Zobrazeno 1 - 10
of 437
pro vyhledávání: '"Robin C, Spiller"'
Autor:
Faiz Alqarni, Tejal Akbar, Hala Fatani, Soma Kumasaka, Caroline L. Hoad, Robin C. Spiller, Moira A. Taylor, Luca Marciani
Publikováno v:
Diagnostics, Vol 14, Iss 19, p 2190 (2024)
Purpose: Knowledge of the length of the colon is relevant to understanding physiological and pathological function. It also has implications for diagnostic and clinical interventions, as well as for the design of delayed-release drug formulations and
Externí odkaz:
https://doaj.org/article/4ffd25e0aac54d2582f70a950286606b
Autor:
Fahad Almutairi, Jaber Alyami, Susan Pritchard, Wala Alsharef, Robin C. Spiller, Penny A. Gowland, Moira A. Taylor, Luca Marciani, Caroline L. Hoad
Publikováno v:
Clinical Nutrition Open Science, Vol 51, Iss , Pp 35-43 (2023)
Summary: The presence of a ‘magenstrasse’, a central ‘stomach road’ for flow and mixing of foods and drinks in the stomach had been predicted from hydrodynamic modelling. Here a magnetic resonance imaging (MRI) tagging technique was used to g
Externí odkaz:
https://doaj.org/article/f98d9193e65041188205539a1800d1a3
Autor:
Hayfa Sharif, Caroline L. Hoad, Nichola Abrehart, Penny A. Gowland, Robin C. Spiller, Sian Kirkham, Sabarinathan Loganathan, Michalis Papadopoulos, Marc A. Benninga, David Devadason, Luca Marciani
Publikováno v:
PLoS ONE, Vol 19, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/639480a865f9413bb01271d29b17784f
Autor:
Khaled Heissam, Nichola Abrehart, Caroline L Hoad, Jeff Wright, Alex Menys, Kathryn Murray, Paul M Glover, Geoffrey Hebbard, Penny A Gowland, Jason Baker, William L Hasler, Robin C Spiller, Maura Corsetti, James G Brasseur, Bart Hens, Kerby Shedden, Joseph Dickens, Deanna M Mudie, Greg E Amidon, Gordon L Amidon, Luca Marciani
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241441 (2020)
ObjectiveThe gastrointestinal environment in which drug products need to disintegrate before the drug can dissolve and be absorbed has not been studied in detail due to limitations, especially invasiveness of existing techniques. Minimal in vivo data
Externí odkaz:
https://doaj.org/article/8b870100c3494f05b33becca50d1d77a
Autor:
Sarah Sulaiman, Pavel Gershkovich, Caroline L. Hoad, Matthew Calladine, Robin C. Spiller, Snow Stolnik, Luca Marciani
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 270 (2022)
Oral specially coated formulations have the potential to improve treatment outcomes of a range of diseases in distal intestinal tract whilst limiting systemic drug absorption and adverse effects. Their development is challenging, partly because of li
Externí odkaz:
https://doaj.org/article/f68c840370fa4199bda136de72ef4c95
Autor:
Meshari T. Alshammari, Ali S. Alyami, Victoria Wilkinson‐Smith, Robin C. Spiller, Penny Gowland, Luca Marciani, Gordon W. Moran, Caroline L. Hoad
Publikováno v:
Neurogastroenterology & Motility.
Autor:
Hayfa Sharif, Caroline L. Hoad, Nichola Abrehart, Penny A. Gowland, Robin C. Spiller, Sian Kirkham, Sabarinathan Loganathan, Michalis Papadopoulos, Marc A. Benninga, David Devadason, Luca Marciani
Publikováno v:
Diagnostics, Vol 11, Iss 6, p 974 (2021)
Background: Functional constipation in children is common. Management of this condition can be challenging and is often based on symptom reports. Increased, objective knowledge of colonic volume changes in constipation compared to health could provid
Externí odkaz:
https://doaj.org/article/a1b1c2fde78342589c01584937040938
Autor:
Kathryn A Murray, Caroline L Hoad, Jill Garratt, Mehri Kaviani, Luca Marciani, Jan K Smith, Britta Siegmund, Penny A Gowland, David J Humes, Robin C Spiller
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216528 (2019)
BackgroundComplications of diverticular disease are increasingly common, possibly linked to increasing obesity. Visceral fat could contribute to the development of symptomatic diverticular disease through its pro-inflammatory effects.ObjectiveThe stu
Externí odkaz:
https://doaj.org/article/f618c143a9824553bb0ae4fb1992d402
Autor:
Asseel Khalaf, Caroline L. Hoad, Elaine Blackshaw, Jaber Alyami, Robin C. Spiller, Penny A. Gowland, Vidhiya Vinayaka-Moorthy, Alan C. Perkins, Gordon W. Moran, Luca Marciani
Publikováno v:
Diagnostics, Vol 10, Iss 3, p 170 (2020)
Measurement of gastric emptying is of clinical value for a range of conditions. Gamma scintigraphy (GS) has an established role, but the use of magnetic resonance imaging (MRI) has recently increased. Previous comparison studies between MRI and GS sh
Externí odkaz:
https://doaj.org/article/b3d88f35f6bc4577b0c7ea37078ba62d
Autor:
Tim J Sloan, Jonna Jalanka, Giles A D Major, Shanthi Krishnasamy, Sue Pritchard, Salah Abdelrazig, Katri Korpela, Gulzar Singh, Claire Mulvenna, Caroline L Hoad, Luca Marciani, David A Barrett, Miranda C E Lomer, Willem M de Vos, Penny A Gowland, Robin C Spiller
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0201410 (2018)
BACKGROUND & AIMS:Ingestion of poorly digested, fermentable carbohydrates (fermentable oligo-, di-, mono-saccharides and polyols; FODMAPs) have been implicated in exacerbating intestinal symptoms and the reduction of intake with symptom alleviation.
Externí odkaz:
https://doaj.org/article/baf301fd890543c188f98ec62f70859a