Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Robin Boineau"'
Autor:
Michael R. Bristow, MD, PhD, Jorge Silva Enciso, MD, Bernard J. Gersh, MB, ChB, DPhil, Christine Grady, RN, PhD, Madeline Murguia Rice, PhD, Steven Singh, MD, George Sopko, MD, MPH, Robin Boineau, MD, MA, Yves Rosenberg, MD, MPH, Barry H. Greenberg, MD
Publikováno v:
JACC: Basic to Translational Science, Vol 1, Iss 3, Pp 180-189 (2016)
TOPCAT (Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist Trial) was a multinational clinical trial of 3,445 heart failure with preserved ejection fraction patients that enrolled in 233 sites in 6 countries in North
Externí odkaz:
https://doaj.org/article/c6cb36e0c635467c9949c7ae20992152
Autor:
Gervasio A. Lamas, Kevin J. Anstrom, Ana Navas-Acien, Robin Boineau, Hwasoon Kim, Yves Rosenberg, Mario Stylianou, Teresa L.Z. Jones, Bonnie R. Joubert, Regina M. Santella, Esteban Escolar, Y. Wady Aude, Vivian Fonseca, Thomas Elliott, Eldrin F. Lewis, Michael E. Farkouh, David M. Nathan, Ana C. Mon, Leigh Gosnell, Jonathan D. Newman, Daniel B. Mark
Publikováno v:
American heart journal. 252
Intravenous edetate disodium-based infusions reduced cardiovascular events in a prior clinical trial. The Trial to Assess Chelation Therapy 2 (TACT2) will replicate the initial study design.TACT2 is an NIH-sponsored, randomized, 2x2 factorial, double
Autor:
Kevin J. Anstrom, Douglas L. Packer, Gust H. Bardy, Jill Anderson, Robin Boineau, Linda Davidson-Ray, Daniel P. Fishbein, Brian Olshansky, Per G. Reinhall, Anne S. Hellkamp, Daniel B. Mark, George Johnson, SCD-HeFT Investigators, Jeanne E. Poole, Kerry L. Lee
Publikováno v:
Journal of the American College of Cardiology. 76:405-415
Background The SCD-HeFT (Sudden Cardiac Death in Heart Failure Trial) randomized 2,521 patients with moderate heart failure (HF) to amiodarone, placebo drug, or implantable cardioverter-defibrillator (ICD) therapy. Original trial follow-up ended Octo
Autor:
Robin Boineau, Gervasio A. Lamas, Daniel B. Mark, Hwasoon Kim, Esteban Escolar, Francisco Ujueta, Kerry L. Lee, Ivan A. Arenas, Lauren Lindblad, Patrick Golden, Denisse Diaz
Publikováno v:
J Diabetes Complications
Objective Approximately 1 in 7 US adults have diabetes; and over 60% of deaths in patients with diabetes have cardiac disease as a principal or contributing cause. Both coronary and peripheral artery disease (PAD) identify high-risk cohorts among pat
Data and Safety Monitoring Board evaluation and management of a renal adverse event signal in TOPCAT
Autor:
Christine Grady, Michael R. Bristow, Sonja M. McKinlay, Robin Boineau, Stuart L. Linas, Barry H. Greenberg, Bernard J. Gersh, Susan F. Assmann, Kavita Sharma, Madeline Murguia Rice, Steven N. Singh
Publikováno v:
European Journal of Heart Failure. 19:457-465
Clinical trial Data and Safety Monitoring Boards (DSMBs) have a primary obligation of ensuring study participant safety, while maintaining trial integrity. The role of DSMBs is expanding, and ideally should include post-hoc reporting of deliberative
Autor:
Christine Goertz, Esteban Escolar, Gervasio A. Lamas, Kerry L. Lee, Daniel B. Mark, Kevin J. Anstrom, Francisco Ujueta, Richard L. Nahin, Robin Boineau, Hwasoon Kim
Publikováno v:
J Diabetes Complications
The NIH-funded Trial to Assess Chelation Therapy (TACT) randomized 1708 stable patients age ≥50 who were ≥6 months post myocardial infarction to 40 infusions of an edetate disodium-based regimen or placebo. In 633 patients with diabetes, edetate
Autor:
Scott D. Solomon, Christopher T. Kenwood, Hae-Young Kim, John A. Spertus, Eldrin F. Lewis, Marc A. Pfeffer, Jerome L. Fleg, Robin Boineau, Carine E. Hamo, John F. Heitner, Susan F. Assmann
Publikováno v:
Circulation: Heart Failure. 8:268-277
Background— Previous studies have demonstrated the psychosocial effect of heart failure in patients with reduced ejection fraction. However, the effects on patients with preserved ejection fraction have not yet been elucidated. This study aimed to
Autor:
Akshay S. Desai, Jean L. Rouleau, John F. Heitner, Sanjiv J. Shah, Nancy K. Sweitzer, Ivan Gordeev, Nadine Oliveira Clausell, Marc A. Pfeffer, Eldrin F. Lewis, Scott D. Solomon, Brian Claggett, Jerome L. Fleg, Tamaz Shaburishvili, Inder S. Anand, Sonja M. McKinlay, Eileen O'Meara, Rafael Diaz, Bertram Pitt, Jeffrey L. Probstfield, Robin Boineau, Susan F. Assmann
Publikováno v:
Circulation. 131:34-42
Background— Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist (TOPCAT) patients with heart failure and preserved left ventricular ejection fraction assigned to spironolactone did not achieve a significant reductio
Autor:
Eileen O'Meara, Inder Anand, Thomas D. Stamos, Nancy K. Sweitzer, James C. Fang, Amil M. Shah, Tamrat M. Retta, John F. Heitner, Bertram Pitt, Jiankang Liu, Marc A. Pfeffer, Eldrin F. Lewis, Jean L. Rouleau, Brian Claggett, Sanjiv J. Shah, Scott D. Solomon, Akshay S. Desai, Robin Boineau
Publikováno v:
Circulation. Heart failure. 11(3)
Background: Black patients have been shown to have different baseline characteristics and outcomes compared with nonblack patients in cohort studies. However, few studies have focused on heart failure (HF) with preserved ejection fraction (HFpEF) pat
Autor:
Jeanne Drisko, Erminia M. Guarneri, Rhonda Roberts, Christine Goertz, Yves Rosenberg, Eldrin F. Lewis, Allan Magaziner, Robin Boineau, Daniel B. Mark, Gervasio A. Lamas, Kerry L. Lee, Omar Issa
Publikováno v:
American heart journal. 195
Importance In a prespecified subgroup analysis of participants not on statin therapy at baseline in the TACT, a high-dose complex oral multivitamins and multimineral regimen was found to have a large unexpected benefit compared with placebo. The regi