Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Robin Goland"'
Autor:
Janine Higgins, Philip Zeitler, Kimberly L. Drews, Silva Arslanian, Kenneth Copeland, Robin Goland, Georgeanna Klingensmith, Terri H. Lipman, Sherida Tollefsen
Publikováno v:
Journal of Clinical & Translational Endocrinology, Vol 29, Iss , Pp 100300- (2022)
Aim: ZnT8 autoantibody positivity (ZnT8+) is associated with risk for type 1 diabetes and with metabolic complications in adults. Our aim was to assess prevalence of ZnT8 + in the Treatment of T2D in Adolescents and Youth (TODAY) cohort and describe
Externí odkaz:
https://doaj.org/article/be161448c3c545e18b73387a0fb1a3a0
Autor:
Carla J. Greenbaum, Elisavet Serti, Katharina Lambert, Lia J. Weiner, Sai Kanaparthi, Sandra Lord, Stephen E. Gitelman, Darrell M. Wilson, Jason L. Gaglia, Kurt J. Griffin, William E. Russell, Philip Raskin, Antoinette Moran, Steven M. Willi, Eva Tsalikian, Linda A. DiMeglio, Kevan C. Herold, Wayne V. Moore, Robin Goland, Mark Harris, Maria E. Craig, Desmond A. Schatz, David A. Baidal, Henry Rodriguez, Kristina M. Utzschneider, Hendrik J. Nel, Carol L. Soppe, Karen D. Boyle, Karen Cerosaletti, Lynette Keyes-Elstein, S. Alice Long, Ranjeny Thomas, James G. McNamara, Jane H. Buckner, Srinath Sanda, for the ITN058AI EXTEND Study Team
Publikováno v:
JCI Insight, Vol 6, Iss 21 (2021)
Background IL-6 receptor (IL-6R) signaling drives development of T cell populations important to type 1 diabetes pathogenesis. We evaluated whether blockade of IL-6R with monoclonal antibody tocilizumab would slow loss of residual β cell function in
Externí odkaz:
https://doaj.org/article/083a57294536479793c92cf07ad43e13
Autor:
Chiara Borsotti, Nichole M. Danzl, Grace Nauman, Markus A. Hölzl, Clare French, Estefania Chavez, Mohsen Khosravi-Maharlooei, Salome Glauzy, Fabien R. Delmotte, Eric Meffre, David G. Savage, Sean R. Campbell, Robin Goland, Ellen Greenberg, Jing Bi, Prakash Satwani, Suxiao Yang, Joan Bathon, Robert Winchester, Megan Sykes
Publikováno v:
Blood Advances, Vol 1, Iss 23, Pp 2007-2018 (2017)
Abstract: B cells play a major role in antigen presentation and antibody production in the development of autoimmune diseases, and some of these diseases disproportionally occur in females. Moreover, immune responses tend to be stronger in female vs
Externí odkaz:
https://doaj.org/article/72da05736802495ebfbfad73ddbd936c
Autor:
Robin Goland, Dieter Egli
Publikováno v:
EBioMedicine, Vol 1, Iss 2, Pp 93-94 (2014)
Externí odkaz:
https://doaj.org/article/66042efce56d45cd87b04b2653c3be7f
Autor:
Kellee M, Miller, Lauren G, Kanapka, Michael R, Rickels, Andrew J, Ahmann, Grazia, Aleppo, Lynn, Ang, Anuj, Bhargava, Bruce W, Bode, Anders, Carlson, Naomi S, Chaytor, Gail, Gannon, Robin, Goland, Irl B, Hirsch, Lisa, Kiblinger, Davida, Kruger, Yogish C, Kudva, Carol J, Levy, Janet B, McGill, Grenye, O'Malley, Anne L, Peters, Louis H, Philipson, Athena, Philis-Tsimikas, Rodica, Pop-Busui, Maamoun, Salam, Viral N, Shah, Michael J, Thompson, Francesco, Vendrame, Alandra, Verdejo, Ruth S, Weinstock, Laura, Young, Richard, Pratley
Publikováno v:
Diabetes Technol Ther
OBJECTIVE: To evaluate glycemic outcomes in the Wireless Innovation for Seniors with Diabetes Mellitus (WISDM) randomized clinical trial (RCT) participants during an observational extension phase. RESEARCH DESIGN AND METHODS: WISDM RCT was a 26-week
Autor:
