Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Robin M Hobbs"'
Autor:
Hoi Ching Suen, Shitao Rao, Alfred Chun Shui Luk, Ruoyu Zhang, Lele Yang, Huayu Qi, Hon Cheong So, Robin M Hobbs, Tin-lap Lee, Jinyue Liao
Publikováno v:
eLife, Vol 12 (2023)
Spermatogenesis depends on an orchestrated series of developing events in germ cells and full maturation of the somatic microenvironment. To date, the majority of efforts to study cellular heterogeneity in testis has been focused on single-cell gene
Externí odkaz:
https://doaj.org/article/04602df871d347c3b7e92576a8ec5dc5
Autor:
Devi Ngo, Qiang Cheng, Anne E O'Connor, Kathleen D DeBoer, Camden Y Lo, Elaine Beaulieu, Mia De Seram, Robin M Hobbs, Moira K O'Bryan, Eric F Morand
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59149 (2013)
Spermatogonia stem cell (SSC) self-renewal and differentiation are tightly regulated processes that ensure a continued production of mature sperm throughout male adulthood. In the present study, we investigated the role of glucocorticoid-induced leuc
Externí odkaz:
https://doaj.org/article/33c67fd1907f4df18ade4154f8d139d6
Autor:
Sami Ventelä, Christophe Côme, Juho-Antti Mäkelä, Robin M Hobbs, Leni Mannermaa, Markku Kallajoki, Edward K Chan, Pier Paolo Pandolfi, Jorma Toppari, Jukka Westermarck
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33209 (2012)
Protein phosphatase 2A (PP2A) is a critical regulator of protein serine/threonine phosphorylation. However, the physiological and developmental roles of different PP2A complexes are very poorly understood. Here, we show that a newly characterized PP2
Externí odkaz:
https://doaj.org/article/a847f782e16f47129e4d8dd52c24a522
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Short-term germ cell survival and central tissue degeneration limit organoid cultures. Here, testicular organoids (TOs) were generated from two different mouse strains in 3D printed one-layer scaffolds (1LS) at the air-medium interface displaying tub
Externí odkaz:
https://doaj.org/article/f81238d084144c9d9c0419c981db797b
Autor:
Julien M. D. Legrand, Ai-Leen Chan, Hue M. La, Fernando J. Rossello, Minna-Liisa Änkö, Frances V. Fuller-Pace, Robin M. Hobbs
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-21 (2019)
Sustained sperm production is dependent on activity of undifferentiated spermatogonia. Here, the authors demonstrate an essential role for RNA helicase DDX5 in maintenance of spermatogonia in adults through control of gene transcription plus RNA proc
Externí odkaz:
https://doaj.org/article/852498ee4d314917b02f782d466e190b
Autor:
Hue M. La, Juho-Antti Mäkelä, Ai-Leen Chan, Fernando J. Rossello, Christian M. Nefzger, Julien M. D. Legrand, Mia De Seram, Jose M. Polo, Robin M. Hobbs
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Sustained spermatogenesis depends on stem cell activity which is contained within a population of undifferentiated spermatogonia. Here, the authors identify a new population of undifferentiated spermatogonia in adult testis that expresses the transcr
Externí odkaz:
https://doaj.org/article/87e119b967464304a757f01694a020cf
Autor:
Pier Paolo Pandolfi, Lewis C. Cantley, John G. Clohessy, Caterina Nardella, John M. Asara, Massimo Loda, Sabina Signoretti, Kaitlyn A. Webster, Christopher Ng, Andrea Lunardi, Ming Chen, Robin M. Hobbs, Antonella Papa, Mirjam T. Epping, Xue-Song Liu, Akash Patnaik, Min Sup Song, Su Jung Song, Nina Seitzer, Enrique González-Billalabeitia
PDF - 14407K, Supporting histology for Olaparib treatment in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353dca42c04c1e11621ce8aa8404957c
https://doi.org/10.1158/2159-8290.22530389.v1
https://doi.org/10.1158/2159-8290.22530389.v1
Autor:
Pier Paolo Pandolfi, Andrea Lunardi, Carlos Cordon-Cardo, Mireia Castillo-Martin, Roderick T. Bronson, Rosa Bernardi, Paolo Sportoletti, Min Sup Song, Robin M. Hobbs, Guocan Wang, Takahiro Maeda, Riccardo Taulli, Luisa Riccardi, Jlenia Guarnerio
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d620f754290e21262275036a9eeaf1e0
https://doi.org/10.1158/2159-8290.22530062
https://doi.org/10.1158/2159-8290.22530062
Autor:
Pier Paolo Pandolfi, Andrea Lunardi, Carlos Cordon-Cardo, Mireia Castillo-Martin, Roderick T. Bronson, Rosa Bernardi, Paolo Sportoletti, Min Sup Song, Robin M. Hobbs, Guocan Wang, Takahiro Maeda, Riccardo Taulli, Luisa Riccardi, Jlenia Guarnerio
Supplementary Figure S1. Candidate genes that couple with p53 loss to transform MSCs. Supplementary Figure S2. Lrf plays as oncosuppressor triggering tumorigenesis in MSCs. Supplementary Figure S3. Lrf expression does not affect the CFU-F capacities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::269f6ca1e7f74a0e3438f5c51c2c287f
https://doi.org/10.1158/2159-8290.22530059.v1
https://doi.org/10.1158/2159-8290.22530059.v1
Autor:
Pier Paolo Pandolfi, Sabina Signoretti, Carlos Cordon-Cardo, Mireia Castillo-Martin, Rodolfo Montironi, Laura Poliseno, Caterina Nardella, Alice H. Berger, Christopher Ng, Valentina Quarantotti, Robin M. Hobbs, Brett S. Carver, Tomoki Ishikawa, Nina Seitzer, Ugo Ala, Jlenia Guarnerio, Riccardo Taulli, Ming Chen, Shohreh Varmeh, Andrea Lunardi
Supplementary Figure S3. ERG binding to CHK1 promoter.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b1315a816fc729cdef3101dd0afe68
https://doi.org/10.1158/2159-8290.22530336.v1
https://doi.org/10.1158/2159-8290.22530336.v1