Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Robin Mogg"'
Autor:
David G. Pfister, Robert I. Haddad, Francis P. Worden, Jared Weiss, Ranee Mehra, Laura Q. M. Chow, Stephen V. Liu, Hyunseok Kang, Nabil F. Saba, Lori J. Wirth, Ammar Sukari, Erminia Massarelli, Mark Ayers, Andrew Albright, Andrea L. Webber, Robin Mogg, Jared Lunceford, Lingkang Huang, Razvan Cristescu, Jonathan Cheng, Tanguy Y. Seiwert, Joshua M. Bauml
Publikováno v:
Cancer Medicine, Vol 12, Iss 6, Pp 6603-6614 (2023)
Abstract Background We performed an integrated biomarker evaluation in pembrolizumab‐treated patients with R/M HNSCC enrolled in KEYNOTE‐012 or KEYNOTE‐055. The relationship between biomarkers and HPV status was explored. Methods We evaluated P
Externí odkaz:
https://doaj.org/article/41ead9902e374b769caeb779819059f4
Publikováno v:
Contemporary Clinical Trials Communications, Vol 34, Iss , Pp 101100- (2023)
A number of principal investigators may have limited access to biostatisticians, a lack of biostatistical training, or no requirement to complete a timely statistical analysis plan (SAP). SAPs completed early will identify design or implementation we
Externí odkaz:
https://doaj.org/article/251bed2e89f74fabaceac58db1084930
Autor:
Randolph P. Matthews, Wendy Ankrom, Evan Friedman, Deanne Jackson Rudd, Yang Liu, Robin Mogg, Deborah Panebianco, Inge De Lepeleire, Magdalena Petkova, Jay A. Grobler, Selwyn Aubrey Stoch, Marian Iwamoto
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 5, Pp 1935-1944 (2021)
Abstract Islatravir (MK‐8591) is a nucleoside analogue in development for the treatment and prevention of HIV‐1. Two phase 1 trials were conducted during initial evaluation of islatravir: rising single doses (Study 1) and rising multiple doses (S
Externí odkaz:
https://doaj.org/article/6f26b820a53d4b0c9215bb7d0664b680
Autor:
Alberto L. Garcia-Basteiro, Richard G. White, Dereck Tait, Alexander C. Schmidt, Molebogeng X. Rangaka, Matthew Quaife, Elisa Nemes, Robin Mogg, Philip C. Hill, Rebecca C. Harris, Willem A. Hanekom, Mike Frick, Andrew Fiore-Gartland, Tom Evans, Alemnew F. Dagnew, Gavin Churchyard, Frank Cobelens, Marcel A. Behr, Mark Hatherill
Publikováno v:
European Respiratory Review, Vol 31, Iss 164 (2022)
Tuberculosis (TB) remains a leading infectious cause of death worldwide and the coronavirus disease 2019 pandemic has negatively impacted the global TB burden of disease indicators. If the targets of TB mortality and incidence reduction set by the in
Externí odkaz:
https://doaj.org/article/87396fc05bac435a828bd8864008890f
Autor:
Makoto Tahara, Ranee Mehra, Kei Muro, Bhumsuk Keam, Mark Ayers, Robin Mogg, Razvan Cristescu, Jared Lunceford, Andrew Albright, Jonathan Cheng, Barbara Burtness, Shilpa Gupta, Hyunseok Kang, Laura Q M Chow, Lingkang Huang, Joseph P Eder, Jared Weiss, Robert I Haddad, Tanguy Y Seiwert, Iris Gluck
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
Background To characterize genomic determinants of response to pembrolizumab in recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) in the KEYNOTE-012 study.Methods Associations between biomarkers (tumor mutational burden (TMB),
Externí odkaz:
https://doaj.org/article/05117fe7797641be9fc4bdea2cd680a3
Autor:
Ahilanandan Dushianthan, Howard Clark, Jens Madsen, Robin Mogg, Lewis Matthews, Lee Berry, Jorge Bernardino de la Serna, James Batchelor, David Brealey, Tracy Hussell, Joanna Porter, Ratko Djukanovic, Martin Feelisch, Anthony Postle, Michael P. W. Grocott
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-3 (2020)
Abstract Objectives SARS-Cov-2 virus preferentially binds to the Angiotensin Converting Enzyme 2 (ACE2) on alveolar epithelial type II cells, initiating an inflammatory response and tissue damage which may impair surfactant synthesis contributing to
Externí odkaz:
https://doaj.org/article/e06ae409470d45d1addb648b7e58875c
Autor:
David G. Pfister, Robert I. Haddad, Francis P. Worden, Jared Weiss, Ranee Mehra, Laura Q. M. Chow, Stephen V. Liu, Hyunseok Kang, Nabil F. Saba, Lori J. Wirth, Ammar Sukari, Erminia Massarelli, Mark Ayers, Andrew Albright, Andrea L. Webber, Robin Mogg, Jared Lunceford, Lingkang Huang, Razvan Cristescu, Jonathan Cheng, Tanguy Y. Seiwert, Joshua M. Bauml
Publikováno v:
Cancer medicineREFERENCES.
