Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Robin, Tranchant"'
Autor:
Lisa Quetel, Clément Meiller, Jean‐Baptiste Assié, Yuna Blum, Sandrine Imbeaud, François Montagne, Robin Tranchant, Julien deWolf, Stefano Caruso, Marie‐Christine Copin, Véronique Hofman, Laure Gibault, Cécile Badoual, Ecaterina Pintilie, Paul Hofman, Isabelle Monnet, Arnaud Scherpereel, Françoise Le Pimpec‐Barthes, Jessica Zucman‐Rossi, Marie‐Claude Jaurand, Didier Jean
Publikováno v:
Molecular Oncology, Vol 14, Iss 6, Pp 1207-1223 (2020)
Development of precision medicine for malignant pleural mesothelioma (MPM) requires a deep knowledge of tumor heterogeneity. Histologic and molecular classifications and histo‐molecular gradients have been proposed to describe heterogeneity, but a
Externí odkaz:
https://doaj.org/article/69f3c9f25b93468ea781ad245bb37fda
Autor:
Yuna Blum, Clément Meiller, Lisa Quetel, Nabila Elarouci, Mira Ayadi, Danisa Tashtanbaeva, Lucile Armenoult, François Montagne, Robin Tranchant, Annie Renier, Leanne de Koning, Marie-Christine Copin, Paul Hofman, Véronique Hofman, Henri Porte, Françoise Le Pimpec-Barthes, Jessica Zucman-Rossi, Marie-Claude Jaurand, Aurélien de Reyniès, Didier Jean
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Malignant pleural mesothelioma (MPM) is a rare and aggressive form of cancer. Here, the authors show MPM is heterogeneously composed of epithelioid and sarcomatoid components and their proportions associate with prognosis and could inform therapeutic
Externí odkaz:
https://doaj.org/article/0ac32d4c53d047abb1647a0e54445ec9
Autor:
Didier Jean, Marie-Claude Jaurand, Jessica Zucman-Rossi, Francoise Le Pimpec-Barthes, Aurelien de Reynies, Leanne de Koning, Annie Renier, Clement Meiller, Anne Tallet, Lisa Quetel, Robin Tranchant
This file contains supplementary tables S1- S5. Table S1: siRNA and TaqMan probes; Table S2: Primers used for LATS2 gene sequencing; Table S3: Differential phosphorylation level between C2LN MPM subgroup and other MPM; Table S4: LATS2 mutations in MP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3952df915601006b5f4269ccf4363b
https://doi.org/10.1158/1078-0432.22463601
https://doi.org/10.1158/1078-0432.22463601
Autor:
Francisco X. Real, Didier Jean, Walter Berger, Amancio Carnero, Simon T. Barry, Balazs Hegedus, Christine Pirker, Yuna Blum, Yves Allory, Clément Meiller, Jaime Martínez de Villarreal, Natalia del Pozo, Enrique Carrillo-de-Santa-Pau, Luis C. Fernández, María L. Suárez-Solís, Blanca Risa-Ebrí, Robin Tranchant, Miriam Marqués
Among malignant mesotheliomas (MM), the sarcomatoid subtype is associated with higher chemoresistance and worst survival. Due to its low incidence, there has been little progress in the knowledge of the molecular mechanisms associated with sarcomatoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5454e1ba1d65863defc6aec181824246
https://doi.org/10.1158/0008-5472.c.6512028
https://doi.org/10.1158/0008-5472.c.6512028
Autor:
Didier Jean, Marie-Claude Jaurand, Jessica Zucman-Rossi, Francoise Le Pimpec-Barthes, Aurelien de Reynies, Leanne de Koning, Annie Renier, Clement Meiller, Anne Tallet, Lisa Quetel, Robin Tranchant
This file contains the new supplementary Material and Methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dc6a7a0987f808c77e4d5849aa6374e
https://doi.org/10.1158/1078-0432.22463604
https://doi.org/10.1158/1078-0432.22463604
