Zobrazeno 1 - 10
of 173
pro vyhledávání: '"Robin B. Bedford"'
Publikováno v:
ACS Catalysis. 11:3856-3866
The cobalt-catalyzed Suzuki biaryl cross-coupling of aryl chloride substrates with aryl boron reagents, activated with more commonly used bases, remained a significant unmet challenge in the race t...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3658a0772707618b42ccbbbb0f52a03e
https://doi.org/10.1021/acscatal.0c05557
https://doi.org/10.1021/acscatal.0c05557
Autor:
Sean A. Davis, Pavel S. Kulyabin, Jean-Charles Eloi, Roberto Nolla-Saltiel, Natalie E. Pridmore, Hazel A. Sparkes, Alastair J. J. Lennox, Callum S. Begg, Dietrich Böse, Alexander Z. Voskoboynikov, Matthew O. Kitching, Johannes Krieger, Mickaël Avanthay, Kirill A. Khaikin, Joseph Heeley, Robin B. Bedford, Georgy P. Goryunov, Mark P. Walsh, Ingo Hartung, Benjamin J. S. Rowsell, Dmitry V. Uborsky, Harry J. Wilkinson, Jonathan Clayden
Publikováno v:
Avanthay, M, Bedford, R B, Begg, C S, Böse, D, Clayden, J, Davis, S A, Eloi, J C, Goryunov, G P, Hartung, I V, Heeley, J, Khaikin, K A, Kitching, M O, Krieger, J, Kulyabin, P S, Lennox, A J J, Nolla-Saltiel, R, Pridmore, N E, Rowsell, B J S, Sparkes, H A, Uborsky, D V, Voskoboynikov, A Z, Walsh, M P & Wilkinson, H J 2021, ' Identifying palladium culprits in amine catalysis ', Nature Catalysis, vol. 4, pp. 994-998 . https://doi.org/10.1038/s41929-021-00710-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad7bbb1e33f693b8025eb92891cf89b
https://research-information.bris.ac.uk/en/publications/64d4489a-f26a-45b4-82ff-eab87036fd35
https://research-information.bris.ac.uk/en/publications/64d4489a-f26a-45b4-82ff-eab87036fd35
Autor:
Robin B. Bedford, Sanita B. Tailor
Publikováno v:
Tailor, S & Bedford, R B 2019, ' Can immobilization of an inactive iron species switch on catalytic activity in the Suzuki reaction? ', Catalysis Letters . https://doi.org/10.1007/s10562-019-02978-2
We examined the synthetic and catalytic claims that immobilization of an Fe-PNP pincer complex (1) on an amine-modified graphene oxide support yields a useful heterogeneous catalyst for the Suzuki biaryl cross-coupling reaction. Complex 1 is not form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e6415aa67bfbeed61323a2179b6127
https://doi.org/10.1007/s10562-019-02978-2
https://doi.org/10.1007/s10562-019-02978-2
Autor:
Mattia Manzotti, Soneela Asghar, Sanita B. Tailor, Benjamin J. S. Rowsell, Robin B. Bedford, Stephen L. J. Luckham, Hazel A. Sparkes
Publikováno v:
Tailor, S, Manzotti, M, Asghar, S, Rowsell, B, Luckham, S, Sparkes, H & Bedford, R 2019, ' Revisiting Claims of the Iron-, Cobalt-, Nickel-, and Copper-Catalyzed Suzuki Biaryl Cross-Coupling of Aryl Halides with Aryl Boronic Acids ', Organometallics, vol. 38, no. 8, pp. 1770-1777 . https://doi.org/10.1021/acs.organomet.9b00083
Intrigued by recent reports on the surprisingly excellent activity of a range of cobalt, iron, copper and nickelbased catalysts in the Suzuki biaryl cross-coupling of simple arylboronic acids with aryl halides, we undertook a reexamination of the syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac5d8e74af5f697c2748863f44e33fe
https://doi.org/10.1021/acs.organomet.9b00083
https://doi.org/10.1021/acs.organomet.9b00083
Autor:
Hazel A. Sparkes, Anna M. Winnicka, Andrew Horner, Carolina Méndez-Gálvez, David Elorriaga, Jack P.M. Roberts, Robin B. Bedford, Michelle Montgomery, Caitlin R. Bromfield, Harry M. O'Brien
Publikováno v:
Montgomery, M, O'Brien, H M, Méndez-Gálvez, C, Bromfield, C R, Roberts, J P M, Winnicka, A M, Horner, A, Elorriaga, D, Sparkes, H A & Bedford, R B 2019, ' The surprisingly facile formation of Pd(I)-phosphido complexes from ortho-biphenylphosphines and palladium acetate ', Dalton Transactions, vol. 48, no. 11, pp. 3539-3542 . https://doi.org/10.1039/c8dt04926b
The widely-used ortho-biphenylphosphine ligands SPhos and RuPhos not only undergo facile orthometallation with palladium acetate, yielding strained, four-membered dimeric palladacycles but more surprisingly, in the presence of alcoholic solvents, alo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0835a785ced1a436239b65b210475f29
https://doi.org/10.1039/c8dt04926b
https://doi.org/10.1039/c8dt04926b
Autor:
