High‐throughput CRISPRi phenotyping identifies new essential genes in Streptococcus pneumoniae

Autor: Xue Liu, Clement Gallay, Morten Kjos, Arnau Domenech, Jelle Slager, Sebastiaan P van Kessel, Kèvin Knoops, Robin A Sorg, Jing‐Ren Zhang, Jan‐Willem Veening

Publikováno v: Molecular Systems Biology, Vol 13, Iss 5, Pp 1-18 (2017)

Abstract Genome‐wide screens have discovered a large set of essential genes in the opportunistic human pathogen Streptococcus pneumoniae. However, the functions of many essential genes are still unknown, hampering vaccine development and drug disco

Externí odkaz: https://doaj.org/article/482825ddf1e3487fb3febf676c977939

Corrigendum to 'Functionality of a next generation biosynthetic bacterial 6-phytase in enhancing phosphorus availability to weaned piglets fed a corn-soybean meal-based diet without added inorganic phosphate' [Animal Nutrition 6/1 (2020) 24–30]

Autor: Yueming Dersjant-Li, Boris Villca, Vincent Sewalt, Arno de Kreij, Leon Marchal, Deepak E. Velayudhan, Robin A. Sorg, Trine Christensen, Rie Mejldal, Igor Nikolaev, Sina Pricelius, Hye-Sook Kim, Svend Haaning, Jens F. Sørensen, Rosil Lizardo

Publikováno v: Animal Nutrition, Vol 7, Iss 4, Pp 1388- (2021)

Externí odkaz: https://doaj.org/article/6776a06cfea241ae96ec65d4a00012e4

Switching off

Autor: Prasanna M. Bhogale, Robin A. Sorg, Jan-Willem Veening, Johannes Berg

Publikováno v: Biophysical Journal, 121(2), 183-192. CELL PRESS
Biophys J

The lactose uptake-pathway of E. coli is a paradigmatic example of multistability in gene-regulatory circuits. In the induced state of the lac-pathway, the genes comprising the lac-operon are transcribed, leading to the production of proteins which i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e33290e65d5b8115c4db6833676553d
https://hdl.handle.net/11370/58cc506c-3562-4a80-b1aa-953c14f23979

Synthetic gene-regulatory networks in the opportunistic human pathogen Streptococcus pneumoniae

Autor: Laurye Van Maele, Jean-Claude Sirard, Clement Gallay, Jan-Willem Veening, Robin A. Sorg

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 44, pp. 27608-27619
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2020, 117 (44), pp.27608-27619. ⟨10.1073/pnas.1920015117⟩
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (44), pp.27608-27619. ⟨10.1073/pnas.1920015117⟩
Proceedings of the National Academy of Sciences of the United States of America, 117(44):pnas.1920015117, 27608-27619. NATL ACAD SCIENCES

International audience; Streptococcus pneumoniae can cause disease in various human tissues and organs, including the ear, the brain, the blood, and the lung, and thus in highly diverse and dynamic environments. It is challenging to study how pneumoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f59ceea769f4a1f9fe0dd683ed28a9
https://serval.unil.ch/resource/serval:BIB_3E34132DBF98.P001/REF.pdf

Synthetic gene regulatory networks in the opportunistic human pathogen Streptococcus pneumoniae

Autor: Clement Gallay, Robin A. Sorg, Jan-Willem Veening

Streptococcus pneumoniaecan cause disease in various human tissues and organs, including the ear, the brain, the blood and the lung, and thus in highly diverse and dynamic environments. It is challenging to study how pneumococci control virulence fac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d20d71e6f5c710be661738446d4a3f4