Zobrazeno 1 - 10
of 599
pro vyhledávání: '"Robin L. Jones"'
Autor:
Yuen Bun Tam, Kaan Low, Hari PS, Madhumeeta Chadha, Jessica Burns, Christopher P. Wilding, Amani Arthur, Tom W. Chen, Khin Thway, Anguraj Sadanandam, Robin L. Jones, Paul H. Huang
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-11 (2024)
Abstract Background Adolescents and young adult (AYA) patients with soft tissue tumours including sarcomas are an underserved group with disparities in treatment outcomes. Methods To define the molecular features between AYA and older adult (OA) pati
Externí odkaz:
https://doaj.org/article/5c7704c5355142d48f5648cdb7b2c953
Autor:
Madhumeeta Chadha, Sara Iadecola, Andrew Jenks, Valeriya Pankova, Yuen Bun Tam, Jessica Burns, Amani Arthur, Christopher P. Wilding, Liang Chen, Priya Chudasama, Dario Callegaro, Dirk C. Strauss, Khin Thway, Alessandro Gronchi, Robin L. Jones, Rosalba Miceli, Sandro Pasquali, Paul H. Huang
Publikováno v:
Cancer Medicine, Vol 13, Iss 14, Pp n/a-n/a (2024)
Abstract Background High‐risk soft tissue sarcomas of the extremities and trunk wall (eSTS), as defined by the Sarculator nomogram, are more likely to benefit from (neo)adjuvant anthracycline‐based therapy compared to low/intermediate‐risk pati
Externí odkaz:
https://doaj.org/article/715b232d87c54af29f58e543b80e0753
Autor:
Denise Robinson, Hugh Leonard, Giacomo Giulio Baldi, William D. Tap, Robin L. Jones, Silvia Stacchiotti, Pan Pantziarka
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundEpithelioid hemangioendothelioma (EHE) is an ultra-rare, vascular sarcoma with clinical presentation ranging from an indolent to an aggressive form. Over 50% of patients present with metastatic disease, requiring systemic therapy, although
Externí odkaz:
https://doaj.org/article/9df29e33f2964648aa04e88d03235fc3
Autor:
Robin L. Jones, Marin Golčić
Publikováno v:
Cancer Biology & Medicine, Vol 20, Iss 10, Pp 701-705 (2023)
Externí odkaz:
https://doaj.org/article/3fbd31ea963f46e18d4dbcc9f17d3b1e
Autor:
Anne‐Rose W. Schut, Leanne E. deBruin, Belle H. deRooij, Emma Lidington, Milea J. M. Timbergen, Winette T. A. van derGraaf, Winan J. vanHoudt, Johannes J. Bonenkamp, Robin L. Jones, Dirk. J. Grünhagen, Stefan Sleijfer, Spyridon Gennatas, Cornelis Verhoef, Olga Husson
Publikováno v:
Cancer Medicine, Vol 12, Iss 12, Pp 13661-13674 (2023)
Abstract Background Desmoid‐type fibromatosis (DTF) has a highly variable clinical course with varying intensity of symptoms. The objectives of this study were to identify subgroups of DTF patients based on physical symptom burden and to compare sy
Externí odkaz:
https://doaj.org/article/68c9dc77427e4ed09f0bee452795e1f3
Autor:
Jessica Burns, Christopher P. Wilding, Lukas Krasny, Xixuan Zhu, Madhumeeta Chadha, Yuen Bun Tam, Hari PS, Aswanth H. Mahalingam, Alexander T. J. Lee, Amani Arthur, Nafia Guljar, Emma Perkins, Valeriya Pankova, Andrew Jenks, Vanessa Djabatey, Cornelia Szecsei, Frank McCarthy, Chanthirika Ragulan, Martina Milighetti, Theodoros I. Roumeliotis, Stephen Crosier, Martina Finetti, Jyoti S. Choudhary, Ian Judson, Cyril Fisher, Eugene F. Schuster, Anguraj Sadanandam, Tom W. Chen, Daniel Williamson, Khin Thway, Robin L. Jones, Maggie C. U. Cheang, Paul H. Huang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Soft tissue sarcomas (STS) are rare and diverse mesenchymal cancers with limited treatment options. Here we undertake comprehensive proteomic profiling of tumour specimens from 321 STS patients representing 11 histological subtypes. Within l
Externí odkaz:
https://doaj.org/article/9d213184d1a64b60a226a35cf5a6990a
Autor:
Su Yin Lim, Laura Ferro-López, Elizabeth Barquin, Daniel Lindsay, Khin Thway, Myles J. Smith, Charlotte Benson, Robin L. Jones, Andrea Napolitano
Publikováno v:
Cancers, Vol 16, Iss 5, p 985 (2024)
Ripretinib, a novel tyrosine kinase inhibitor used in advanced gastrointestinal stromal tumors (GIST) resistant to standard therapies, was assessed in the United Kingdom (UK) within an Expanded Access Program (EAP). A retrospective review of patients
Externí odkaz:
https://doaj.org/article/ef2b7b79c89d4103b091e6aee3953071
Autor:
Patrick Schöffski, Suzanne George, Michael C. Heinrich, John R. Zalcberg, Sebastian Bauer, Hans Gelderblom, César Serrano, Robin L. Jones, Steven Attia, Gina D’Amato, Ping Chi, Peter Reichardt, Claus Becker, Kelvin Shi, Julie Meade, Rodrigo Ruiz-Soto, Jean-Yves Blay, Margaret von Mehren
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Ripretinib is a novel switch-control kinase inhibitor that inhibits KIT and PDGFRA signaling. In the INVICTUS phase 3 trial, ripretinib increased median progression-free survival and prolonged overall survival vs. placebo in ≥ f
Externí odkaz:
https://doaj.org/article/9bb5658e944d433ba93df74a037e4505
Publikováno v:
Cancers, Vol 15, Iss 23, p 5619 (2023)
We appreciate the comment made by Chen et al. on our manuscript evaluating the systemic treatment options for gastrointestinal stromal tumours (GIST) [...]
Externí odkaz:
https://doaj.org/article/90d4d856d7b241838c72c612a839b499
Autor:
Steven Attia, Victor Villalobos, Nadia Hindi, Andrew J. Wagner, Bartosz Chmielowski, Gerard J. Oakley, Patrick M. Peterson, Matteo Ceccarelli, Robin L. Jones, Mark A. Dickson
Publikováno v:
Cancers, Vol 15, Iss 19, p 4871 (2023)
Gemcitabine plus docetaxel is an effective treatment regimen for advanced soft tissue sarcomas (STSs). However, the prognosis for patients remains poor, and thus there is an urgent medical need for novel and effective therapies to improve long-term o
Externí odkaz:
https://doaj.org/article/cd128dd911a645e3bb50b4ab5f6c6610