Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Robin J Hofmeister"'
Publikováno v:
PLoS Genetics, Vol 20, Iss 7, p e1011092 (2024)
Haplotype estimation, or phasing, has gained significant traction in large-scale projects due to its valuable contributions to population genetics, variant analysis, and the creation of reference panels for imputation and phasing of new samples. To s
Externí odkaz:
https://doaj.org/article/048bb794ac0f44a79e5458cb4a356983
Autor:
Robin J. Hofmeister, Simone Rubinacci, Diogo M. Ribeiro, Alfonso Buil, Zoltán Kutalik, Olivier Delaneau
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Studies on parent-of-origin effects have been limited in terms of sample size due to lack of parental genomes or known genealogies. Here, the authors develop a method to infer the parent-of-origin of an individual alleles in biobank-scale datasets, w
Externí odkaz:
https://doaj.org/article/77090dd6063a448986bd889a487ceecd
Autor:
Diogo M. Ribeiro, Simone Rubinacci, Anna Ramisch, Robin J. Hofmeister, Emmanouil T. Dermitzakis, Olivier Delaneau
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Local gene co-expression is found throughout the genome, but systematic analysis of these co-expressed genes is needed. Here, the authors identify local co-expressed genes in 49 tissues and characterize the genetic variants which may affect their exp
Externí odkaz:
https://doaj.org/article/631aadc85a424e45a6de0ce58d753ad5
Publikováno v:
Nature Genetics. 53:120-126
Low-coverage whole-genome sequencing followed by imputation has been proposed as a cost-effective genotyping approach for disease and population genetics studies. However, its competitiveness against SNP arrays is undermined because current imputatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::466b93992ff85ed62afbff0e57ad712b
https://doi.org/10.1038/s41588-020-00756-0
https://doi.org/10.1038/s41588-020-00756-0
Autor:
Simone Rubinacci, Zoltán Kutalik, Diogo M. Ribeiro, Alfonso Buil, Olivier Delaneau, Robin J. Hofmeister
Identical genetic variations can have different phenotypic effects depending on their parent of origin (PofO). Yet, studies focussing on PofO effects have been largely limited in terms of sample size due to the need of parental genomes or known genea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f2e1b819e3f6d72f256daf9a4e2519
https://doi.org/10.1101/2021.11.03.467079
https://doi.org/10.1101/2021.11.03.467079
Autor:
Olivier Delaneau, Robin J. Hofmeister, Emmanouil T. Dermitzakis, Anna Ramisch, Simone Rubinacci, Diogo M. Ribeiro
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature communications, vol. 12, no. 1, pp. 4842
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature communications, vol. 12, no. 1, pp. 4842
Nearby genes are often expressed as a group. Yet, the prevalence, molecular mechanisms and genetic control of local gene co-expression are far from being understood. Here, by leveraging gene expression measurements across 49 human tissues and hundred
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b6c704c619e13d633ebc32bbebce67e
Publikováno v:
Nature genetics. 53(1)
Low-coverage whole-genome sequencing followed by imputation has been proposed as a cost-effective genotyping approach for disease and population genetics studies. However, its competitiveness against SNP arrays is undermined because current imputatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1c59a0d07fc3571527eb5e375ddc3992
https://pubmed.ncbi.nlm.nih.gov/33473199
https://pubmed.ncbi.nlm.nih.gov/33473199
Low-coverage whole genome sequencing followed by imputation has been proposed as a cost-effective genotyping approach for disease and population genetics studies. However, its competitiveness against SNP arrays is undermined as current imputation met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1c0107489228d02cf6b4dd6b169e9e
https://doi.org/10.1101/2020.04.14.040329
https://doi.org/10.1101/2020.04.14.040329
Publikováno v:
Nature Genetics. 53:412-412
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b455d8703e67c0a8d0655aeee04c1d1f
https://doi.org/10.1038/s41588-021-00788-0
https://doi.org/10.1038/s41588-021-00788-0
Autor:
Wertenbroek, Rick1,2 (AUTHOR) rick.wertenbroek@unil.ch, Hofmeister, Robin J.1 (AUTHOR), Xenarios, Ioannis1 (AUTHOR), Thoma, Yann2 (AUTHOR), Delaneau, Olivier3 (AUTHOR) rick.wertenbroek@unil.ch
Publikováno v:
PLoS Genetics. 7/3/2024, Vol. 20 Issue 7, p1-22. 22p.