We performed an integrated biomarker evaluation in pembrolizumab-treated patients with R/M HNSCC enrolled in KEYNOTE-012 or KEYNOTE-055. The relationship between biomarkers and HPV status was explored.We evaluated PD-L1 (combined positive score [CPS]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d116a13a91651a97a8f30132dae54fff
https://pubmed.ncbi.nlm.nih.gov/36479637
https://pubmed.ncbi.nlm.nih.gov/36479637
Autor:
Sue Jane Wang, Suzanne Hendrix, Klaus Romero, Aloka Chakravarty, John-Michael Sauer, Samuel P. Dickson, Lisa M. McShane, Robin Mogg
Publikováno v:
Biomarkers in Medicine
Qualification of a biomarker for use in a medical product development program requires a statistical strategy that aligns available evidence with the proposed context of use (COU), identifies any data gaps to be filled and plans any additional resear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ada180c1e3ade7afb533f79ed6c4acc
http://europepmc.org/articles/PMC8293027
http://europepmc.org/articles/PMC8293027
Autor:
Maurine D. Miner, Mark Hatherill, Vidya Mave, Judith Currier, Joseph Eron, Glenda E. Gray, Sharon Nachman, Peter Kim, Sarah Read, Richard White, Anneke Hessling, Frank Cobelens, Sheral Patel, Mike Frick, Theodore Bailey, Robert Seder, Joanne Flynn, Jyothi Rengarajan, Deepak Kaushal, Willem Hanekom, Alexander Schmidt, Thomas Scriba, Elisa Nemes, Erica Andersen-Nissen, Alan Landay, Susan Dorman, Grace Aldrovandi, Lisa M. Cranmer, Cheryl Day, Lele Rangaka, Alberto Garcia-Basteiro, Andrew Fiore-Gartland, Robin Mogg, James G. Kublin, Amita Gupta, Gavin Churchyard
Many new TB vaccine candidates in the development pipeline need to be studied in people with HIV. People with HIV are at high risk of developing Mycobacterium tuberculosis (Mtb) infection and TB disease and tend to develop less robust vaccine induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76fb3a5fd77fda8454cbd2bdd99aa27b
https://doi.org/10.21203/rs.3.rs-1605760/v1
https://doi.org/10.21203/rs.3.rs-1605760/v1
Autor:
Maurine D Miner, Mark Hatherill, Vidya Mave, Glenda E Gray, Sharon Nachman, Sarah W Read, Richard G White, Anneke Hesseling, Frank Cobelens, Sheral Patel, Mike Frick, Theodore Bailey, Robert Seder, Joanne Flynn, Jyothi Rengarajan, Deepak Kaushal, Willem Hanekom, Alexander C Schmidt, Thomas J Scriba, Elisa Nemes, Erica Andersen-Nissen, Alan Landay, Susan E Dorman, Grace Aldrovandi, Lisa M Cranmer, Cheryl L Day, Alberto L Garcia-Basteiro, Andrew Fiore-Gartland, Robin Mogg, James G Kublin, Amita Gupta, Gavin Churchyard
Publikováno v:
The lancet. HIV. 9(11)
New tuberculosis vaccine candidates that are in the development pipeline need to be studied in people with HIV, who are at high risk of acquiring Mycobacterium tuberculosis infection and tuberculosis disease and tend to develop less robust vaccine-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90d26ce98f9fb2a6dfce9deddf9930fd
https://pubmed.ncbi.nlm.nih.gov/36372080
https://pubmed.ncbi.nlm.nih.gov/36372080