Autor:
Didier Jean, Marie-Claude Jaurand, Jessica Zucman-Rossi, Francoise Le Pimpec-Barthes, Aurelien de Reynies, Leanne de Koning, Annie Renier, Clement Meiller, Anne Tallet, Lisa Quetel, Robin Tranchant
This file contains the legends for supplementary Figures S1-S7.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ada91993eeb0898c7c5b49d655fa552
https://doi.org/10.1158/1078-0432.22463610.v1
https://doi.org/10.1158/1078-0432.22463610.v1
Autor:
Didier Jean, Marie-Claude Jaurand, Jessica Zucman-Rossi, Francoise Le Pimpec-Barthes, Aurelien de Reynies, Leanne de Koning, Annie Renier, Clement Meiller, Anne Tallet, Lisa Quetel, Robin Tranchant
This file contains supplementary Figures S1-S7. Figure S1: YAP1 and WWTR1 gene expression; Figure S2: LATS2 and NF2 siRNA knockdown efficiency; Figure S3: Effect of LATS2/NF2 co-inactivation on MPM cell proliferation, migration and invasion; Figure S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d19cc7080de44689db4938be624763ac
https://doi.org/10.1158/1078-0432.22463607.v1
https://doi.org/10.1158/1078-0432.22463607.v1
Autor:
Francisco X. Real, Didier Jean, Walter Berger, Amancio Carnero, Simon T. Barry, Balazs Hegedus, Christine Pirker, Yuna Blum, Yves Allory, Clément Meiller, Jaime Martínez de Villarreal, Natalia del Pozo, Enrique Carrillo-de-Santa-Pau, Luis C. Fernández, María L. Suárez-Solís, Blanca Risa-Ebrí, Robin Tranchant, Miriam Marqués
This file contains Supplementary Material and Methods. Supplementary Table S1 summarizes the antibodies used for IHC and WB; Supplementary Table S2 shows the primers and the shRNAs sequences used; Supplementary Table S3 shows the Selumetinib and AZD8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd3c1d8f9ba13598e06bdeb2f1c4fab
https://doi.org/10.1158/0008-5472.22425411
https://doi.org/10.1158/0008-5472.22425411
Autor:
Didier Jean, Marie-Claude Jaurand, Jessica Zucman-Rossi, Francoise Le Pimpec-Barthes, Aurelien de Reynies, Leanne de Koning, Annie Renier, Clement Meiller, Anne Tallet, Lisa Quetel, Robin Tranchant
Purpose: To better define malignant pleural mesothelioma (MPM) heterogeneity and identify molecular subtypes of MPM, we focus on the tumor suppressor gene LATS2, a member of the Hippo signaling pathway, which plays a key role in mesothelial carcinoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f3663a26b253261472a2e6db8be413
https://doi.org/10.1158/1078-0432.c.6525456.v1
https://doi.org/10.1158/1078-0432.c.6525456.v1
Autor:
Stefano Caruso, Yuna Blum, Lisa Quetel, Sandrine Imbeaud, Véronique Hofman, Arnaud Scherpereel, Laure Gibault, Ecaterina Pintilie, Françoise Le Pimpec-Barthes, Jessica Zucman-Rossi, Clément Meiller, François Montagne, Julien de Wolf, Didier Jean, Cécile Badoual, Paul Hofman, Jean-Baptiste Assié, Marie-Christine Copin, Isabelle Monnet, Marie-Claude Jaurand, Robin Tranchant
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 14, Iss 6, Pp 1207-1223 (2020)
Molecular Oncology, Vol 14, Iss 6, Pp 1207-1223 (2020)
Development of precision medicine for malignant pleural mesothelioma (MPM) requires a deep knowledge of tumor heterogeneity. Histologic and molecular classifications and histo‐molecular gradients have been proposed to describe heterogeneity, but a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abcd87b92bfdf2f6d6edeb61e7334dca
http://europepmc.org/articles/PMC7266286
http://europepmc.org/articles/PMC7266286