Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Robia G Pautler"'
Autor:
Bibiana K Y Wong, Jaclyn B Murry, Rajesh Ramakrishnan, Fang He, Alfred Balasa, Gary R Stinnett, Steen E Pedersen, Robia G Pautler, Ignatia B Van den Veyver
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224876 (2019)
Gene-environment interactions contribute to the risk for Autism Spectrum Disorder (ASD). Among environmental factors, prenatal exposure to stress may increase the risk for ASD. To examine if there is an interaction between exposure to maternal stress
Externí odkaz:
https://doaj.org/article/c9f844e4a110406e8057fcb7eafb711d
Autor:
Ruchi Sharma, Eric Buras, Tomoya Terashima, Faridis Serrano, Cynthia A Massaad, Lingyun Hu, Brittany Bitner, Taeko Inoue, Lawrence Chan, Robia G Pautler
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13463 (2010)
While hyperglycemia-induced oxidative stress damages peripheral neurons, technical limitations have, in part, prevented in vivo studies to determine the effect of hyperglycemia on the neurons in the central nervous system (CNS). While olfactory dysfu
Externí odkaz:
https://doaj.org/article/bdc7f8a70bb840c4a5c2da6275629497
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10561 (2010)
Alzheimer's disease (AD) is a neurodegenerative disease characterized by the progressive decline in cognitive functions and the deposition of aggregated amyloid beta (Abeta) into senile plaques and the protein tau into tangles. In addition, a general
Externí odkaz:
https://doaj.org/article/e9936071a62947e9be9a4b3211e38549
Autor:
Donna M. Peehl, Cristian T. Badea, Thomas L. Chenevert, Heike E. Daldrup-Link, Li Ding, Lacey E. Dobrolecki, A. McGarry Houghton, Paul E. Kinahan, John Kurhanewicz, Michael T. Lewis, Shunqiang Li, Gary D. Luker, Cynthia X. Ma, H. Charles Manning, Yvonne M. Mowery, Peter J. O'Dwyer, Robia G. Pautler, Mark A. Rosen, Raheleh Roudi, Brian D. Ross, Kooresh I. Shoghi, Renuka Sriram, Moshe Talpaz, Richard L. Wahl, Rong Zhou
Publikováno v:
Tomography, Vol 9, Iss 2, Pp 657-680 (2023)
The availability of high-fidelity animal models for oncology research has grown enormously in recent years, enabling preclinical studies relevant to prevention, diagnosis, and treatment of cancer to be undertaken. This has led to increased opportunit
Externí odkaz:
https://doaj.org/article/315dd791b13b4c40966ef7abc8d61d4c
Autor:
Dariya Malyarenko, Ghoncheh Amouzandeh, Stephen Pickup, Rong Zhou, Henry Charles Manning, Seth T. Gammon, Kooresh I. Shoghi, James D. Quirk, Renuka Sriram, Peder Larson, Michael T. Lewis, Robia G. Pautler, Paul E. Kinahan, Mark Muzi, Thomas L. Chenevert
Publikováno v:
Tomography, Vol 9, Iss 1, Pp 375-386 (2023)
Relevant to co-clinical trials, the goal of this work was to assess repeatability, reproducibility, and bias of the apparent diffusion coefficient (ADC) for preclinical MRIs using standardized procedures for comparison to performance of clinical MRIs
Externí odkaz:
https://doaj.org/article/9222f4abb7d4458ca75182c703cf97ac
Autor:
Jordan Kho, Urszula Polak, Ming-Ming Jiang, John D. Odom, Jill V. Hunter, Saima M. Ali, Lindsay C. Burrage, Sandesh C.S. Nagamani, Robia G. Pautler, Hannah P. Thompson, Akihiko Urayama, Zixue Jin, Brendan Lee
Publikováno v:
JCI Insight, Vol 8, Iss 17 (2023)
Nitric oxide (NO) is a critical signaling molecule that has been implicated in the pathogenesis of neurocognitive diseases. Both excessive and insufficient NO production have been linked to pathology. Previously, we have shown that argininosuccinate
Externí odkaz:
https://doaj.org/article/6775588bb4dc4e2abf6ec0fb79c6a418
Autor:
Lindsay C. Fadel, Ivany V. Patel, Jonathan Romero, I-Chih Tan, Shelli R. Kesler, Vikram Rao, S. A. Amali S. Subasinghe, Russell S. Ray, Jason T. Yustein, Matthew J. Allen, Brian W. Gibson, Justin J. Verlinden, Stanley Fayn, Nicole Ruggiero, Caitlyn Ortiz, Elizabeth Hipskind, Aaron Feng, Chijindu Iheanacho, Alex Wang, Robia G. Pautler
Publikováno v:
Biosensors, Vol 12, Iss 8, p 616 (2022)
Anesthesia is often used in preclinical imaging studies that incorporate mouse or rat models. However, multiple reports indicate that anesthesia has significant physiological impacts. Thus, there has been great interest in performing imaging studies
Externí odkaz:
https://doaj.org/article/e3590e0019ec447e8aabbbe88387c59e
Autor:
S. A. Amali S. Subasinghe, Caitlyn J. Ortiz, Jonathan Romero, Cassandra L. Ward, Alexander G. Sertage, Lyazat Kurenbekova, Jason T. Yustein, Robia G. Pautler, Matthew J. Allen
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Hypoxia is a prognostic biomarker of rapidly growing cancers, where the extent of hypoxia is an indication of tumor progression and prognosis; therefore, hypoxia is also used for staging while performing chemo- and radiotherapeutics for cancer. Contr
Autor:
Md Mamunur Rashid, Brooke A. Corbin, Pavan Jella, Caitlyn J. Ortiz, Md. Abul Hassan Samee, Robia G. Pautler, Matthew J. Allen
Publikováno v:
Journal of the American Chemical Society. 144(50)
Hypoxia is a hallmark of many diseases, including cancer, arthritis, heart and kidney diseases, and diabetes, and it is often associated with disease aggressiveness and poor prognosis. Consequently, there is a critical need for imaging hypoxia in a n
Autor:
Jonathan Romero, Nino Rainusso, Cory V Noel, Matthew J. Robertson, Robia G. Pautler, Cristian Coarfa, Prakash Masand
Publikováno v:
Cardio-Oncology, Vol 7, Iss 1, Pp 1-10 (2021)
Cardio-oncology
Cardio-oncology
Background Cancer therapy-related cardiac dysfunction may occur in pediatric cancer survivors. Identification of early markers of myocardial damage secondary to anthracycline exposure is crucial to develop strategies that may ameliorate this complica