June Callison, Sean A. Davis, Harry M. O'Brien, Robin B. Bedford, Diego Gianolio, Stephen L. J. Luckham, David Elorriaga, Peter P. Wells, Hazel A. Sparkes, Antonis M. Messinis, Oscar Hernandez-Fajardo, Emma K. Gibson
Publikováno v:
Messinis, A M, Luckham, S L J, Wells, P P, Gianolio, D, Gibson, E K, O’Brien, H M, Sparkes, H A, Davis, S A, Callison, J, Elorriaga, D, Hernandez-Fajardo, O & Bedford, R B 2019, ' The highly surprising behaviour of diphosphine ligands in iron-catalysed Negishi cross-coupling ', Nature Catalysis, vol. 2, no. 2, pp. 123-133 . https://doi.org/10.1038/s41929-018-0197-z
Iron-catalysed cross-coupling is undergoing explosive development, but mechanistic understanding lags far behind synthetic methodology. Here, we find that the activity of iron–diphosphine pre-catalysts in the Negishi coupling of benzyl halides is s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50984acfc41253c3b869fbed99717e5f
https://doi.org/10.1038/s41929-018-0197-z
https://doi.org/10.1038/s41929-018-0197-z
Publikováno v:
Yu, S, Noble, A, Bedford, R B & Aggarwal, V K 2019, ' Methylenespiro[2.3]hexanes via Nickel-Catalyzed Cyclopropanations with [1.1.1]Propellane ', Journal of the American Chemical Society, vol. 141, no. 51, 51, pp. 20325-20334 . https://doi.org/10.1021/jacs.9b10689
Journal of the American Chemical Society
Journal of the American Chemical Society
[1.1.1]Propellane is a highly strained tricyclic hydrocarbon whose reactivity is dominated by addition reactions across the central inverted bond to provide bicyclo[1.1.1]pentane derivatives. These reactions proceed under both radical and two-electro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fad95668df94eb553d35c110277aa076
https://research-information.bris.ac.uk/en/publications/164218c5-4f74-4188-82bd-3ce48f8f94e2
https://research-information.bris.ac.uk/en/publications/164218c5-4f74-4188-82bd-3ce48f8f94e2
Autor:
Roman Abrams, Hazel A. Sparkes, Sean A. Davis, Mattia Manzotti, Harry M. O'Brien, David Elorriaga, Robin B. Bedford
Publikováno v:
O'Brien, H M, Manzotti, M, Abrams, R D, Elorriaga, D, Sparkes, H A, Davis, S A & Bedford, R B 2018, ' Iron-catalysed substrate-directed Suzuki biaryl cross-coupling ', Nature Catalysis, vol. 1, no. 6, pp. 429-437 . https://doi.org/10.1038/s41929-018-0081-x
Although the replacement of ubiquitous palladium catalysts with more sustainable iron-based analogues continues apace, the simple biaryl Suzuki cross-coupling reaction remains stubbornly elusive. It appears that the main issue hampering the reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b7d7f0ea3c9fd2cec9ef16d8157054
https://hdl.handle.net/1983/c20322e2-9b26-49a2-90c4-85b0652ca3c0
https://hdl.handle.net/1983/c20322e2-9b26-49a2-90c4-85b0652ca3c0
Publikováno v:
Asghar, S, Tailor, S B, Elorriaga, D & Bedford, R B 2017, ' Cobalt-Catalyzed Suzuki Biaryl Coupling of Aryl Halides ', Angewandte Chemie-International Edition, vol. 56, no. 51, pp. 16367-16370 . https://doi.org/10.1002/anie.201710053
Angewandte Chemie (International Ed. in English)
Angewandte Chemie (International Ed. in English)
Readily accessed cobalt pre-catalysts with N-heterocyclic carbene ligands catalyze the Suzuki cross-coupling of aryl chlorides and bromides with alkyllithium-activated arylboronic pinacolate esters. Preliminary mechanistic studies indicate that the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dcb9944ea16408417629710e40f51e6
https://hdl.handle.net/1983/55490513-d204-4d2c-9c37-ba655cd8b6a6
https://hdl.handle.net/1983/55490513-d204-4d2c-9c37-ba655cd8b6a6
Publikováno v:
Bedford, R B, Durrant, S J & Montgomery, M 2015, ' Catalyst-Switchable Regiocontrol in the Direct Arylation of Remote C—H Groups in Pyrazolo[1,5-a ]pyrimidines ', Angewandte Chemie-International Edition, vol. 54, no. 30, pp. 8787-8790 . https://doi.org/10.1002/anie.201502150
Angewandte Chemie (International Ed. in English)
Angewandte Chemie (International Ed. in English)
The regiodivergent palladium-catalyzed CH arylation of pyrazolo[1,5-a]pyrimidine has been achieved, wherein the switch in regioselectivity between positions C3 and C7 is under complete catalyst control. A phosphine-containing palladium catalyst promo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::157787eba05a323ce2d82224c03a5d33
https://doi.org/10.1002/anie.201502150
https://doi.org/10.1002/anie.201502150