Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Robin Diekmann"'
Autor:
Hong Mao, Karolina Szafranska, Larissa Kruse, Christopher Holte, Deanna L. Wolfson, Balpreet Singh Ahluwalia, Cynthia B. Whitchurch, Louise Cole, Glen P. Lockwood, Robin Diekmann, David Le Couteur, Victoria C. Cogger, Peter A. G. McCourt
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Xanthines such as caffeine and theobromine are among the most consumed psychoactive stimulants in the world, either as natural components of coffee, tea and chocolate, or as added ingredients. The present study assessed if xanthines affect l
Externí odkaz:
https://doaj.org/article/89a927030b4649c98ea7c2897d8f8c7f
Autor:
Robin Diekmann, Joran Deschamps, Yiming Li, Takahiro Deguchi, Aline Tschanz, Maurice Kahnwald, Ulf Matti, Jonas Ries
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Pixel-to-pixel variations in sCMOS cameras lead to image artifacts in widefield fluorescence microscopy, and algorithmic corrections require thorough camera characterization. Here, the authors present an open source automated pipeline for camera char
Externí odkaz:
https://doaj.org/article/7d6a053224ba45d3860133f884414519
Autor:
Arash Ahmadi, Katharina Till, Paul Hoff Backe, Pernille Blicher, Robin Diekmann, Mark Schüttpelz, Kyrre Glette, Jim Tørresen, Magnar Bjørås, Alexander D. Rowe, Bjørn Dalhus
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-8 (2021)
Ahmadi et al. use a single-molecule tracking method to describe the DNA scanning mode of AlkD, a HEAT-like repeat DNA glycosylase. They show that, contrary to other glycosylases that use a base-flipping mechanism, AlkD scans the DNA without forming a
Externí odkaz:
https://doaj.org/article/dc979ac48443432c9defb5314d98f0c6
Autor:
Sara Elfarrash, Nanna Møller Jensen, Nelson Ferreira, Cristine Betzer, Jervis Vermal Thevathasan, Robin Diekmann, Mohamed Adel, Nisreen Mansour Omar, Mohamed Z. Boraie, Sabry Gad, Jonas Ries, Deniz Kirik, Sadegh Nabavi, Poul Henning Jensen
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-16 (2019)
Abstract Here we describe the use of an organotypic hippocampal slice model for studying α-synuclein aggregation and inter-neuronal spreading initiated by microinjection of pre-formed α-synuclein fibrils (PFFs). PFF injection at dentate gyrus (DG)
Externí odkaz:
https://doaj.org/article/10fb2dc993f841539e1e8dae921a245c
Autor:
Arash Ahmadi, Ida Rosnes, Pernille Blicher, Robin Diekmann, Mark Schüttpelz, Kyrre Glette, Jim Tørresen, Magnar Bjørås, Bjørn Dalhus, Alexander D. Rowe
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
How DNA repair proteins locate their target sites on DNA is still a matter of debate. Here the authors characterize by single-molecule fluorescence imaging the modes of scanning adopted by bacterial endonuclease V as it moves along linear DNA tracks.
Externí odkaz:
https://doaj.org/article/731b5efe4af24923bd07d7a709bb4c09
Autor:
Robin Diekmann, Deanna L. Wolfson, Christoph Spahn, Mike Heilemann, Mark Schüttpelz, Thomas Huser
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
Nanoscopy of non-adherent cells is currently not possible, due to their movement in solution. Here the authors immobilize and manipulate fixedE. coli by multiple optical traps; their holographic optical tweezers enable dSTORM imaging of orthogonal pl
Externí odkaz:
https://doaj.org/article/be65c9e7bbcf48d7ae037333ae9ed12a
Publisher Correction: Breaking the speed limit with multimode fast scanning of DNA by Endonuclease V
Autor:
Arash Ahmadi, Ida Rosnes, Pernille Blicher, Robin Diekmann, Mark Schüttpelz, Kyrre Glette, Jim Tørresen, Magnar Bjørås, Bjørn Dalhus, Alexander D. Rowe
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
The original version of this Article was updated shortly after publication to add a link to the Peer Review file, which was inadvertently omitted. The Peer Review file is available to download as a Supplementary File from the HTML version of the Arti
Externí odkaz:
https://doaj.org/article/82393651416948479d663113a88be077
Autor:
Pernille Blicher, Katharina Till, Robin Diekmann, Kyrre Glette, Mark Schüttpelz, Paul Hoff Backe, Magnar Bjørås, Jim Torresen, Bjørn Dalhus, Alexander D. Rowe, Arash Ahmadi
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-8 (2021)
Communications Biology
Communications Biology
The multi-step base excision repair (BER) pathway is initiated by a set of enzymes, known as DNA glycosylases, able to scan DNA and detect modified bases among a vast number of normal bases. While DNA glycosylases in the BER pathway generally bend th
Autor:
Ida Rosnes, Kyrre Glette, Alexander D. Rowe, Robin Diekmann, Bjørn Dalhus, Magnar Bjørås, Arash Ahmadi, Pernille Blicher, Mark Schüttpelz, Jim Torresen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Nature Communications
Nature Communications
In order to preserve genomic stability, cells rely on various repair pathways for removing DNA damage. The mechanisms how enzymes scan DNA and recognize their target sites are incompletely understood. Here, by using high-localization precision micros
Autor:
Yiming Li, Maurice Kahnwald, Ulf Matti, Aline Tschanz, Joran Deschamps, Robin Diekmann, Jonas Ries
Modern implementations of widefield fluorescence microscopy often rely on sCMOS cameras, but this camera architecture inherently features pixel-to-pixel variations. Such variations lead to image artifacts and render quantitative image interpretation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbdf5131eb1e15cae6a281a909b836e5
https://doi.org/10.1101/2021.04.16.440125
https://doi.org/10.1101/2021.04.16.440125