Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Robin Kopp"'
Autor:
Juan Sierra-Marquez, Lena Schaller, Lukas Sassenbach, Antonio Ramírez-Fernández, Philipp Alt, Björn Rissiek, Béla Zimmer, Johann Schredelseker, Julia Hector, Tobias Stähler, Friedrich Koch-Nolte, Claudia A. Staab-Weijnitz, Alexander Dietrich, Robin Kopp, Annette Nicke
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionP2X receptors are a family of homo- and heterotrimeric cation channels gated by extracellular ATP. The P2X4 and P2X7 subunits show overlapping expression patterns and have been involved in similar physiological processes, such as pain and
Externí odkaz:
https://doaj.org/article/b55a6bb7bcc24c3691c0c6357b0bf403
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Extracellular adenine nucleotides play important roles in cell–cell communication and tissue homeostasis. High concentrations of extracellular ATP released by dying cells are sensed as a danger signal by the P2X7 receptor, a non-specific cation cha
Externí odkaz:
https://doaj.org/article/d86b62d93fd84d9f94a0a62abfe0092e
Autor:
Karina Kaczmarek-Hajek, Jiong Zhang, Robin Kopp, Antje Grosche, Björn Rissiek, Anika Saul, Santina Bruzzone, Tobias Engel, Tina Jooss, Anna Krautloher, Stefanie Schuster, Tim Magnus, Christine Stadelmann, Swetlana Sirko, Friedrich Koch-Nolte, Volker Eulenburg, Annette Nicke
Publikováno v:
eLife, Vol 7 (2018)
The P2X7 channel is involved in the pathogenesis of various CNS diseases. An increasing number of studies suggest its presence in neurons where its putative functions remain controversial for more than a decade. To resolve this issue and to provide a
Externí odkaz:
https://doaj.org/article/b062997e054c49a3929a6f440c8b1a7e
Autor:
Daniel J. Jagger, Silvia Prades, Jonathan E. Gale, Gregory Heard, Robin Kopp, Annette Nicke, Katie E. Smith, Tobias Engel
Publikováno v:
The Journal of Neuroscience. 41:2615-2629
P2X7receptors (P2X7Rs) are associated with numerous pathophysiological mechanisms, and this promotes them as therapeutic targets for certain neurodegenerative conditions. However, the identity of P2X7R-expressing cells in the nervous system remains c
Autor:
Philip A. Gurnev, Ohyun Kwon, Robin Kopp, Johann Schredelseker, Annette Nicke, Nathan J. Dupper, Anna Schedel, Fabiola Wilting, Thomas Gudermann
Publikováno v:
British Journal of Pharmacology
Background and Purpose The synthetic compound efsevin was recently identified to suppress arrhythmogenesis in models of cardiac arrhythmia, making it a promising candidate for antiarrhythmic therapy. Its activity was shown to be dependent on the volt
Autor:
Antonio Ramírez-Fernández, Lidia Urbina-Treviño, Giorgia Conte, Mariana Alves, Björn Rissiek, Anna Durner, Nicolas Scalbert, Jiong Zhang, Tim Magnus, Friedrich Koch-Nolte, Nikolaus Plesnila, Jan M. Deussing, Tobias Engel, Robin Kopp, Annette Nicke
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
The ATP-gated P2X7 receptor is highly expressed in microglia and has been involved in diverse brain diseases. P2X7 effects were also described in neurons and astrocytes but its localisation and function in these cell types has been challenging to dem
Autor:
Silvia, Prades, Gregory, Heard, Jonathan E, Gale, Tobias, Engel, Robin, Kopp, Annette, Nicke, Katie E, Smith, Daniel J, Jagger
Publikováno v:
J Neurosci
P2X(7) receptors (P2X(7)Rs) are associated with numerous pathophysiological mechanisms, and this promotes them as therapeutic targets for certain neurodegenerative conditions. However, the identity of P2X(7)R-expressing cells in the nervous system re
Autor:
Ohyun Kwon, Johann Schredelseker, Nathan J. Dupper, Philip A. Gurnev, Fabiola Wilting, Thomas Gudermann, Anna Schedel, Robin Kopp, Annette Nicke
Publikováno v:
Biophysical Journal. 118:406a
Autor:
Tobias Engel, Anna Krautloher, Tina Jooss, Karina Kaczmarek-Hajek, Björn Rissiek, Jiong Zhang, Volker Eulenburg, Christine Stadelmann, Stefanie Schuster, Tim Magnus, Antje Grosche, Anika Saul, Robin Kopp, Santina Bruzzone, Annette Nicke, Friedrich Koch-Nolte, Swetlana Sirko
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f417bccfe06f0127196450a17b79f81
https://doi.org/10.7554/elife.36217.030
https://doi.org/10.7554/elife.36217.030
Autor:
Swetlana Sirko, Christine Stadelmann, Friedrich Koch-Nolte, Antje Grosche, Tina Jooss, Tobias Engel, Anna Krautloher, Tim Magnus, Robin Kopp, Santina Bruzzone, Björn Rissiek, Annette Nicke, Jiong Zhang, Volker Eulenburg, Annika Saul, Karina Kaczmarek-Hajek, Stefanie Schuster
Publikováno v:
eLife
eLife 7:e36217 (2018)
eLife, Vol 7 (2018)
eLife 7:e36217 (2018)
eLife, Vol 7 (2018)
The P2X7 channel is involved in the pathogenesis of various CNS diseases. An increasing number of studies suggest its presence in neurons where its putative functions remain controversial for more than a decade. To resolve this issue and to provide a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca713e80453341a88f2e1bc4b7740ca3
http://hdl.handle.net/11567/920630
http://hdl.handle.net/11567/920630