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pro vyhledávání: '"Robin L. Kilker"'
Supplementary Figure Legend from Cyclin D1 Is Necessary for Tamoxifen-Induced Cell Cycle Progression in Human Breast Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51db54f779b4cab0ffc4e7d245d1d891
https://doi.org/10.1158/0008-5472.22365927.v1
https://doi.org/10.1158/0008-5472.22365927.v1
Despite the success of tamoxifen in treating hormone-responsive breast cancer, its use is limited by the development of resistance to the drug. Understanding the pathways involved in the growth of tamoxifen-resistant cells may lead to new ways to tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd5eac7797d140153afaf21df04923d7
https://doi.org/10.1158/0008-5472.c.6494916
https://doi.org/10.1158/0008-5472.c.6494916
Supplementary Figure 1 from Cyclin D1 Is Necessary for Tamoxifen-Induced Cell Cycle Progression in Human Breast Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dbe3c144c156b995eb611bd467abec8
https://doi.org/10.1158/0008-5472.22365930.v1
https://doi.org/10.1158/0008-5472.22365930.v1
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 98:193-198
A common problem in breast cancer therapy is resistance to the antiestrogen tamoxifen. However, tamoxifen-resistant breast tumors can still respond to other hormonal therapies. In animal models of tamoxifen-resistant breast cancer cells, physiologica
Autor:
Hakan Sakul, Weizhen Xu, Michael North, Elizabeth Nanthakumar, Joseph H. Lee, R. Arlen Price, Callum J. Bell, Robin L. Kilker, Eun-Jeong Joo, Danielle R. Reed, Weidong Li
Publikováno v:
The American Journal of Human Genetics. 64:196-209
Obesity is a highly prevalent, multigenic trait that predicts increased morbidity and mortality. Here we report results from a genome scan based on 354 markers in 513 members of 92 nuclear families ascertained through extreme obesity and normal body
Publikováno v:
Diabetes. 51:1989-1991
Several groups have completed autosomal genome scans for human obesity, but only two have examined the X chromosome. A French group reported linkage of BMI to Xp and Xq markers, and a Finnish group reported linkage of BMI to Xq. We scanned the X chro
Publikováno v:
Cancer research. 66(23)
Despite the success of tamoxifen in treating hormone-responsive breast cancer, its use is limited by the development of resistance to the drug. Understanding the pathways involved in the growth of tamoxifen-resistant cells may lead to new ways to tre
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 92(1-2)
The development of resistance to tamoxifen, the most common antiestrogen used in the treatment of breast cancer, is a frequent and severe clinical problem. Tamoxifen-resistant tumors are still capable of responding to other hormonal therapies such as
Autor:
Wei Xu, Robin L. Kilker, Joseph H. Lee, R. Arlen Price, Weidong Li, Danielle R. Reed, B. R. Sodam
Publikováno v:
Annals of human genetics. 63(Pt 3)
Few mutations have been found in the human leptin gene and the relationship between leptin gene sequence variation and human overweight is uncertain. To determine whether sequence variation within the leptin gene and its regulatory elements contribut
Autor:
Michael North, Linda M. Bartoshuk, Elizabeth Nanthakumar, R A Price, Callum J. Bell, Danielle R. Reed
Publikováno v:
American journal of human genetics. 64(5)
The present work was supported by National Institutes of Health (NIH) grant R03DC03509 (to D.R.R).; NIH grants R01DK44073, R01DK48095, and funds from Axys Pharmaceuticals and Glaxo-Wellcome (to R.A.P.); and NIH grants 5M01RR00125-350922, 5R01DC00283,