Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Robi D Mitra"'
Autor:
Alex L. Yenkin, John C. Bramley, Colin L. Kremitzki, Jason E. Waligorski, Mariel J. Liebeskind, Xinyuan E. Xu, Vinay D. Chandrasekaran, Maria A. Vakaki, Graham W. Bachman, Robi D. Mitra, Jeffrey D. Milbrandt, William J. Buchser
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Raft-Seq is a generalizable pooled screening platform that combines high-content imaging, machine learning and microraft isolation, and enables efficient screening of genetic perturbations based on their impact on phenotypes.
Externí odkaz:
https://doaj.org/article/63108157402f4421b5e89ea34d7f7eab
Autor:
Eleanor I. Sams, Jeffrey K. Ng, Victoria Tate, Ying-Chen Claire Hou, Yang Cao, Lucinda Antonacci-Fulton, Khadija Belhassan, Julie Neidich, Robi D. Mitra, F. Sessions Cole, Patricia Dickson, Jeffrey Milbrandt, Tychele N. Turner
Publikováno v:
HGG Advances, Vol 3, Iss 1, Pp 100081- (2022)
While 9p deletion and duplication syndromes have been studied for several years, small sample sizes and minimal high-resolution data have limited a comprehensive delineation of genotypic and phenotypic characteristics. In this study, we examined gene
Externí odkaz:
https://doaj.org/article/430a1f3c59fe42e7b91d28106053d35a
Publikováno v:
ACS Synthetic Biology. 12:624-633
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e047fa016b87d7b6c235888aaba509a
https://doi.org/10.1021/acssynbio.2c00547
https://doi.org/10.1021/acssynbio.2c00547
Publikováno v:
BMC Medical Genomics, Vol 11, Iss 1, Pp 1-11 (2018)
Abstract Background BAP1 is a histone deubiquitinase that acts as a tumor and metastasis suppressor associated with disease progression in human cancer. We have used the “Calling Card System” of transposase-directed transposon insertion mapping t
Externí odkaz:
https://doaj.org/article/f6617867d8cc443281fd781412d4123e
Autor:
Pamela S Recio, Nikhil J Mitra, Christian A Shively, David Song, Grace Jaramillo, Kristine Shady Lewis, Xuhua Chen, Robi D Mitra
Publikováno v:
Nucleic Acids Research.
Gene expression changes are orchestrated by transcription factors (TFs), which bind to DNA to regulate gene expression. It remains surprisingly difficult to predict basic features of the transcriptional process, including in vivo TF occupancy. Existi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4245f14e60e75bf435001734fa1f8302
https://doi.org/10.1093/nar/gkad320
https://doi.org/10.1093/nar/gkad320
Autor:
Denis Avey, Sumithra Sankararaman, Aldrin K.Y. Yim, Ruteja Barve, Jeffrey Milbrandt, Robi D. Mitra
Publikováno v:
Cell Reports, Vol 24, Iss 13, Pp 3619-3629.e4 (2018)
Summary: Molecular and behavioral responses to opioids are thought to be primarily mediated by neurons, although there is accumulating evidence that other cell types play a prominent role in drug addiction. To investigate cell-type-specific opioid re
Externí odkaz:
https://doaj.org/article/e6f4ec3650f64052bf6a9e934b123d3f
Autor:
Matthew Lalli, Allen Yen, Urvashi Thopte, Fengping Dong, Arnav Moudgil, Xuhua Chen, Jeffrey Milbrandt, Joseph D. Dougherty, Robi D. Mitra
Publikováno v:
NAR genomics and bioinformatics. 4(3)
Calling cards technology using self-reporting transposons enables the identification of DNA-protein interactions through RNA sequencing. Although immensely powerful, current implementations of calling cards in bulk experiments on populations of cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb149f4184708165ae5a1c762d42a07c
https://pubmed.ncbi.nlm.nih.gov/36062164
https://pubmed.ncbi.nlm.nih.gov/36062164
Autor:
Richard D. Head, Matthew A. Lalli, Robert S. Fulton, Jeffrey Milbrandt, Michael N. Wilkinson, Catrina Fronick, Christopher S. Sawyer, Robi D. Mitra, Michael E. Heinz, Joshua S Langmade, Xuhua Chen, Lauren C. Burcea, William Buchser
Publikováno v:
Clinical Chemistry
Background Rapid, reliable, and widespread testing is required to curtail the ongoing COVID-19 pandemic. Current gold-standard nucleic acid tests are hampered by supply shortages in critical reagents including nasal swabs, RNA extraction kits, person
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db7f6b2e36a5515c478843ea44e03a6
https://doi.org/10.1093/clinchem/hvaa267
https://doi.org/10.1093/clinchem/hvaa267
Autor:
Robi D. Mitra, Katherine B. McCullough, Susan E. Maloney, June He, Allen Yen, Mark Shabsovich, Joseph D. Dougherty, Michael J. Vasek, Arnav Moudgil, Jiayang Chen, Tomas Lagunas, Timothy M. Miller, Alexander J. Cammack, Michael N. Wilkinson, Misha Hooda, Xuhua Chen
Publikováno v:
Proc Natl Acad Sci U S A
Transcription factors (TFs) enact precise regulation of gene expression through site-specific, genome-wide binding. Common methods for TF-occupancy profiling, such as chromatin immunoprecipitation, are limited by requirement of TF-specific antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d42bde89ba22c5e1c3db12776c8faa8
https://doi.org/10.1073/pnas.1918241117
https://doi.org/10.1073/pnas.1918241117
Autor:
Aldrin K. Y. Yim, Peter L. Wang, John R. Bermingham, Amber Hackett, Amy Strickland, Timothy M. Miller, Cindy Ly, Robi D. Mitra, Jeffrey Milbrandt
Publikováno v:
Nat Neurosci
The peripheral nerve contains diverse cell types that support its proper function and maintenance. We analyzed multiple peripheral nerves using single-nuclei RNA-sequencing (snRNA-seq), which allowed us to circumvent difficulties encountered in analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad9132374a8d3b7e16cb4dc0d0f9e53
https://europepmc.org/articles/PMC9060899/
https://europepmc.org/articles/PMC9060899/
