Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Robin Eichmiller"'
Autor:
Ja-Hwan Seol, Cory Holland, Xiaolei Li, Christopher Kim, Fuyang Li, Melisa Medina-Rivera, Robin Eichmiller, Ignacio F. Gallardo, Ilya J. Finkelstein, Paul Hasty, Eun Yong Shim, Jennifer A. Surtees, Sang Eun Lee
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The yeast Rad1–Rad10 complex has multiple roles in DNA damage repair. Here the authors uncover mutants that uncouple the roles in UV excision repair and non-NER functions.
Externí odkaz:
https://doaj.org/article/1aa8a55b041d446c9bd15181548a0127
Autor:
Robin Eichmiller, Jennifer A. Surtees, Christopher Kim, Ja Hwan Seol, Melisa Medina-Rivera, Cory Holland, Ignacio F. Gallardo, Diane Oramus, Rachel DeSanto, Jessica Smith, Eugen Minca, Sang Eun Lee, Megan Schmit, Ilya J. Finkelstein
Publikováno v:
Nucleic Acids Research
Double strand DNA break repair (DSBR) comprises multiple pathways. A subset of DSBR pathways, including single strand annealing, involve intermediates with 3′ non-homologous tails that must be removed to complete repair. In Saccharomyces cerevisiae
Autor:
Cory Holland, Fuyang Li, Ja Hwan Seol, Robin Eichmiller, Melisa Medina-Rivera, Christopher Kim, Ignacio F. Gallardo, Jennifer A. Surtees, Paul Hasty, Xiaolei Li, Ilya J. Finkelstein, Eun Yong Shim, Sang Eun Lee
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Yeast Rad1–Rad10 (XPF–ERCC1 in mammals) incises UV, oxidation, and cross-linking agent-induced DNA lesions, and contributes to multiple DNA repair pathways. To determine how Rad1–Rad10 catalyzes inter-strand crosslink repair (ICLR), we examined
Autor:
Rohit Prakash, Junachao Dong, Eun Yong Shim, Patrick Sung, Fuyang Li, Robin Eichmiller, Cory Holland, Jennifer A. Surtees, Sang Eun Lee, Eugen Minca
Publikováno v:
The EMBO Journal. 32:461-472
The Saccharomyces cerevisiae Rad1/Rad10 complex is a multifunctional, structure-specific endonuclease that processes UV-induced DNA lesions, recombination intermediates, and inter-strand DNA crosslinks. However, we do not know how Rad1/Rad10 recogniz
Autor:
Jennifer A. Surtees, Piero R. Bianco, Gregory M. Williams, Bangchen Wang, Robin Eichmiller, Charanya Kumar
Publikováno v:
DNA repair. 18
In Saccharomyces cerevisiae, Msh2-Msh3-mediated mismatch repair (MMR) recognizes and targets insertion/deletion loops for repair. Msh2-Msh3 is also required for 3′ non-homologous tail removal (3′NHTR) in double-strand break repair. In both pathwa