Steven J, Russell, Roy W, Beck, Edward R, Damiano, Firas H, El-Khatib, Katrina J, Ruedy, Courtney A, Balliro, Zoey, Li, Peter, Calhoun, R Paul, Wadwa, Bruce, Buckingham, Keren, Zhou, Mark, Daniels, Philip, Raskin, Perrin C, White, Jane, Lynch, Jeremy, Pettus, Irl B, Hirsch, Robin, Goland, John B, Buse, Davida, Kruger, Nelly, Mauras, Andrew, Muir, Janet B, McGill, Fran, Cogen, Jill, Weissberg-Benchell, Jordan S, Sherwood, Luz E, Castellanos, Mallory A, Hillard, Marwa, Tuffaha, Melissa S, Putman, Mollie Y, Sands, Gregory, Forlenza, Robert, Slover, Laurel H, Messer, Erin, Cobry, Viral N, Shah, Sarit, Polsky, Rayhan, Lal, Laya, Ekhlaspour, Michael S, Hughes, Marina, Basina, Betul, Hatipoglu, Leann, Olansky, Amrit, Bhangoo, Nikta, Forghani, Himala, Kashmiri, Francoise, Sutton, Abha, Choudhary, Jimmy, Penn, Rabab, Jafri, Maria, Rayas, Elia, Escaname, Catherine, Kerr, Ruby, Favela-Prezas, Schafer, Boeder, Subbulaxmi, Trikudanathan, Kristen M, Williams, Natasha, Leibel, M Sue, Kirkman, Kate, Bergamo, Klara R, Klein, Jean M, Dostou, Sriram, Machineni, Laura A, Young, Jamie C, Diner, Arti, Bhan, J Kimberly, Jones, Matthew, Benson, Keisha, Bird, Kimberly, Englert, Joe, Permuy, Kristina, Cossen, Eric, Felner, Maamoun, Salam, Julie M, Silverstein, Samantha, Adamson, Andrea, Cedeno, Seema, Meighan, Carol, Wysham
Publikováno v:
The New England journal of medicine. 387(13)
Currently available semiautomated insulin-delivery systems require individualized insulin regimens for the initialization of therapy and meal doses based on carbohydrate counting for routine operation. In contrast, the bionic pancreas is initialized
Publikováno v:
Diabetes Care
OBJECTIVE Insulin secretion declines rapidly after diagnosis of type 1 diabetes, followed by a slower rate of change. Previous studies have demonstrated that the C-peptide decline begins before the clinical diagnosis. Changes in insulin secretion in
Autor:
Antoinette Moran, S. Alice Long, Philip Raskin, James McNamara, William E. Russell, Carol L. Soppe, Sai Kanaparthi, Elisavet Serti, Hendrik J. Nel, Kevan C. Herold, Sandra Lord, Lia J Weiner, Steven M. Willi, Lynette Keyes-Elstein, Kurt J Griffin, Robin Goland, Ranjeny Thomas, Stephen E. Gitelman, Mark Harris, Henry Rodriguez, Karen Cerosaletti, Linda A. DiMeglio, Darrell M. Wilson, Itn Ai Extend Study Team, Wayne V. Moore, Srinath Sanda, Carla J. Greenbaum, Maria E. Craig, David A. Baidal, Kristina M. Utzschneider, Jason L. Gaglia, Katharina Lambert, Eva Tsalikian, Karen D. Boyle, Desmond A. Schatz, Jane H. Buckner
Publikováno v:
JCI Insight
JCI insight, vol 6, iss 21
JCI insight, vol 6, iss 21
Background IL-6 receptor (IL-6R) signaling drives development of T cell populations important to type 1 diabetes pathogenesis. We evaluated whether blockade of IL-6R with monoclonal antibody tocilizumab would slow loss of residual β cell function in
Autor:
Haoquan Zhao, Rudolph Leibel, Christopher N Goulbourne, Jose Oberholzer, Jaeyop Lee, Yufeng Shen, Yuan Xing, Damian J. Williams, Robin Goland, Jesper Gromada, Henry M. Colecraft, Charles A. LeDuc, Jacqueline Niu, Xiajuan Chen, Wendy K. Chung, Dieter Egli, Yong Wang, Bryan J. González
Mutations in HNF1A cause Maturity Onset Diabetes of the Young type 3 (MODY3), the most prevalent form of monogenic diabetes. Using stem cell-derived pancreatic endocrine cells from human embryonic stem cells (hESCs) with induced hypomorphic mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::565b155cffa400ec721706fdf1ec43eb
https://doi.org/10.21203/rs.3.rs-509878/v1
https://doi.org/10.21203/rs.3.rs-509878/v1
Autor:
Antoinette Moran, S. Alice Long, Susan Geyer, Megan V. Warnock, Linda A. DiMeglio, Henry Rodriguez, Jennifer B. Marks, Dorothy J. Becker, David A. Baidal, J Lori Blanchfield, Darrell M. Wilson, Peter A. Gottlieb, Stephen E. Gitelman, Desmond A. Schatz, Brian N. Bundy, Jessica L. Miller, Mark A. Atkinson, Michael J. Haller, Jay S. Skyler, Carla J. Greenbaum, Robin Goland, Jeffrey P. Krischer, Kevan C. Herold, William E. Russell
Publikováno v:
Diabetes
A three-arm, randomized, double-masked, placebo-controlled phase 2b trial performed by the Type 1 Diabetes TrialNet Study Group previously demonstrated that low-dose anti-thymocyte globulin (ATG) (2.5 mg/kg) preserved β-cell function and reduced HbA