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pro vyhledávání: '"Robin Groen"'
Autor:
Edo Vellenga, Robin Groen, Huipin Yuan, Jennifer Jaques, Jan Jacob Schuringa, J. D. de Bruijn, Anton C. M. Martens, Pallavi Sontakke, Linda Lubbers-Aalders, Annet Z. Brouwers-Vos, Marco Carretta
Publikováno v:
Leukemia, 30(10), 2064-2073. Nature Publishing Group
Sontakke, P, Carretta, M, Jaques, J, Brouwers-Vos, A Z, Lubbers-Aalders, L, Yuan, H, de Bruijn, J D, Martens, A C M, Vellenga, E, Groen, R W J & Schuringa, J J 2016, ' Modeling BCR-ABL and MLL-AF9 leukemia in a human bone marrow-like scaffold-based xenograft model ', Leukemia, vol. 30, no. 10, pp. 2064-2073 . https://doi.org/10.1038/leu.2016.108
Sontakke, P, Carretta, M, Jaques, J, Brouwers-Vos, A Z, Lubbers-Aalders, L, Yuan, H, de Bruijn, J D, Martens, A C M, Vellenga, E, Groen, R W J & Schuringa, J J 2016, ' Modeling BCR-ABL and MLL-AF9 leukemia in a human bone marrow-like scaffold-based xenograft model ', Leukemia, vol. 30, no. 10, pp. 2064-2073 . https://doi.org/10.1038/leu.2016.108
Although NOD-SCID IL2R gamma(-/-) (NSG) xenograft mice are currently the most frequently used model to study human leukemia in vivo, the absence of a human niche severely hampers faithful recapitulation of the disease. We used NSG mice in which ceram