Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Robin J. Breckenridge"'
Publikováno v:
Tetrahedron. 42:5665-5677
Electrophilic cyclopropane-containing compounds have been found in our previous studies to be latent, irreversible inhibitors of horse liver alcohol dehydrogenase, lactate dehydrogenase, and carboxypeptidase A. In addition, cyclopropyl methanols have
Autor:
Sydney H. Nicholson, Leslie Iversen, Beatrice Leigh, Robin J. Breckenridge, Colin J. Suckling, Alan J. Nicol
Publikováno v:
Biochemical Pharmacology. 30:3045-3049
Thirty three synthetic analogues of GABA were tested for their ability to act as inhibitors of neuronal or glial uptake sites for GABA and β-alanine, using [ 3 H]GABA uptake by synaptosome preparations from rat cerebral cortex, and [ 3 H]β-alanine
Autor:
Leslie L. Iversen, K. J. Watling, Robin J. Breckenridge, Lindsey C. Williams, Sukhvinder S. Bansal, Colin J. Suckling
Publikováno v:
Biochemical Pharmacology. 34:4173-4177
Autor:
Leslie L. Iversen, Beatrice Leigh, Robin J. Breckenridge, Alan J. Nicol, Sydney H. Nicholson, Colin J. Suckling
Publikováno v:
Journal of Neurochemistry. 37:837-844
Fifty synthetic analogues of GABA were tested for their ability ot interact with GABA receptors, using [3H]GABA binding to human cerebellar membranes as an in vitro model. The most active compounds were found to be aliphatic and heterocyclic aminosul
Autor:
Derek C. Nonhebel, David R. Armstrong, Peter G. Perkins, Colin Cameron, Robin J. Breckenridge, Peter L. Pauson
Publikováno v:
Tetrahedron Letters. 24:1071-1074
The oxidative coupling of both 3,5-dimethylphenol and phenol leads to the ortho-ortho and ortho-para coupled products as the predominant C-C dimers: stereoelectronic factors determine the preferred mode of approach of the phenoxyl radicals.
Publikováno v:
Journal of theoretical biology. 97(2)
Ab initio molecular orbital calculations have been carried out on muscimol (1) and on two aza analogues, 5-aminomethylpyrazol-3-one (2) and 5-aminomethyl-1,2,4-triazol-3-one (3). Fully ionized species were studied in each case including the tautomeri