Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Robin J Flynn"'
Vivaxin genes encode highly immunogenic, non-variant antigens on the Trypanosoma vivax cell-surface.
Autor:
Alessandra Romero-Ramirez, Aitor Casas-Sánchez, Delphine Autheman, Craig W Duffy, Cordelia Brandt, Simon Clare, Katherine Harcourt, Marcos Rogério André, Kayo José Garcia de Almeida Castilho Neto, Marta M G Teixeira, Rosangela Zacharias Machado, Janine Coombes, Robin J Flynn, Gavin J Wright, Andrew P Jackson
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 9, p e0010791 (2022)
Trypanosoma vivax is a unicellular hemoparasite, and a principal cause of animal African trypanosomiasis (AAT), a vector-borne and potentially fatal livestock disease across sub-Saharan Africa. Previously, we identified diverse T. vivax-specific gene
Externí odkaz:
https://doaj.org/article/89483fc1415d498f90bc0e90ff0c6551
Autor:
Porntida Kobpornchai, Robin J Flynn, Onrapak Reamtong, Nonglucksanawan Rittisoonthorn, Nathamon Kosoltanapiwat, Kobporn Boonnak, Usa Boonyuen, Sumate Ampawong, Montakan Jiratanh, Muncharee Tattiyapong, Poom Adisakwattana
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 4, p e0008192 (2020)
Trichinella spiralis can modulate host immune responses to retain a suitable environment for its long-term survival. Incidentally, the parasite elicits regulatory effects through immunomodulatory molecule release, which can suppress host inflammation
Externí odkaz:
https://doaj.org/article/b2662360e15947e5b9b07dd1c20bcefe
Autor:
Azad A Sulaiman, Katarzyna Zolnierczyk, Ornampai Japa, Jonathan P Owen, Ben C Maddison, Richard D Emes, Jane E Hodgkinson, Kevin C Gough, Robin J Flynn
Publikováno v:
PLoS Pathogens, Vol 12, Iss 11, p e1005991 (2016)
The trematode Fasciola hepatica is responsible for chronic zoonotic infection globally. Despite causing a potent T-helper 2 response, it is believed that potent immunomodulation is responsible for rendering this host reactive non-protective host resp
Externí odkaz:
https://doaj.org/article/4346b89fd77c4086a6de70b0779a5c4f
Autor:
Hong Li, Tingli Liu, Yongchun Yang, William C. Cho, Robin J. Flynn, Majid Fasihi Harandi, Houhui Song, Xuenong Luo, Yadong Zheng
Publikováno v:
Genes & Diseases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73751cf9c2c3a68eb3e738925cb506a6
https://doi.org/10.1016/j.gendis.2022.08.013
https://doi.org/10.1016/j.gendis.2022.08.013
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Fasciola hepatica infection of ruminants leads to non-resolving chronic infection, as patency develops, there is switching to a TGF-β and IL-10 led response. Here, we explore the responses of CD4 T-cells within the major draining lymph nodes. We fou
Externí odkaz:
https://doaj.org/article/fff3d05b68bd476cbac1b14d85ae4a5c
Publikováno v:
Parasitology research. 121(12)
Liver flukes, Fasciola spp., are veterinary and medically important parasites infecting numerous species of economically important animals in addition to humans on a global scale. The components of transforming growth factor beta (TGF-β) signalling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab9514025584692cba0d529d9c5b59b8
https://pubmed.ncbi.nlm.nih.gov/36194274
https://pubmed.ncbi.nlm.nih.gov/36194274
Autor:
Alessandra Romero-Ramirez, Aitor Casas-Sánchez, Delphine Autheman, Craig W. Duffy, Marta M. G. Teixeira, Rosangela Z. Machado, Janine Coombes, Robin J. Flynn, Gavin J. Wright, Andrew P. Jackson
Trypanosoma vivaxis a unicellular hemoparasite, and a principal cause of animal African trypanosomiasis (AAT), a vector-borne and potentially fatal disease of livestock across sub-Saharan Africa. Previously, we identified diverseT. vivax-specific gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d177397f524435d97e9f5e5840d797ba
https://doi.org/10.1101/2022.02.16.480502
https://doi.org/10.1101/2022.02.16.480502
Publikováno v:
Microbes and Infection
Microbes and Infection, 2022, 24 (5), pp.104952. ⟨10.1016/j.micinf.2022.104952⟩
Microbes and Infection, 2022, 24 (5), pp.104952. ⟨10.1016/j.micinf.2022.104952⟩
International audience; Toxoplasma gondii infects approximately 1-2 billion people, and manipulation of the macrophage response is critical to host and parasite survival. A cleaved (cl)-CD95L form can promote cellular migration and we have previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d9a83ec90f164a38800770a8be7e9d8
https://hal.science/hal-03632273/document
https://hal.science/hal-03632273/document
Autor:
David M. Haig, Jane E. Hodgkinson, Rebecca C. Hoyle, Robin J. Flynn, Mayowa Musah-Eroje, Ornampai Japa
Publikováno v:
International journal for parasitology. 51(6)
The trematode parasite Fasciola hepatica causes chronic infection in hosts, enabled by an immunosuppressed environment. Both host and parasite factors are known to contribute to this suggesting that avoidance of immunopathology is beneficial to both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d20d766a016dff4e34e07f550fb3e7
https://pubmed.ncbi.nlm.nih.gov/33581140
https://pubmed.ncbi.nlm.nih.gov/33581140
Autor:
Lisa Luu, Janine L. Coombes, Miriam F. Hares, Ellen-Alana Tiffney, Christopher J. Stewart, Luke J. Johnston, Robin J. Flynn
Publikováno v:
Parasite Immunology
Toxoplasma gondii and Cryptosporidium spp. can cause devastating pathological effects in humans and livestock, and in particular to young or immunocompromised individuals. The current treatment plans for these enteric parasites are limited due to lon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19a6a54da0070e049ca02e725b649e5a