Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Robin D, Couch"'
Autor:
Misgina B. Girma, Haley S. Ball, Xu Wang, Robert C. Brothers, Emily R. Jackson, Marvin J. Meyers, Cynthia S. Dowd, Robin D. Couch
Publikováno v:
ACS Omega, Vol 6, Iss 42, Pp 27630-27639 (2021)
Externí odkaz:
https://doaj.org/article/5f9312837951499b909e15c7c9b48c54
Autor:
Haley S. Ball, Misgina Girma, Mosufa Zainab, Honoria Riley, Christoph T. Behrendt, Claudia Lienau, Sarah Konzuch, Leandro A. A. Avelar, Beate Lungerich, Iswarduth Soojhawon, Schroeder M. Noble, Thomas Kurz, Robin D. Couch
Publikováno v:
ACS Omega, Vol 5, Iss 10, Pp 5170-5175 (2020)
Externí odkaz:
https://doaj.org/article/b4ecf7ff53064ab1aa64dc4e6aca1747
Publikováno v:
Metabolites, Vol 13, Iss 3, p 358 (2023)
Over 33% of Americans are labeled as obese, leading the World Health Organization to designate obesity as a major public health problem. One consequence of obesity is the development of metabolic syndrome, a condition which has been correlated to an
Externí odkaz:
https://doaj.org/article/75c9e6b222e74054ba9c81b4272541eb
Autor:
Iswarduth Soojhawon, Robin D. Couch, Schroeder M. Noble, Mosufa Zainab, Haley Ball, Misgina Girma
Publikováno v:
ACS Infectious Diseases. 7:2987-2998
The ESKAPE pathogens comprise a group of multidrug-resistant bacteria that are the leading cause of nosocomial infections worldwide. The prevalence of antibiotic resistant strains and the relative ease by which bacteria acquire resistance genes highl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d961c7329a8a98ab170901a1207ae2c5
https://doi.org/10.1021/acsinfecdis.1c00132
https://doi.org/10.1021/acsinfecdis.1c00132
Autor:
René Chofor, Martijn D.P. Risseeuw, Jenny Pouyez, Chinchu Johny, Johan Wouters, Cynthia S. Dowd, Robin D. Couch, Serge Van Calenbergh
Publikováno v:
Molecules, Vol 19, Iss 2, Pp 2571-2587 (2014)
Fourteen new fosmidomycin analogues with altered metal chelating groups were prepared and evaluated for inhibition of E. coli Dxr, M. tuberculosis Dxr and the growth of P. falciparum K1 in human erythrocytes. None of the synthesized compounds showed
Externí odkaz:
https://doaj.org/article/8b6c2ff6d29546bab759a0b9b53936b3
Autor:
Beate Lungerich, Claudia Lienau, Haley Ball, Leandro A. Alves Avelar, Christoph T. Behrendt, Mosufa Zainab, Misgina Girma, Iswarduth Soojhawon, Thomas Kurz, Sarah Konzuch, Schroeder M. Noble, Honoria Riley, Robin D. Couch
Publikováno v:
ACS Omega, Vol 5, Iss 10, Pp 5170-5175 (2020)
Fosmidomycin inhibits IspC (1-deoxy-d-xylulose 5-phosphate reductoisomerase), the first committed enzyme in the methylerythritol phosphate (MEP) pathway of isoprenoid biosynthesis. The MEP pathway ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37bda474224e06d850a442e27803d2bd
https://doi.org/10.1021/acsomega.9b04171
https://doi.org/10.1021/acsomega.9b04171
Autor:
Haley S, Ball, Misgina B, Girma, Mosufa, Zainab, Iswarduth, Soojhawon, Robin D, Couch, Schroeder M, Noble
Publikováno v:
ACS infectious diseases. 7(11)
The ESKAPE pathogens comprise a group of multidrug-resistant bacteria that are the leading cause of nosocomial infections worldwide. The prevalence of antibiotic resistant strains and the relative ease by which bacteria acquire resistance genes highl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ebff962ea941640147ac50b738fca5a
https://pubmed.ncbi.nlm.nih.gov/34672535
https://pubmed.ncbi.nlm.nih.gov/34672535
Autor:
Robin D Couch, Allyson Dailey, Fatima Zaidi, Karl Navarro, Christopher B Forsyth, Ece Mutlu, Phillip A Engen, Ali Keshavarzian
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119362 (2015)
Studies have shown that excessive alcohol consumption impacts the intestinal microbiota composition, causing disruption of homeostasis (dysbiosis). However, this observed change is not indicative of the dysbiotic intestinal microbiota function that c
Externí odkaz:
https://doaj.org/article/50135bc6018e4337aa04a8dd8813f8de
Autor:
Amanda Haymond, Chinchu Johny, Tyrone Dowdy, Brandon Schweibenz, Karen Villarroel, Richard Young, Clark J Mantooth, Trishal Patel, Jessica Bases, Geraldine San Jose, Emily R Jackson, Cynthia S Dowd, Robin D Couch
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e106243 (2014)
The methylerythritol phosphate (MEP) pathway found in many bacteria governs the synthesis of isoprenoids, which are crucial lipid precursors for vital cell components such as ubiquinone. Because mammals synthesize isoprenoids via an alternate pathway
Externí odkaz:
https://doaj.org/article/dd1996804d5d44a7a770cf35a3430aee
Autor:
Robin D Couch, Karl Navarro, Masoumeh Sikaroodi, Pat Gillevet, Christopher B Forsyth, Ece Mutlu, Phillip A Engen, Ali Keshavarzian
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81163 (2013)
Recent studies have illustrated the importance of the microbiota in maintaining a healthy state, as well as promoting disease states. The intestinal microbiota exerts its effects primarily through its metabolites, and metabolomics investigations have
Externí odkaz:
https://doaj.org/article/a1de11203b5944ac9079283cb96e852f