Výsledky vyhledávání - "Robin L. Cotter"

A Call to Assess the Impacts of Course-Based Undergraduate Research Experiences for Career and Technical Education, Allied Health, and Underrepresented Students at Community Colleges

Autor: Cori T, Leonetti, Heather, Lindberg, David Otto, Schwake, Robin L, Cotter

Publikováno v: CBE—Life Sciences Education. 22

Course-based undergraduate research experiences (CUREs) have the potential to impact student success and reduce barriers for students to participate in undergraduate research. Literature review has revealed that, while CUREs are being implemented at

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c8c8218f9713785713256ab2d6e703
https://doi.org/10.1187/cbe.21-11-0318

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Development of a rapid autopsy program for studies of brain immunity

Autor: Leslie A. Bruch, Jill Faraci, Spring Holter, Jane F. Potter, David Heilman, William H.C. Brown, Kathleen Borgmann, Anuja Ghorpade, VaKara Meyer, Yuri Persidsky, Susan Swindells, Howard E. Gendelman, Robin L. Cotter, Betty Chin, Raisa Persidsky, Li Wu

Publikováno v: Journal of Neuroimmunology. 163:135-144

Human glia are essential cellular models used for studies of neurodegenerative diseases. Fetal neuroglia are commonly used, as they can be recovered in large quantities and sustained for long periods in culture. However, fetal neuroglia may have limi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a196f703662c609089a1c0001bd452
https://doi.org/10.1016/j.jneuroim.2005.01.021

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Mitochondrial glutaminase enhances extracellular glutamate production in HIV-1-infected macrophages: Linkage to HIV-1 associated dementia

Autor: David Erichsen, Shelley Herek, Robin L. Cotter, Jianxing Zhao, Jialin C. Zheng, Alicia L. Lopez, Norman P. Curthoys

Publikováno v: Journal of Neurochemistry. 88:169-180

Dysfunction in mononuclear phagocyte (MP, macrophages and microglia) immunity is thought to play a significant role in the pathogenesis of HIV-1 associated dementia (HAD). In particular, elevated extracellular concentrations of the excitatory neurotr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fd5dfb25f65d3ffb0895fbb3a8556359
https://doi.org/10.1046/j.1471-4159.2003.02146.x

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HIV-1 infected immune competent mononuclear phagocytes influence the pathways to neuronal demise

Autor: Walter E. Zink, Anuja Ghorpade, Michael R. Thylin, Robin L. Cotter, Jialin C. Zheng, Kathleen Lewis, Yuri Persidsky, Lisa A. Ryan, Clancy E. Williams, Howard E. Gendelman

Publikováno v: Neurotoxicity Research. 3:461-484

Secretory products from HIV-1-infected immune-competent mononuclear phagocytes (MP) damage neuronal dendritic arbor (Zheng et al., 2001). The mechanism behind neuronal injury and whether it is species and/or viral strain dependent is not fully unders

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f54c41d59107f4dbe24087ada76d9985
https://doi.org/10.1007/bf03033204

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Insights into the neurodegenerative process of Alzheimer's disease: a role for mononuclear phagocyte-associated inflammation and neurotoxicity

Autor: Robin L. Cotter, William J. Burke, Jane F. Potter, Jialin C. Zheng, Vince Salazar Thomas, Howard E. Gendelman

Publikováno v: Journal of Leukocyte Biology. 65:416-427

Since the first description of Alzheimer's disease (AD) in 1907, significant progress was made into understanding disease pathophysiology. The enormous effort in AD research has translated into the discovery of genetic linkages for disease, into eluc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::648d4e40bb8bee132bd594605dfd70ae
https://doi.org/10.1002/jlb.65.4.416

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Neuroinflammatory responses from microglia recovered from HIV-1-infected and seronegative subjects

Autor: Robin L. Cotter, Raisa Persidsky, Y. Persidsky, Susan Swindells, Howard E. Gendelman, Anuja Ghorpade, Spring Holter, Kathleen Borgmann

Publikováno v: Journal of neuroimmunology. 163(1-2)

Microglial and macrophage infection and immune activation underlie the pathogenesis of HIV-1-associated dementia (HAD). To assess microglial function in HAD, we isolated cells from brain tissues recovered from an HIV-1-infected patient within 4 h of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fc56d017614609fa29ffd1d3dd5f5f9
https://pubmed.ncbi.nlm.nih.gov/15869805

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HIV-1 infected and immune competent mononuclear phagocytes induce quantitative alterations in neuronal dendritic arbor: relevance for HIV-1-associated dementia

Autor: Yuri Persidsky, Gary Leisman, Howard E. Gendelman, Michael R. Thylin, Huangui Xiong, Anuja Ghorpade, My Hanh Che, Robin L. Cotter, Alicia L. Lopez, Jialin C. Zheng

Publikováno v: Neurotoxicity research. 3(5)

Neuronal loss, alterations in dendritic arbor, and decreased synaptic density, in infected brain tissue, are neuropathological signatures of HIV-1-associated dementia (HAD). Brain mononuclear phagocyte (MP) (macrophage and microglia) secretory produc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::490d38f0a57450dfd5950a1b7430a391
https://pubmed.ncbi.nlm.nih.gov/14715458

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Mitochondrial glutaminase enhances extracellular glutamate production in HIV-1-infected macrophages: linkage to HIV-1 associated dementia

Autor: Jianxing, Zhao, Alicia L, Lopez, David, Erichsen, Shelley, Herek, Robin L, Cotter, Norman P, Curthoys, Jialin, Zheng

Publikováno v: Journal of neurochemistry. 88(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::04a204b153d0b37c22676e4625b49371
https://pubmed.ncbi.nlm.nih.gov/14675161

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Neuronal injury regulates fractalkine: relevance for HIV-1 associated dementia

Autor: Lisa A. Ryan, Anuja Ghorpade, Clancy E. Williams, Robin L. Cotter, Howard E. Gendelman, Jialin C. Zheng, Douglas Niemann, Alicia L. Lopez, Michael Bauer, Susan Morgello, David Erichsen, Hui Peng

Publikováno v: Journal of neuroimmunology. 138(1-2)

Fractalkine (FKN), a chemokine highly expressed in the central nervous system, participates in inflammatory responses operative in many brain disorders including HIV-1 associated dementia (HAD). In this report, HIV-1 progeny virions and pro-inflammat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b3d81879fda0f99e2987fc3331dad5
https://pubmed.ncbi.nlm.nih.gov/12742664

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Fractalkine (CX3CL1) and brain inflammation: Implications for HIV-1-associated dementia

Autor: C Williams, David Erichsen, Robin L. Cotter, Jialin C. Zheng, A Lopez, L Ryan, Hui Peng

Publikováno v: Journal of neurovirology. 8(6)

Leukocyte migration and activation play an important role in immune surveillance and the pathogenesis of a variety of neurodegenerative disorders, including human immunodeficiency virus (HIV)-1-associated dementia (HAD). A novel chemokine named fract

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d110f4ff8c34b35a410c32f25d38004c
https://pubmed.ncbi.nlm.nih.gov/12476352

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