Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Robin M. Meyers"'
Autor:
Elaine M. Oberlick, Matthew G. Rees, Brinton Seashore-Ludlow, Francisca Vazquez, Geoffrey M. Nelson, Neekesh V. Dharia, Barbara A. Weir, Aviad Tsherniak, Mahmoud Ghandi, John M. Krill-Burger, Robin M. Meyers, Xiaofeng Wang, Phil Montgomery, David E. Root, Jake M. Bieber, Sandi Radko, Jaime H. Cheah, C. Suk-Yee Hon, Alykhan F. Shamji, Paul A. Clemons, Peter J. Park, Michael A. Dyer, Todd R. Golub, Kimberly Stegmaier, William C. Hahn, Elizabeth A. Stewart, Stuart L. Schreiber, Charles W.M. Roberts
Publikováno v:
Cell Reports, Vol 28, Iss 9, Pp 2331-2344.e8 (2019)
Summary: Cancer is often seen as a disease of mutations and chromosomal abnormalities. However, some cancers, including pediatric rhabdoid tumors (RTs), lack recurrent alterations targetable by current drugs and need alternative, informed therapeutic
Externí odkaz:
https://doaj.org/article/92a087e67b0f487ba84b47b60011a6bf
Autor:
Ricardo de Matos Simoes, Ryosuke Shirasaki, Sondra L. Downey-Kopyscinski, Geoffrey M. Matthews, Benjamin G. Barwick, Vikas A. Gupta, Daphné Dupéré-Richer, Shizuka Yamano, Yiguo Hu, Michal Sheffer, Eugen Dhimolea, Olga Dashevsky, Sara Gandolfi, Kazuya Ishiguro, Robin M. Meyers, Jordan G. Bryan, Neekesh V. Dharia, Paul J. Hengeveld, Johanna B. Brüggenthies, Huihui Tang, Andrew J. Aguirre, Quinlan L. Sievers, Benjamin L. Ebert, Brian J. Glassner, Christopher J. Ott, James E. Bradner, Nicholas P. Kwiatkowski, Daniel Auclair, Joan Levy, Jonathan J. Keats, Richard W. J. Groen, Nathanael S. Gray, Aedin C. Culhane, James M. McFarland, Joshua M. Dempster, Jonathan D. Licht, Lawrence H. Boise, William C. Hahn, Francisca Vazquez, Aviad Tsherniak, Constantine S. Mitsiades
Publikováno v:
de Matos Simoes, R, Shirasaki, R, Downey-Kopyscinski, S L, Matthews, G M, Barwick, B G, Gupta, V A, Dupéré-Richer, D, Yamano, S, Hu, Y, Sheffer, M, Dhimolea, E, Dashevsky, O, Gandolfi, S, Ishiguro, K, Meyers, R M, Bryan, J G, Dharia, N V, Hengeveld, P J, Brüggenthies, J B, Tang, H, Aguirre, A J, Sievers, Q L, Ebert, B L, Glassner, B J, Ott, C J, Bradner, J E, Kwiatkowski, N P, Auclair, D, Levy, J, Keats, J J, Groen, R W J, Gray, N S, Culhane, A C, McFarland, J M, Dempster, J M, Licht, J D, Boise, L H, Hahn, W C, Vazquez, F, Tsherniak, A & Mitsiades, C S 2023, ' Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias ', Nature Cancer, vol. 4, no. 5, pp. 754-773 . https://doi.org/10.1038/s43018-023-00550-x
Nature Cancer, 4(5), 754-773. Nature Research
Nature Cancer, 4(5), 754-773. Nature Research
Clinical progress in multiple myeloma (MM), an incurable plasma cell (PC) neoplasia, has been driven by therapies that have limited applications beyond MM/PC neoplasias and do not target specific oncogenic mutations in MM. Instead, these agents targe
Autor:
Smarajit Mondal, Muthukumar Ramanathan, Weili Miao, Robin M. Meyers, Deepti Rao, Vanessa Lopez-Pajares, Zurab Siprashvili, David L. Reynolds, Douglas F. Porter, Ian Ferguson, Poornima Neela, Yang Zhao, Lindsey M. Meservey, Margaret Guo, Yen-Yu Yang, Lin Li, Yinsheng Wang, Paul A. Khavari
Publikováno v:
Nat Methods
DNA-protein interactions mediate physiologic gene regulation and may be altered by DNA variants linked to polygenic disease. To enhance the speed and signal-to-noise ratio (SNR) in the identification and quantification of proteins associated with spe
Autor:
William C. Hahn, Aviad Tsherniak, David E. Root, Matthew Meyerson, Todd R. Golub, Charles W. Roberts, Kimberly Stegmaier, Levi A. Garraway, Glenn S. Cowley, Gregory Kryukov, Coyin Oh, Andrew D. Cherniack, Amy Goodale, Yenarae Lee, Sasha Pantel, Guozhi Jiang, Levi D. Ali, Han Xu, Stanley Gill, Maria Kost-Alimova, Mihir B. Doshi, William F. Harrington, Gavin Ha, April Cook, Uri Ben-David, Cheng-Zhong Zhang, Francisca Vazquez, Barbara A. Weir, Robin M. Meyers, Andrew J. Aguirre
