Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Robin, Gedschold"'
Autor:
Ghazl Al Hamwi, Vigneshwaran Namasivayam, Beatriz Büschbell, Robin Gedschold, Stefan Golz, Christa E. Müller
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract Patients with idiopathic pulmonary fibrosis show a strongly upregulated expression of chemokine CXCL14, whose target is still unknown. Screening of CXCL14 in a panel of human G protein-coupled receptors (GPCRs) revealed its potent and select
Externí odkaz:
https://doaj.org/article/70eb4b80053b4722bd6e602d10b141af
Autor:
Jan H. Voss, Haneen Al-Hroub, Robin Gedschold, Jennifer M. Dietrich, Evelyn Gaffal, Marieta Toma, Stefan Kehraus, Gabriele M. König, Peter Brust, Bernd K. Fleischmann, Daniela Wenzel, Winnie Deuther-Conrad, Christa E. Müller
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 57 (2022)
G protein-coupled receptors (GPCRs) transfer extracellular signals across cell membranes by activating intracellular heterotrimeric G proteins. Several studies suggested G proteins as novel drug targets for the treatment of complex diseases, e.g., as
Externí odkaz:
https://doaj.org/article/ab51b259cd79400aa01e768efdd94017
Autor:
Michał, Abram, Marcin, Jakubiec, Katelyn, Reeb, Mary Hongying, Cheng, Robin, Gedschold, Anna, Rapacz, Szczepan, Mogilski, Katarzyna, Socała, Dorota, Nieoczym, Małgorzata, Szafarz, Gniewomir, Latacz, Bartłomiej, Szulczyk, Justyna, Kalinowska-Tłuścik, Kinga, Gawel, Camila V, Esguerra, Elżbieta, Wyska, Christa E, Müller, Ivet, Bahar, Andréia C K, Fontana, Piotr, Wlaź, Rafał M, Kamiński, Krzysztof, Kamiński
Publikováno v:
Journal of medicinal chemistry. 65(17)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::338b23feb213a2d3ed90a9b7811d67f3
https://pubmed.ncbi.nlm.nih.gov/35984707
https://pubmed.ncbi.nlm.nih.gov/35984707
Autor:
Nina Geiger, Dominik Thimm, Thanigaimalai Pillaiyar, Robin Gedschold, Laura Schäkel, Michael Gütschow, Christa E. Müller, Ghazl Al Hamwi, Maria Zyulina, Vittoria Lopez, Christin Vielmuth, Katharina Sylvester, Miriam Diett, Lan Phuong Vu, Vigneshwaran Namasivayam, Julian Breidenbach, Anke C. Schiedel, Jochen Bodem, Salahuddin Mirza, Carina Lemke
Publikováno v:
Angewandte Chemie. 133:10515-10521
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ff9821b9fd888dcc360c6ff44e464c3
https://doi.org/10.1002/ange.202016961
https://doi.org/10.1002/ange.202016961
Autor:
Michał Abram, Marcin Jakubiec, Katelyn Reeb, Mary Hongying Cheng, Robin Gedschold, Anna Rapacz, Szczepan Mogilski, Katarzyna Socała, Dorota Nieoczym, Małgorzata Szafarz, Gniewomir Latacz, Bartłomiej Szulczyk, Justyna Kalinowska-Tłuścik, Kinga Gawel, Camila V. Esguerra, Elżbieta Wyska, Christa E. Müller, Ivet Bahar, Andréia C. K. Fontana, Piotr Wlaź, Rafał M. Kamiński, Krzysztof Kamiński
(R)-7 [(R)-AS-1] showed broad-spectrum antiseizure activity across in vivo mouse seizure models: maximal electroshock (MES), 6 Hz (32/44 mA), acute pentylenetetrazol (PTZ), and PTZ-kindling. A remarkable separation between antiseizure activity and CN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa9edda0a63b9b4c266dac589ff4f8da
https://ruj.uj.edu.pl/xmlui/handle/item/299969
https://ruj.uj.edu.pl/xmlui/handle/item/299969
Autor:
Salahuddin Mirza, Carina Lemke, Robin Gedschold, Dominik Thimm, Miriam Diett, Nina Geiger, Christa E. Müller, Julian Breidenbach, Michael Gütschow, Jochen Bodem, Christin Vielmuth, Anke C. Schiedel, Katharina Sylvester, Vittoria Lopez, Lan Phuong Vu, Vigneshwaran Namasivayam, Thanigaimalai Pillaiyar, Laura Schäkel, Ghazl Al Hamwi, Maria Zyulina
Publikováno v:
Angewandte Chemie (International Ed. in English)
The main protease of SARS‐CoV‐2 (Mpro), the causative agent of COVID‐19, constitutes a significant drug target. A new fluorogenic substrate was kinetically compared to an internally quenched fluorescent peptide and shown to be ideally suitable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad0987f44a1481deac8275f2d5abd33
http://europepmc.org/articles/PMC8014119
http://europepmc.org/articles/PMC8014119
Autor:
Dominik Thimm, Sonja Hinz, Christa E. Müller, Azeem Danish, Anke C. Schiedel, Christian Steinhäuser, Robin Gedschold, Peter Bedner
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1417, p 1417 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 3
International Journal of Molecular Sciences
Volume 22
Issue 3
Connexin gap junctions (Cx GJs) enable the passage of small molecules and ions between cells and are therefore important for cell-to-cell communication. Their dysfunction is associated with diseases, and small molecules acting as modulators of GJs ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa81101702b004b1e374195ee85ae9b1
https://doi.org/10.3390/ijms22031417
https://doi.org/10.3390/ijms22031417