Rapid and sustained B-cell depletion with subcutaneous ofatumumab in relapsing multiple sclerosis: APLIOS, a randomized phase-2 study

Autor: Bar-Or, Amit, Wiendl, Heinz, Montalban, Xavier, Alvarez, Enrique, Davydovskaya, Maria, Delgado, Silvia R., Evdoshenko, Evgeniy P., Giedraitiene, Natasa, Gross-Paju, Katrin, Haldre, Sulev, Herrman, Craig E., Izquierdo, Guillermo, Karelis, Guntis, Leutmezer, Fritz, Mares, Miroslav, Meca-Lallana, Jose Eustasio, Mickeviciene, Dalia, Nicholas, Jacqueline, Robertson, Derrick S., Sazonov, Denis V., Sharlin, Kenneth, Sundaram, Bharathy, Totolyan, Natalia, Vachova, Marta, Valis, Martin, Bagger, Morten, Häring, Dieter A., Ludwig, Inga, Willi, Roman, Zalesak, Martin, Su, Wendy, Merschhemke, Martin, Fox, Edward J., Universitat Autònoma de Barcelona

Publikováno v: Multiple sclerosis, London : Sage Publications Ltd., 2022, vol. 28, no. 6, p. 910-924
Scientia

Ofatumumab; Multiple sclerosis; Pharmacokinetics Ofatumumab; Esclerosis múltiple; Farmacocinética Ofatumumab; Esclerosi múltiple; Farmacocinètica Background: Ofatumumab, the first fully human anti-CD20 monoclonal antibody, is approved in several

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea82473f15eae98cbca7008483f7bdd
https://pubmed.ncbi.nlm.nih.gov/34605319

(DMT26) Longer-Term Safety and Efficacy of Ofatumumab in People With Relapsing Multiple Sclerosis Up to 6 Years.

Autor: Wiendl, Heinz, Hauser, Stephen L., Nicholas, Jacqueline A., de Sèze, Jérôme, Meuth, Sven G., Giacomini, Paul S., Robertson, Derrick S., Wray, Sibyl, Bhatt, Alit, Xixi Hu, Haoyi Fu, Jehl, Valentine, Sullivan, Roseanne, Boer, Ibolya, Cohen, Jeffrey A., Kappos, Ludwig

Publikováno v: International Journal of MS Care; 2024 Supplement, Vol. 26, p35-36, 2p

Rapid and sustained B-cell depletion with subcutaneous ofatumumab in relapsing multiple sclerosis: APLIOS, a randomized phase-2 study.

Autor: Bar-Or, Amit, Wiendl, Heinz, Montalban, Xavier, Alvarez, Enrique, Davydovskaya, Maria, Delgado, Silvia R, Evdoshenko, Evgeniy P, Giedraitiene, Natasa, Gross-Paju, Katrin, Haldre, Sulev, Herrman, Craig E, Izquierdo, Guillermo, Karelis, Guntis, Leutmezer, Fritz, Mares, Miroslav, Meca-Lallana, Jose E, Mickeviciene, Dalia, Nicholas, Jacqueline, Robertson, Derrick S, Sazonov, Denis V

Publikováno v: Multiple Sclerosis Journal; May2022, Vol. 28 Issue 6, p910-924, 15p

(DMT27) A Single-Center Prospective Measurement of Upper Extremity Function in Patients With Multiple Sclerosis With Advanced Disability Treated With Ocrevus.

Autor: Maldonado, Janice, Robertson, Derrick S., Brugal, Luis Compres, Aungst, Angela, Schneider, Raymond, McPherson, Amber, Brown, Janaye L., Gummalla, Sucharita

Publikováno v: International Journal of MS Care; 2024 Supplement, Vol. 26, p36-36, 1/3p

Rapid and sustained B-cell depletion with subcutaneous ofatumumab in relapsing multiple sclerosis: APLIOS, a randomized phase-2 study.

Autor: Bar-Or A; A Bar-Or Center for Neuroinflammation and Experimental Therapeutics and Department of Neurology, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street - 3 Gates Building, Philadelphia, PA 19104, USA.; Center for Neuroinflammation and Experimental Therapeutics and Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Wiendl H; Department of Neurology with Institute of Translational Neurology, University of Münster, Münster, Germany., Montalban X; Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Hospital Universitari Vall d'Hebron, Barcelona, Spain., Alvarez E; Department of Neurology, Rocky Mountain MS Center, University of Colorado, Aurora, CO, USA., Davydovskaya M; Pirogov Russian National Research Medical University, Moscow, Russian Federation., Delgado SR; MS Center and Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL, USA., Evdoshenko EP; St Petersburg Center for Multiple Sclerosis and Other Autoimmune Diseases, St Petersburg, Russian Federation., Giedraitiene N; Clinic of Neurology and Neurosurgery, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania., Gross-Paju K; West-Tallinn Central Hospital, Tallinn, Estonia/Institute of Health Care Technology, TalTech, Tallinn, Estonia., Haldre S; Department of Neurology and Neurosurgery, University of Tartu, Tartu, Estonia/Neurology Clinic, Tartu University Hospital, Tartu, Estonia., Herrman CE; JWM Neurology, Indianapolis, IN, USA., Izquierdo G; Multiple Sclerosis Unit, Hospital Vithas NISA Sevilla, Sevilla, Spain., Karelis G; Neurology and Neurosurgery Department, