Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Robin Duelen"'
Autor:
Domiziana Costamagna, Valeria Bastianini, Marlies Corvelyn, Robin Duelen, Jorieke Deschrevel, Nathalie De Beukelaer, Hannah De Houwer, Maurilio Sampaolesi, Ghislaine Gayan-Ramirez, Anja Van Campenhout, Kaat Desloovere
Publikováno v:
Cells, Vol 12, Iss 16, p 2072 (2023)
Botulinum neurotoxin type-A (BoNT) injections are commonly used as spasticity treatment in cerebral palsy (CP). Despite improved clinical outcomes, concerns regarding harmful effects on muscle morphology have been raised, and the BoNT effect on muscl
Externí odkaz:
https://doaj.org/article/ffe2c6984d534492bdb88539d30e63fa
Autor:
Marc Beltrà, Fabrizio Pin, Domiziana Costamagna, Robin Duelen, Alessandra Renzini, Riccardo Ballarò, Lorena Garcia-Castillo, Ambra Iannuzzi, Viviana Moresi, Dario Coletti, Maurilio Sampaolesi, Fabio Penna, Paola Costelli
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105480- (2022)
Summary: Skeletal muscle repair is accomplished by satellite cells (MuSCs) in cooperation with interstitial stromal cells (ISCs), but the relationship between the function of these cells and the metabolic state of myofibers remains unclear. This stud
Externí odkaz:
https://doaj.org/article/d23a3e4def1d4333a183327d1e23d406
Autor:
Vittoria Marini, Fabiola Marino, Flaminia Aliberti, Nefele Giarratana, Enrico Pozzo, Robin Duelen, Álvaro Cortés Calabuig, Rita La Rovere, Tim Vervliet, Daniele Torella, Geert Bultynck, Maurilio Sampaolesi, Yoke Chin Chai
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Duchenne Muscular Dystrophy (DMD) is an X-linked neuromuscular disease which to date is incurable. The major cause of death is dilated cardiomyopathy however, its pathogenesis is unclear as existing cellular and animal models do not fully recapitulat
Externí odkaz:
https://doaj.org/article/e1250935e81c483f8fd7d6f1e6ccda3f
Autor:
Domiziana Costamagna, Robin Duelen, Fabio Penna, Detlef Neumann, Paola Costelli, Maurilio Sampaolesi
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 3, Pp 783-801 (2020)
Abstract Background Anorexia, body wasting, inflammation, muscle, and adipose tissue loss are hallmarks of cancer cachexia, a syndrome that affects the majority of cancer patients, impairing their ability to endure chemotherapeutic therapies and redu
Externí odkaz:
https://doaj.org/article/72d4e09cf61844cebcb3d9037f667760
Autor:
Leire Casas-Fraile, Frederique M. Cornelis, Domiziana Costamagna, Anabel Rico, Robin Duelen, Maurilio M. Sampaolesi, Adolfo López de Munain, Rik J. Lories, Amets Sáenz
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-18 (2020)
Abstract Background Limb-girdle muscular dystrophy recessive 1 calpain3-related (LGMDR1), previously known as LGMD2A, is a disease caused by mutations in the CAPN3 gene. It is characterized by progressive weakness and muscle degeneration. Frizzled re
Externí odkaz:
https://doaj.org/article/5f3946e625b847ba8cc43717179513b4
Autor:
Guillaume Gilbert, Chandan Kadur Nagaraju, Robin Duelen, Matthew Amoni, Pierre Bobin, Thomas Eschenhagen, H. Llewelyn Roderick, Maurilio Sampaolesi, Karin R. Sipido
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Human induced pluripotent stem cells derived cardiomyocytes (hiPSC-CM) are increasingly used to study genetic diseases on a human background. However, the lack of a fully mature adult cardiomyocyte phenotype of hiPSC-CM may be limiting the scope of t
Externí odkaz:
https://doaj.org/article/b35c150cb7c84d46b27ae8cd2dd0d249
Autor:
Domiziana Costamagna, Valérie Casters, Marc Beltrà, Maurilio Sampaolesi, Anja Van Campenhout, Els Ortibus, Kaat Desloovere, Robin Duelen
Publikováno v:
Cells, Vol 11, Iss 21, p 3351 (2022)
Hereditary spastic paraplegia (HSP) is a heterogeneous group of genetic neurodegenerative disorders, characterized by progressive lower limb spasticity and weakness resulting from retrograde axonal degeneration of motor neurons (MNs). Here, we genera
Externí odkaz:
https://doaj.org/article/0240023bdbda4090a978318f83fee318
Autor:
Marlies Corvelyn, Nathalie De Beukelaer, Robin Duelen, Jorieke Deschrevel, Anja Van Campenhout, Sandra Prinsen, Ghislaine Gayan-Ramirez, Karen Maes, Guido Weide, Kaat Desloovere, Maurilio Sampaolesi, Domiziana Costamagna
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Cerebral palsy (CP), the single largest cause of childhood physical disability, is characterized firstly by a lesion in the immature brain, and secondly by musculoskeletal problems that progress with age. Previous research reported altered muscle pro
Externí odkaz:
https://doaj.org/article/9a0d3f59d3984f92b7f8851955d14b3b
Autor:
Robin Duelen, Maurilio Sampaolesi
Publikováno v:
EBioMedicine, Vol 16, Iss C, Pp 30-40 (2017)
Despite advances in cardiovascular biology and medical therapy, heart disorders are the leading cause of death worldwide. Cell-based regenerative therapies become a promising treatment for patients affected by heart failure, but also underline the ne
Externí odkaz:
https://doaj.org/article/c31ee33807e749bb901773a6cfe739ba
Autor:
Robin Duelen, Guillaume Gilbert, Abdulsamie Patel, Nathalie de Schaetzen, Liesbeth De Waele, Llewelyn Roderick, Karin R. Sipido, Catherine M. Verfaillie, Gunnar M. Buyse, Lieven Thorrez, Maurilio Sampaolesi
Publikováno v:
Stem Cells International, Vol 2017 (2017)
The use of human pluripotent stem cells in basic and translational cardiac research requires efficient differentiation protocols towards cardiomyocytes. In vitro differentiation yields heterogeneous populations of ventricular-, atrial-, and nodal-lik
Externí odkaz:
https://doaj.org/article/ec180802ac9541a284ff1e0893a521e1