factor receptor tyrosine kinase, regulates the development of the sympathetic, parasympathetic, motor, and sensory neurons in the enteric nervous system. GSK3179106 is a RET kinase inhibitor tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596390355047b625fe67f7430123fd73
https://doi.org/10.1002/cpdd.600
https://doi.org/10.1002/cpdd.600
Autor:
Robin O'Connor-Semmes, Adeline Verticelli, Kimberley Hacquoil, Beth Ann Reedy, Peter D. Gorycki, Angela Molga
Publikováno v:
Clinical pharmacology in drug developmentReferences. 10(4)
Rearranged during transfection (RET), a neuronal growth factor receptor tyrosine kinase, regulates the development of sympathetic, parasympathetic, motor, and sensory neurons in the enteric nervous system. The intended site of action for GSK3352589 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a808c60983edfc3909439ddd99256616
https://pubmed.ncbi.nlm.nih.gov/33606922
https://pubmed.ncbi.nlm.nih.gov/33606922
Autor:
S.W. Johnny Lau, Robin O'Connor-Semmes, Donald Heald, Jan-Frederik Schlender, Patricia W. Slattum
Publikováno v:
Clinical pharmacology and therapeutics. 107(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c6ae5d77ae8a294e4f24dc842abb014
https://pubmed.ncbi.nlm.nih.gov/31667834
https://pubmed.ncbi.nlm.nih.gov/31667834