Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Robin L. Blumenthal"'
Autor:
Kenneth C. Cundy, Dan Chen, Wendy Luo, Juthamas Sukbuntherng, Ritu Lal, Robin L. Blumenthal, Judy Ho
Publikováno v:
Clinical Therapeutics. 34:201-213
Gabapentin enacarbil, a transported acyloxyalkylcarbamate prodrug of gabapentin, provides predictable and dose-proportional gabapentin exposure (AUC). Gabapentin is cleared via renal excretion, and its elimination is proportional to creatinine cleara
Autor:
Robin L. Blumenthal, Judy Ho, Kenneth C. Cundy, Wendy Luo, Juthamas Sukbuntherng, Virna Vicente, Ritu Lal
Publikováno v:
British Journal of Clinical Pharmacology. 69:498-507
AIM Gabapentin enacarbil, a transported prodrug of gabapentin, provides sustained, dose-proportional exposure to gabapentin. Unlike gabapentin, the prodrug is absorbed throughout the intestinal tract by high-capacity nutrient transporters, including
Autor:
Paul Hwang, Rosemarie H. DeKruyff, Robin L. Blumenthal, Dale T. Umetsu, Dianne E. Campbell, Lorry R. Frankel
Publikováno v:
Journal of Allergy and Clinical Immunology. 107:258-264
Background: Alveolar macrophages (AMCs) are the most abundant phagocytic cells in the lung, but they present antigen poorly to T cells. Objectives: The objectives of our studies were to more clearly define the mechanisms by which AMCs present antigen
Autor:
Robin L. Blumenthal, Gerald J. Berry, Rosemarie H. DeKruyff, Dale T. Umetsu, Daphne C. Tsitoura
Publikováno v:
Journal of Allergy and Clinical Immunology. 106:239-246
Background: Aeroallergens continuously enter the respiratory tract of atopic individuals and provoke the development of asthma characterized by airway hyperreactivity (AHR) and inflammation. By contrast, nonatopic individuals are exposed to the same
Autor:
Linda Stein Gold, Robert S. Call, Douglass W. Forsha, Matilda H. Hughes, Wynnis L. Tom, Adelaide A. Hebert, Lee T. Zane, Amy S. Paller, Eric L. Simpson, Andrea L. Zaenglein, Mary Spellman, Lawrence F. Eichenfield, William C. Rees, Mark Lebwohl, Robin L. Blumenthal, Mark Boguniewicz
Publikováno v:
Journal of the American Academy of Dermatology. 75:494-503.e6
BackgroundAdditional topical treatments for atopic dermatitis (AD) are needed that provide relief while minimizing risks.ObjectiveWe sought to assess the efficacy and safety of crisaborole ointment, a phosphodiesterase 4 inhibitor, in two phase III A
Autor:
Lee Thomas Zane, Amy S. Paller, Wynnis L. Tom, Mark G. Lebwohl, Robin L. Blumenthal, Mark Boguniewicz, Robert S. Call, Lawrence F. Eichenfield, Douglass W. Forsha, William C. Rees, Eric L. Simpson, Linda F. Stein Gold, Andrea L. Zaenglein, Adelaide A. Hebert
Publikováno v:
The Journal of Immunology. 196:191.26-191.26
Up to 90% of children and adults with atopic dermatitis (AD), a chronic inflammatory skin disease, present with mild-to-moderate disease. Crisaborole Topical Ointment, 2%, is a novel, nonsteroidal, topical, anti-inflammatory, phosphodiesterase 4 inhi
Autor:
Robert S. Call, Mark M. Lebwohl, Linda Stein Gold, Robin L. Blumenthal, Amy S. Paller, Eric L. Simpson, Lawrence Eichenfield, Mark Boguniewicz, Douglass W. Forsha, Lee T. Zane, Wynnis L. Tom, Andrea L. Zaenglein, Adelaide A. Hebert, William C. Rees
Publikováno v:
Journal of the American Academy of Dermatology. 74:AB86
Autor:
Eric L. Simpson, Mark Lebwohl, Adelaide A. Hebert, Robert S. Call, Wynnis L. Tom, Lee T. Zane, Andrea L. Zaenglein, Matty H. Hughes, Linda Stein Gold, Lawrence F. Eichenfield, Robin L. Blumenthal, Amy S. Paller, William C. Rees, Douglass W. Forsha, Mark Boguniewicz
Publikováno v:
Journal of Allergy and Clinical Immunology. 137:AB397
Autor:
Kai W. Wucherpfennig, Steven P. Balk, Robin L. Blumenthal, E C Ebert, Richard S. Blumberg, Francis V. Mcdermott, Steven B. Landau
Publikováno v:
Science. 253:1411-1415
A human intestinal intraepithelial lymphocyte (IEL) T cell line was established from jejunum to characterize the structure and function of the alpha beta T cell antigen receptors (TCRs) expressed by this population. Single-sided polymerase chain reac
Autor:
Kurt F. Seetoo, Elizabeth R. Simons, John Bernardo, Robin L. Blumenthal, Matthew J. Fenton, Andrea M. Billingslea
Publikováno v:
Infection and immunity. 66(1)
CD14 is a signaling receptor for both gram-negative bacterial lipopolysaccharide (LPS) and mycobacterial lipoarabinomannan (LAM) that lacks terminal mannosyl units (AraLAM). In contrast, terminally mannosylated LAM (ManLAM) binds the macrophage manno