Supplementary Figure S1. Genome-scale CRISPR-Cas9 screening identifies a strong correlation between copy number and sensitivity to CRISPR-Cas9 genome editing. Supplementary Figure S2. Global summary of the relationship of CRISPR-Cas9 guide scores to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38a19689f343908709fb1c22c634cf7b
https://doi.org/10.1158/2159-8290.22531296
https://doi.org/10.1158/2159-8290.22531296
Autor:
William C. Hahn, Aviad Tsherniak, David E. Root, Matthew Meyerson, Todd R. Golub, Charles W. Roberts, Kimberly Stegmaier, Levi A. Garraway, Glenn S. Cowley, Gregory Kryukov, Coyin Oh, Andrew D. Cherniack, Amy Goodale, Yenarae Lee, Sasha Pantel, Guozhi Jiang, Levi D. Ali, Han Xu, Stanley Gill, Maria Kost-Alimova, Mihir B. Doshi, William F. Harrington, Gavin Ha, April Cook, Uri Ben-David, Cheng-Zhong Zhang, Francisca Vazquez, Barbara A. Weir, Robin M. Meyers, Andrew J. Aguirre
Sample Information: Table with cell line identities and relevant information for this manuscript.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e85aa9705ce87ea97e87829b5808053
https://doi.org/10.1158/2159-8290.22531287.v1
https://doi.org/10.1158/2159-8290.22531287.v1
Autor:
William C. Hahn, Aviad Tsherniak, David E. Root, Matthew Meyerson, Todd R. Golub, Charles W. Roberts, Kimberly Stegmaier, Levi A. Garraway, Glenn S. Cowley, Gregory Kryukov, Coyin Oh, Andrew D. Cherniack, Amy Goodale, Yenarae Lee, Sasha Pantel, Guozhi Jiang, Levi D. Ali, Han Xu, Stanley Gill, Maria Kost-Alimova, Mihir B. Doshi, William F. Harrington, Gavin Ha, April Cook, Uri Ben-David, Cheng-Zhong Zhang, Francisca Vazquez, Barbara A. Weir, Robin M. Meyers, Andrew J. Aguirre
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2cecf82a440fa137362f858bfcadb07
https://doi.org/10.1158/2159-8290.22531290
https://doi.org/10.1158/2159-8290.22531290
Autor:
Douglas F. Porter, Raghav M. Garg, Robin M. Meyers, Weili Miao, Luca Ducoli, Brian J. Zarnegar, Paul A. Khavari
Publikováno v:
Current Protocols. 3
Autor:
Vanessa Lopez-Pajares, Aparna Bhaduri, Yang Zhao, Gayatri Gowrishankar, Laura Donohue, Margaret G. Guo, Zurab Siprashvili, Weili Miao, Duy T. Nguyen, Albert M. Li, Ronald L. Shanderson, Robin M. Meyers, Angela Guerrero, Andrew L. Ji, Omar S. Garcia, Shiying Tao, Lindsey M. Meservey, Xue Yang, Sanjiv S. Gambhir, Jiangbin Ye, Paul A. Khavari
Glucose is a universal energy currency for living organisms, however, its non-energetic functions in processes such as differentiation are undefined. In epidermis, differentiating cells exhibit dynamic changes in gene expression1–4driven by specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e698bf765fcd141866c8457d8d03ee6
https://doi.org/10.1101/2022.11.28.518222
https://doi.org/10.1101/2022.11.28.518222
Autor:
Weili Miao, Douglas F. Porter, Vanessa Lopez-Pajares, Zurab Siprashvili, Robin M. Meyers, Yunhao Bai, Duy T. Nguyen, Lisa A. Ko, Brian J. Zarnegar, Ian D. Ferguson, Matthew M. Mills, Christie E. Jilly-Rehak, Cheng-Guo Wu, Yen-Yu Yang, Jordan M. Meyers, Audrey W. Hong, David L. Reynolds, Muthukumar Ramanathan, Shiying Tao, Sizun Jiang, Ryan A. Flynn, Yinsheng Wang, Garry P. Nolan, Paul A. Khavari
Publikováno v:
Cell. 186(1)
Glucose is a universal bioenergy source; however, its role in controlling protein interactions is unappreciated, as are its actions during differentiation-associated intracellular glucose elevation. Azido-glucose click chemistry identified glucose bi
Autor:
Douglas F Porter, Raghav M Garg, Robin M. Meyers, Weili Miao, Luca Ducoli, Brian J Zarnegar, Paul A Khavari
The easyCLIP protocol describes a method for both normal CLIP library construction and the absolute quantification of RNA cross-linking rates, data which could be usefully combined to analyze RNA-protein interactions. Using these cross-linking metric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0358c9b3bd76ad08e9cf65f6a6e7d2ad
https://doi.org/10.1101/2021.12.15.472862
https://doi.org/10.1101/2021.12.15.472862