Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Robin Elgart"'
Autor:
Hari Ilangovan, Prachi Kothiyal, Katherine A. Hoadley, Robin Elgart, Greg Eley, Parastou Eslami
Publikováno v:
npj Microgravity, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract NASA has employed high-throughput molecular assays to identify sub-cellular changes impacting human physiology during spaceflight. Machine learning (ML) methods hold the promise to improve our ability to identify important signals within hig
Externí odkaz:
https://doaj.org/article/39da41b7f01e4edd933e42973a4e7fff
Autor:
Prachi Kothiyal, Greg Eley, Hari Ilangovan, Katherine A. Hoadley, S. Robin Elgart, Xiao W. Mao, Parastou Eslami
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The space environment includes unique hazards like radiation and microgravity which can adversely affect biological systems. We assessed a multi-omics NASA GeneLab dataset where mice were hindlimb unloaded and/or gamma irradiated for 21 days
Externí odkaz:
https://doaj.org/article/8ed98ba55da94445a67f693e1a852a10
Autor:
Keisuke S. Iwamoto, PhD, Robert E. Sandstrom, MD, Mark Bryan, EdM, Yue Liu, PhD, S. Robin Elgart, PhD, Ke Sheng, PhD, Michael L. Steinberg, MD, William H. McBride, DSc, Daniel A. Low, PhD
Publikováno v:
Advances in Radiation Oncology, Vol 6, Iss 3, Pp 100645- (2021)
Purpose: The clinical efficacy of radiation therapy is mechanistically linked to ionization-induced free radicals that cause cell and tissue injury through direct and indirect mechanisms. Free radical reaction dynamics are influenced by many factors
Externí odkaz:
https://doaj.org/article/09bd2ef75e0c48eaba3967ae6c9af553
Autor:
Norbury, John W., Schimmerling, Walter, Slaba, Tony C., Azzam, Edouard I., Badavi, Francis F., Baiocco, Giorgio, Benton, Eric, Bindi, Veronica, Blakely, Eleanor A., Blattnig, Steve R., Boothman, David A., Borak, Thomas B., Britten, Richard A., Curtis, Stan, Dingfelder, Michael, Durante, Marco, Dynan, William S., Eisch, Amelia J., Robin Elgart, S., Goodhead, Dudley T., Guida, Peter M., Heilbronn, Lawrence H., Hellweg, Christine E., Huff, Janice L., Kronenberg, Amy, La Tessa, Chiara, Lowenstein, Derek I., Miller, Jack, Morita, Takashi, Narici, Livio, Nelson, Gregory A., Norman, Ryan B., Ottolenghi, Andrea, Patel, Zarana S., Reitz, Guenther, Rusek, Adam, Schreurs, Ann-Sofie, Scott-Carnell, Lisa A., Semones, Edward, Shay, Jerry W., Shurshakov, Vyacheslav A., Sihver, Lembit, Simonsen, Lisa C., Story, Michael D., Turker, Mitchell S., Uchihori, Yukio, Williams, Jacqueline, Zeitlin, Cary J.
Publikováno v:
In Life Sciences in Space Research February 2016 8:38-51
Publikováno v:
Radiation Research.
Prediction of cancer risk from space radiation exposure is critical to ensure spaceflight crewmembers are adequately informed of the risks they face when accepting assignments to ambitious long-duration exploratory missions. Although epidemiological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0974a8462edbfd004893970ae693992
https://doi.org/10.1667/rade-22-00176.1
https://doi.org/10.1667/rade-22-00176.1
Autor:
Brock J. Sishc, Janice Zawaski, Janapriya Saha, Lisa S. Carnell, Kristin M. Fabre, S. Robin Elgart
Publikováno v:
Life sciences in space research. 35
NASA's currently planned long-duration, deep space exploration missions outside of low Earth orbit (LEO) will result in the exposure of astronauts to relatively high lifetime doses of ionizing radiation (IR), exceeding what humans have previously enc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d2199580484cbd24e95707aafff487
https://pubmed.ncbi.nlm.nih.gov/36336368
https://pubmed.ncbi.nlm.nih.gov/36336368
Publikováno v:
Handbook of Lunar Base Design and Development ISBN: 9783030053239
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7161d0c159d06554f4906f2cd0235b46
https://doi.org/10.1007/978-3-030-05323-9_4-1
https://doi.org/10.1007/978-3-030-05323-9_4-1
Autor:
Robert E. Sandstrom, S. Robin Elgart, Michael L. Steinberg, Daniel A. Low, Ke Sheng, William H. McBride, Mark Bryan, Yue Liu, Keisuke S. Iwamoto
Publikováno v:
Advances in Radiation Oncology, Vol 6, Iss 3, Pp 100645-(2021)
Advances in Radiation Oncology
Advances in radiation oncology, vol 6, iss 3
Advances in Radiation Oncology
Advances in radiation oncology, vol 6, iss 3
Purpose The clinical efficacy of radiation therapy is mechanistically linked to ionization-induced free radicals that cause cell and tissue injury through direct and indirect mechanisms. Free radical reaction dynamics are influenced by many factors a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b37f75463e44684d5c5da414a9fdecbf
http://www.sciencedirect.com/science/article/pii/S2452109421000038
http://www.sciencedirect.com/science/article/pii/S2452109421000038
Publikováno v:
Radiation research. 194(1)
Recently reported studies considering nonlinearity in the effects of low-dose space radiation have assumed a nontargeted mechanism. To date, few analyses have been performed to assess whether a nontargeted term is supported by the available data. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab3d83077bbeeeed9d84f3c039cbf7d8
https://pubmed.ncbi.nlm.nih.gov/32330076
https://pubmed.ncbi.nlm.nih.gov/32330076
Autor:
Mark P. Little, Zarana S. Patel, Lori J. Chappell, Mark R. Shavers, Janice L. Huff, Caitlin M. Milder, S. Robin Elgart
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reports
Scientific Reports
Understanding space radiation health effects is critical due to potential increased morbidity and mortality following spaceflight. We evaluated whether there is evidence for excess cardiovascular disease or cancer mortality in early NASA astronauts a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd5feda4484e14f6d805fc54f90e0587
https://doi.org/10.1038/s41598-018-25467-9
https://doi.org/10.1038/s41598-018-25467-9