Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Robin Hallett"'
Autor:
Branavan Manoranjan, Chitra Venugopal, David Bakhshinyan, Ashley A. Adile, Laura Richards, Michelle M. Kameda-Smith, Owen Whitley, Anna Dvorkin-Gheva, Minomi Subapanditha, Neil Savage, Nazanin Tatari, Dillon McKenna, Blessing Bassey-Archibong, Neil Winegarden, Robin Hallett, John P. Provias, Blake Yarascavitch, Olufemi Ajani, Adam Fleming, Gary D. Bader, Trevor J. Pugh, Bradley W. Doble, Sheila K. Singh
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The Wnt molecular subgroup of medulloblastoma is associated with better prognosis than the other molecular subgroups. Here, the authors show that activating Wnt signaling impairs tumor development and improves survival in Group 3 and Group 4 medullob
Externí odkaz:
https://doaj.org/article/90b86d3d0f9c41078f2e0a70337929d5
Autor:
Meredith S. Irwin, David R. Kaplan, Alexander Gont, Lynn Kee, Yingying Wang, Teresa Adderley, Ivette Valencia-Sama, Robin Hallett, Bo Kyung Alex Seong, Yagnesh Ladumor
Supplementary Figure from Vitamin D Receptor Activation Attenuates Hippo Pathway Effectors and Cell Survival in Metastatic Neuroblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1132604aca1d1ed3a06241b6d66260ec
https://doi.org/10.1158/1541-7786.22527933.v1
https://doi.org/10.1158/1541-7786.22527933.v1
Autor:
Meredith S. Irwin, David R. Kaplan, Alexander Gont, Lynn Kee, Yingying Wang, Teresa Adderley, Ivette Valencia-Sama, Robin Hallett, Bo Kyung Alex Seong, Yagnesh Ladumor
Supplementary Data from Vitamin D Receptor Activation Attenuates Hippo Pathway Effectors and Cell Survival in Metastatic Neuroblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a6e03be192344009885f7284c55dfcf
https://doi.org/10.1158/1541-7786.22527945
https://doi.org/10.1158/1541-7786.22527945
Autor:
Sheila K. Singh, John A. Hassell, Mickie Bhatia, Bradley W. Doble, Naresh K. Murty, Kesava Reddy, John P. Provias, Boleslaw Lach, Thusyanth Vijayakumar, Neha Garg, David Bakhshinyan, Mohini Singh, Sara M. Nolte, Minomi Subapanditha, Nicole McFarlane, Maleeha A. Qazi, Sujeivan Mahendram, Branavan Manoranjan, Parvez Vora, Robin Hallett, Chitra Venugopal
Supplementary Tables 1-6. Supplementary Table 1: Clinico-pathological demographics of CD133high and CD133low GBM; Supplementary Table 2: Positive and negative correlation probe sets present in CD133-signature; Supplementary Table 3: Drug targets acqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de78838d7c2f0c5240df40b3287c5a4a
https://doi.org/10.1158/1078-0432.22461183
https://doi.org/10.1158/1078-0432.22461183
Autor:
Sheila K. Singh, John A. Hassell, Mickie Bhatia, Bradley W. Doble, Naresh K. Murty, Kesava Reddy, John P. Provias, Boleslaw Lach, Thusyanth Vijayakumar, Neha Garg, David Bakhshinyan, Mohini Singh, Sara M. Nolte, Minomi Subapanditha, Nicole McFarlane, Maleeha A. Qazi, Sujeivan Mahendram, Branavan Manoranjan, Parvez Vora, Robin Hallett, Chitra Venugopal
Supplementary Figures 1-6. Supplementary Figure 1: CD133 correlates patient outcome with GIC selfrenewal and proliferative capacities in human GBM; Supplementary Figure 2: Gene Set Enrichment Analysis (GSEA) results for embryonic stem cell gene sets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681815f4a53c686ab94a8ae9200b1e5d
https://doi.org/10.1158/1078-0432.22461186.v1
https://doi.org/10.1158/1078-0432.22461186.v1
Autor:
Sheila K. Singh, John A. Hassell, Mickie Bhatia, Bradley W. Doble, Naresh K. Murty, Kesava Reddy, John P. Provias, Boleslaw Lach, Thusyanth Vijayakumar, Neha Garg, David Bakhshinyan, Mohini Singh, Sara M. Nolte, Minomi Subapanditha, Nicole McFarlane, Maleeha A. Qazi, Sujeivan Mahendram, Branavan Manoranjan, Parvez Vora, Robin Hallett, Chitra Venugopal
Purpose: Clonal evolution of cancer may be regulated by determinants of stemness, specifically self-renewal, and current therapies have not considered how genetic perturbations or properties of stemness affect such functional processes. Glioblastoma-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd1dfd8b7def7e3e289f754346e8c43
https://doi.org/10.1158/1078-0432.c.6524712
https://doi.org/10.1158/1078-0432.c.6524712
Autor:
David R. Kaplan, Meredith S. Irwin, Cynthia E. Hawkins, Lynn Kee, Samar Mouaaz, Lincoln D. Stein, Christina K. Yung, Robin Hallett, Kelly E. Fathers, Bo Kyung A. Seong
Metastatic relapse is the major cause of death in pediatric neuroblastoma, where there remains a lack of therapies to target this stage of disease. To understand the molecular mechanisms mediating neuroblastoma metastasis, we developed a mouse model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ee57c53564def9917ee6fb51d72a21f
https://doi.org/10.1158/0008-5472.c.6509016.v1
https://doi.org/10.1158/0008-5472.c.6509016.v1
Autor:
David R. Kaplan, Meredith S. Irwin, Cynthia E. Hawkins, Lynn Kee, Samar Mouaaz, Lincoln D. Stein, Christina K. Yung, Robin Hallett, Kelly E. Fathers, Bo Kyung A. Seong
Further details of materials & methods provided in supplementary data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::413784f8d6dec04f4d29506eb5d789e5
https://doi.org/10.1158/0008-5472.22414536
https://doi.org/10.1158/0008-5472.22414536
Autor:
David R. Kaplan, Meredith S. Irwin, Cynthia E. Hawkins, Lynn Kee, Samar Mouaaz, Lincoln D. Stein, Christina K. Yung, Robin Hallett, Kelly E. Fathers, Bo Kyung A. Seong
Legends for Supplementary figures are provided
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::261542dd37447e35c181f49df15a60e9
https://doi.org/10.1158/0008-5472.22414542.v1
https://doi.org/10.1158/0008-5472.22414542.v1
Autor:
David R. Kaplan, Meredith S. Irwin, Cynthia E. Hawkins, Lynn Kee, Samar Mouaaz, Lincoln D. Stein, Christina K. Yung, Robin Hallett, Kelly E. Fathers, Bo Kyung A. Seong
Supplementary Figure 1 - The metastatic subpopulations display enhanced metastatic burden relative to the SK-N-AS-TR parental cell line in vivo and increased chemoresistance in vitro. Supplementary Figure 2 - GSEA enrichment map show signaling pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac0029b54dba442ad7595f8d2dc83024
https://doi.org/10.1158/0008-5472.22414539.v1
https://doi.org/10.1158/0008-5472.22414539.v1