Výsledky vyhledávání - "Robin Krueger"

Akademický článek

Boosting Natural Killer Cell-Mediated Targeting of Sarcoma Through DNAM-1 and NKG2D

Autor: Ece Canan Sayitoglu, Anna-Maria Georgoudaki, Michael Chrobok, Didem Ozkazanc, Benjamin J. Josey, Muhammad Arif, Kim Kusser, Michelle Hartman, Tamara M. Chinn, Renee Potens, Cevriye Pamukcu, Robin Krueger, Cheng Zhang, Adil Mardinoglu, Evren Alici, Harry Thomas Temple, Tolga Sutlu, Adil Doganay Duru

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

Sarcomas are malignancies of mesenchymal origin that occur in bone and soft tissues. Many are chemo- and radiotherapy resistant, thus conventional treatments fail to increase overall survival. Natural Killer (NK) cells exert anti-tumor activity upon

Externí odkaz: https://doaj.org/article/7661b8daeda441778d5cd52335100e15

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Abstract A23: Identification of prevalent targets for the development of tailored sarcoma immunotherapies using a rapid clinic-to-bench immunoprofiling pipeline

Autor: H. Thomas Temple, Dustin Tran, Robin Krueger, Adil Doganay Duru, Anna-Maria Georgoudaki, Renee Potens, Wendy W. Weston, Michelle Hartman, Tamara M. Chinn

Publikováno v: Cancer Immunology Research. 8:A23-A23

Sarcomas are rare malignancies of mesenchymal origin for which current treatment options are very limited. Due to the vast heterogeneity of the various subtypes, the development of new targeted therapies requires a customized approach. Checkpoint blo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b464097da33ab8867b1dadc6ce69a58e
https://doi.org/10.1158/2326-6074.tumimm18-a23

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Abstract A55: Natural killer cells genetically modified to overexpress DNAM-1 exert enhanced antitumor responses against CD112/CD155+ sarcomas and other malignancies

Autor: Robin Krueger, Harry T. Temple, Savannah Bergeron, Evren Alici, Michelle Hartman, Rajeev Herekar, Ece Canan Sayitoglu, Tolga Sutlu, Esha Vallabhaneni, Adil Doganay Duru, Michael Chrobok, Benjamin J. Josey, Anna-Maria Georgoudaki

Publikováno v: Cancer Immunology Research. 8:A55-A55

Sarcomas are a broad category of cancers arising from cells of mesenchymal origin that occur in bone and soft tissues. They affect humans of all ages, and standard treatment options remain ineffective at increasing overall survival. Targeted immunoth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1439a85711decf66b6df14f3a40440fc
https://doi.org/10.1158/2326-6074.tumimm18-a55

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