Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Robin Mjelle"'
Autor:
Robin Mjelle, Are K. Kristensen, Tora S. Solheim, Ganna S. Westvik, Hege Elvebakken, Eva Hofsli
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-9 (2024)
Abstract Metastatic colorectal cancer (mCRC) presents significant challenges in clinical management due to its heterogeneity and variable response to treatment. In this study, we conducted comprehensive small RNA (sRNA) sequencing analyses to identif
Externí odkaz:
https://doaj.org/article/416e2b51900c496089e51281a8b66919
Autor:
Synne Stokke Tryggestad, Ingrid Aass Roseth, Kristin Roseth Aass, Nadia Elise Helene Ørning, Robin Mjelle, Hanne Hella, Therese Standal
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Infections are common in plasma cell cancer multiple myeloma (MM) due to disease-related immune deficiencies and cancer treatment. Myeloma cells express Toll-like receptors (TLRs), and TLR activation has been shown to induce proliferative and pro-sur
Externí odkaz:
https://doaj.org/article/8cb542355cd549edbe69732e21977ed3
Autor:
Therese Haugdahl Nøst, Anne Heidi Skogholt, Ilona Urbarova, Robin Mjelle, Erna‐Elise Paulsen, Tom Dønnem, Sigve Andersen, Maria Markaki, Oluf Dimitri Røe, Mikael Johansson, Mattias Johansson, Bjørn Henning Grønberg, Torkjel Manning Sandanger, Pål Sætrom
Publikováno v:
Molecular Oncology, Vol 17, Iss 2, Pp 312-327 (2023)
Lung cancer (LC) incidence is increasing globally and altered levels of microRNAs (miRNAs) in blood may contribute to identification of individuals with LC. We identified miRNAs differentially expressed in peripheral blood at LC diagnosis and evaluat
Externí odkaz:
https://doaj.org/article/f11aa83983e74d5985fd3b02450edf55
Autor:
Kristin Roseth Aass, Tonje Marie Vikene Nedal, Synne Stokke Tryggestad, Einar Haukås, Tobias S. Slørdahl, Anders Waage, Therese Standal, Robin Mjelle
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Multiple myeloma (MM) is an incurable cancer of terminally differentiated plasma cells that proliferate in the bone marrow. miRNAs are promising biomarkers for risk stratification in MM and several miRNAs are shown to have a function in dise
Externí odkaz:
https://doaj.org/article/ef4e64336d834f08bf2e9d4578ad27ee
Autor:
Kristin Roseth Aass, Synne Stokke Tryggestad, Robin Mjelle, Martin H. Kastnes, Tonje Marie Vikene Nedal, Kristine Misund, Therese Standal
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Multiple myeloma (MM) is a hematological cancer characterized by accumulation of malignant plasma cells in the bone marrow. The patients are immune suppressed and suffer from recurrent and chronic infections. Interleukin-32 is a non-conventional, pro
Externí odkaz:
https://doaj.org/article/ad856e22ff75450697d0815a497d6020
Autor:
Ioannis Konstantinidis, Pål Sætrom, Robin Mjelle, Artem V. Nedoluzhko, Diego Robledo, Jorge M. O. Fernandes
Publikováno v:
Epigenetics, Vol 15, Iss 10, Pp 1052-1067 (2020)
The historically recent domestication of fishes has been essential to meet the protein demands of a growing human population. Selection for traits of interest during domestication is a complex process whose epigenetic basis is poorly understood. Cyto
Externí odkaz:
https://doaj.org/article/8b5ace4e586146aaad9b43fb6fea1da0
Autor:
Kristin Roseth Aass, Robin Mjelle, Martin H. Kastnes, Synne S. Tryggestad, Luca M. van den Brink, Ingrid Aass Roseth, Marita Westhrin, Muhammad Zahoor, Siv H. Moen, Tonje M. Vikene Nedal, Glenn Buene, Kristine Misund, Anne-Marit Sponaas, Qianli Ma, Anders Sundan, Richard WJ. Groen, Tobias S. Slørdahl, Anders Waage, Therese Standal
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103605- (2022)
Summary: Interleukin-32 (IL-32) is a nonclassical cytokine expressed in cancers, inflammatory diseases, and infections. Its expression is regulated by two different oxygen sensing systems; HIF1α and cysteamine dioxygenase (ADO), indicating that IL-3
Externí odkaz:
https://doaj.org/article/f13877db61e44076b7c17265f09790b3
Autor:
Robin Mjelle, Simona O. Dima, Nicolae Bacalbasa, Konika Chawla, Andrei Sorop, Dana Cucu, Vlad Herlea, Pål Sætrom, Irinel Popescu
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-13 (2019)
Abstract Background The expression of microRNAs (miRNAs) is a promising prognostic and diagnostic tool in hepatocellular carcinoma (HCC). Here we performed small RNA sequencing (sRNA-seq) of tissue, serum and serum exosomes to investigate changes in
Externí odkaz:
https://doaj.org/article/a32e7ab77bf640d384bbe4802c0f87e3
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background MicroRNAs (miRNA) and other small RNAs are frequently dysregulated in cancer and are promising biomarkers for colon cancer. Here we profile human, virus and bacteria small RNAs in normal and tumor tissue from early stage colon can
Externí odkaz:
https://doaj.org/article/d487f9163df64c30b2479408a5594a52
Publikováno v:
iScience, Vol 23, Iss 5, Pp - (2020)
Summary: Understanding microbial communities' roles in human health and disease requires methods that accurately characterize the microbial composition and their activity and effects within human biological samples. We present sMETASeq (small RNA Met
Externí odkaz:
https://doaj.org/article/1165fb6c02ca4b87a7fd8f55eb274de0