Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Robin J Marjoram"'
Autor:
Robin J Marjoram, Zhengzhi Li, Li He, Douglas M Tollefsen, Thomas J Kunicki, S Kent Dickeson, Samuel A Santoro, Mary M Zutter
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e114035 (2014)
Platelets express the α2β1 integrin and the glycoprotein VI (GPVI)/FcRγ complex, both collagen receptors. Understanding platelet-collagen receptor function has been enhanced through use of genetically modified mouse models. Previous studies of GPV
Externí odkaz:
https://doaj.org/article/a0186060a2c64848bb49810c27afac21
Publikováno v:
The Journal of Immunology. 174:6927-6933
The IL-8 (or CXCL8) chemokine receptors, CXCR1 and CXCR2, activate protein kinase C (PKC) to mediate leukocyte functions. To investigate the roles of different PKC isoforms in CXCL8 receptor activation and regulation, human mononuclear phagocytes wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8c7cc24149b1f338c1b533a26665ef4
https://doi.org/10.4049/jimmunol.174.11.6927
https://doi.org/10.4049/jimmunol.174.11.6927
Autor:
Jeffery J. Delrow, Michelle L. Bowie, Eric C. Dietze, Victoria L. Seewaldt, Gregory R. Bean, Michelle M. Troch, Robin J. Marjoram
Publikováno v:
Oncogene. 23:8743-8755
Unlike estrogen receptor-positive (ER(+)) breast cancers, normal human mammary epithelial cells (HMECs) typically express low nuclear levels of ER (ER poor). We previously demonstrated that 1.0 microM tamoxifen (Tam) promotes apoptosis in acutely dam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9adb8867326acc7b2ead6da21aeb3d8e
https://doi.org/10.1038/sj.onc.1208120
https://doi.org/10.1038/sj.onc.1208120
Publikováno v:
Journal of Biological Chemistry. 278:15867-15873
Human immunodeficiency virus type 1 (HIV-1) entry into CD4(+) cells requires the chemokine receptors CCR5 or CXCR4 as co-fusion receptors. We have previously demonstrated that chemokine receptors are capable of cross-regulating the functions of each
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5e7862ad7f0665a316dc766fb61e887
https://doi.org/10.1074/jbc.m211745200
https://doi.org/10.1074/jbc.m211745200
Publikováno v:
The Journal of Immunology. 170:2904-2911
IL-8 (or CXCL8) activates the receptors CXCR1 (IL-8RA) and CXCR2 (IL-8RB) to induce chemotaxis in leukocytes, but only CXCR1 mediates cytotoxic and cross-regulatory signals. This may be due to the rapid internalization of CXCR2. To investigate the ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f029936f0c77c6b48363dab666dff8
https://doi.org/10.4049/jimmunol.170.6.2904
https://doi.org/10.4049/jimmunol.170.6.2904
Publikováno v:
Biochemistry. 40:3583-3588
To define the role of regulators of G-protein signaling (RGS) in chemoattractant-mediated responses, RGS4 and the receptors for platelet-activating factor (PAFR), formylated peptides (FR), or interleukin-8 (CXCR1) were stably coexpressed in a rat bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa5a1b50fcfda68ac8a76baea8d25fb
https://doi.org/10.1021/bi0019242
https://doi.org/10.1021/bi0019242
Autor:
Michelle L. Bowie, Kazunari K. Yokoyama, Michelle M. Troch, L. Elizabeth Caldwell, Victoria L. Seewaldt, Cassandra L. Neal, Robin J. Marjoram, Krzysztof Mrózek, Gregory R. Bean, Eric C. Dietze, Catherine Ibarra
Publikováno v:
Journal of cell science. 118(Pt 21)
Interactions between normal mammary epithelial cells and extracellular matrix (ECM) are important for mammary gland homeostasis. Loss of interactions between ECM and normal mammary epithelial cells are thought to be an early event in mammary carcinog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d63fdeb4ff0111dd0de1bf7d4ba451
https://pubmed.ncbi.nlm.nih.gov/16219677
https://pubmed.ncbi.nlm.nih.gov/16219677
Publikováno v:
Biochemical and biophysical research communications. 293(1)
Phospholipase C (PLC)-beta enzymes (isoenzymes beta 1-beta 4) are activated by G protein subunits, leading to the generation of intracellular messengers which mobilize calcium and activate protein kinase C. It has recently been recognized that these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc4070ec0bd6fb3abbaa6239ff686853
https://pubmed.ncbi.nlm.nih.gov/12054652
https://pubmed.ncbi.nlm.nih.gov/12054652