Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Robi D Mitra"'
Autor:
Michael D Brooks, Erin Jackson, Nicole M Warrington, Jingqin Luo, Jason T Forys, Sara Taylor, Diane D Mao, Jeffrey R Leonard, Albert H Kim, David Piwnica-Worms, Robi D Mitra, Joshua B Rubin
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107397 (2014)
Cell-cell interactions between tumor cells and constituents of their microenvironment are critical determinants of tumor tissue biology and therapeutic responses. Interactions between glioblastoma (GBM) cells and endothelial cells (ECs) establish a p
Externí odkaz:
https://doaj.org/article/4bc889b331cf44b09ca81cd65b5195be
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67801 (2013)
In order to facilitate understanding of pigment cell biology, we developed a method to concomitantly purify melanocytes, iridophores, and retinal pigmented epithelium from zebrafish, and analyzed their transcriptomes. Comparing expression data from t
Externí odkaz:
https://doaj.org/article/25092cce79294fc9ad2b770ab927afe7
Autor:
Carlos Cruchaga, Gabe Haller, Sumitra Chakraverty, Kevin Mayo, Francesco L M Vallania, Robi D Mitra, Kelley Faber, Jennifer Williamson, Tom Bird, Ramon Diaz-Arrastia, Tatiana M Foroud, Bradley F Boeve, Neill R Graff-Radford, Pamela St Jean, Michael Lawson, Margaret G Ehm, Richard Mayeux, Alison M Goate, NIA-LOAD/NCRAD Family Study Consortium
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31039 (2012)
Pathogenic mutations in APP, PSEN1, PSEN2, MAPT and GRN have previously been linked to familial early onset forms of dementia. Mutation screening in these genes has been performed in either very small series or in single families with late onset AD (
Externí odkaz:
https://doaj.org/article/00e347ba0885474d87ad4841483412db
Autor:
Eleanor I. Sams, Jeffrey K. Ng, Victoria Tate, Ying-Chen Claire Hou, Yang Cao, Lucinda Antonacci-Fulton, Khadija Belhassan, Julie Neidich, Robi D. Mitra, F. Sessions Cole, Patricia Dickson, Jeffrey Milbrandt, Tychele N. Turner
Publikováno v:
HGG Advances, Vol 3, Iss 1, Pp 100081- (2022)
While 9p deletion and duplication syndromes have been studied for several years, small sample sizes and minimal high-resolution data have limited a comprehensive delineation of genotypic and phenotypic characteristics. In this study, we examined gene
Externí odkaz:
https://doaj.org/article/430a1f3c59fe42e7b91d28106053d35a
Publikováno v:
BMC Medical Genomics, Vol 11, Iss 1, Pp 1-11 (2018)
Abstract Background BAP1 is a histone deubiquitinase that acts as a tumor and metastasis suppressor associated with disease progression in human cancer. We have used the “Calling Card System” of transposase-directed transposon insertion mapping t
Externí odkaz:
https://doaj.org/article/f6617867d8cc443281fd781412d4123e
Publikováno v:
ACS Synthetic Biology. 12:624-633
Autor:
Pamela S Recio, Nikhil J Mitra, Christian A Shively, David Song, Grace Jaramillo, Kristine Shady Lewis, Xuhua Chen, Robi D Mitra
Publikováno v:
Nucleic Acids Research.
Gene expression changes are orchestrated by transcription factors (TFs), which bind to DNA to regulate gene expression. It remains surprisingly difficult to predict basic features of the transcriptional process, including in vivo TF occupancy. Existi
Autor:
Alex L. Yenkin, John C. Bramley, Colin L. Kremitzki, Jason E. Waligorski, Mariel J. Liebeskind, Xinyuan E. Xu, Vinay D. Chandrasekaran, Maria A. Vakaki, Graham W. Bachman, Robi D. Mitra, Jeffrey D. Milbrandt, William J. Buchser
Publikováno v:
Communications Biology. 5
Most human genetic variation is classified as variants of uncertain significance. While advances in genome editing have allowed innovation in pooled screening platforms, many screens deal with relatively simple readouts (viability, fluorescence) and
Autor:
Matthew Lalli, Allen Yen, Urvashi Thopte, Fengping Dong, Arnav Moudgil, Xuhua Chen, Jeffrey Milbrandt, Joseph D. Dougherty, Robi D. Mitra
Publikováno v:
NAR genomics and bioinformatics. 4(3)
Calling cards technology using self-reporting transposons enables the identification of DNA-protein interactions through RNA sequencing. Although immensely powerful, current implementations of calling cards in bulk experiments on populations of cells
Autor:
Richard D. Head, Matthew A. Lalli, Robert S. Fulton, Jeffrey Milbrandt, Michael N. Wilkinson, Catrina Fronick, Christopher S. Sawyer, Robi D. Mitra, Michael E. Heinz, Joshua S Langmade, Xuhua Chen, Lauren C. Burcea, William Buchser
Publikováno v:
Clinical Chemistry
Background Rapid, reliable, and widespread testing is required to curtail the ongoing COVID-19 pandemic. Current gold-standard nucleic acid tests are hampered by supply shortages in critical reagents including nasal swabs, RNA extraction kits, person