Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Robin L Kirkpatrick"'
Autor:
Michele LeRoux, Robin L Kirkpatrick, Elena I Montauti, Bao Q Tran, S Brook Peterson, Brittany N Harding, John C Whitney, Alistair B Russell, Beth Traxler, Young Ah Goo, David R Goodlett, Paul A Wiggins, Joseph D Mougous
Publikováno v:
eLife, Vol 4 (2015)
The perception and response to cellular death is an important aspect of multicellular eukaryotic life. For example, damage-associated molecular patterns activate an inflammatory cascade that leads to removal of cellular debris and promotion of healin
Externí odkaz:
https://doaj.org/article/5b86101dfd184aa9950b938e2b29db83
Autor:
Robert A. Langan, Madeleine Eakman, Robin L. Kirkpatrick, Marc J. Lajoie, Jesse G. Zalatan, David Baker, Kieran Lewis, Scott E. Boyken
Publikováno v:
ACS Synth Biol
To spatially control biochemical functions at specific sites within a genome, we have engineered a synthetic switch that activates when bound to its DNA target site. The system uses two CRISPR-Cas complexes to colocalize components of a de novo desig
Autor:
Daniel Cunningham-Bryant, Brianna Fernandez, Jesse G. Zalatan, Emily R. Cliff, Joseph L. Harman, Robin L. Kirkpatrick
Publikováno v:
ACS Synth Biol
To investigate the relationship between genome structure and function, we have developed a programmable CRISPR-Cas system for nuclear peripheral recruitment in yeast. We benchmarked this system at the HMR and GAL2 loci, both of which are well-charact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86f238d6b13d32983043608fb782097
https://europepmc.org/articles/PMC8627703/
https://europepmc.org/articles/PMC8627703/
Autor:
Emily R. Cliff, Robin L. Kirkpatrick, Jesse G. Zalatan, Brianna Fernandez, Daniel Cunningham-Bryant
To investigate the relationship between genome structure and function, we have developed a programmable CRISPR-Cas system for nuclear peripheral recruitment in yeast. We benchmarked this system at the HMR and GAL2 loci, both well-characterized model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80541b65871a0f8a1657f45e9ba151a8
https://doi.org/10.1101/2021.04.30.442211
https://doi.org/10.1101/2021.04.30.442211
Autor:
Keith C. Johnson, Robin L. Kirkpatrick, Juan C. Vizcarra, Wendy E. Thomas, Hani Mahmoud, Emilie Warner Clemmens
Publikováno v:
Journal of Biological Engineering
Journal of Biological Engineering, Vol 11, Iss 1, Pp 1-13 (2017)
Journal of Biological Engineering, Vol 11, Iss 1, Pp 1-13 (2017)
Background In the past two decades, methods have been developed to measure the mechanical properties of single biomolecules. One of these methods, Magnetic tweezers, is amenable to acquisition of data on many single molecules simultaneously, but to t
Autor:
Michele LeRoux, Kirsty A. McFarland, Tracy K. Kambara, Robin L. Kirkpatrick, Joseph D. Mougous, Emily L. Dolben, Kathryn M. Ramsey, Deborah A. Hogan, Simon L. Dove
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(27)
In mammalian cells, programmed cell death (PCD) plays important roles in development, in the removal of damaged cells, and in fighting bacterial infections. Although widespread among multicellular organisms, there are relatively few documented instan
Autor:
Beth Traxler, David R. Goodlett, Young Ah Goo, Alistair B. Russell, Brittany N. Harding, Robin L. Kirkpatrick, Elena I. Montauti, John C. Whitney, Michele LeRoux, Bao Q. Tran, Paul A. Wiggins, S. Brook Peterson, Joseph D. Mougous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69aea68fe12d9876426b9e429cf98970
https://doi.org/10.7554/elife.05701.032
https://doi.org/10.7554/elife.05701.032
Publikováno v:
Biophysical Journal. 108(2)
The Type Six Secretion System (T6SS) is a bacterial toxin-delivery system targeting bacterial cells which neighbor the donor, promoting recipient cell death. The T6SS is widely conserved among Gram-negative bacteria and may be a central determinant i
Autor:
Beth Traxler, Alistair B. Russell, John C. Whitney, Brittany N. Harding, S. Brook Peterson, Joseph D. Mougous, Young Ah Goo, David R. Goodlett, Robin L. Kirkpatrick, Elena I. Montauti, Michele LeRoux, Bao Q. Tran, Paul A. Wiggins
Publikováno v:
eLife
eLife, Vol 4 (2015)
eLife, Vol 4 (2015)
The perception and response to cellular death is an important aspect of multicellular eukaryotic life. For example, damage-associated molecular patterns activate an inflammatory cascade that leads to removal of cellular debris and promotion of healin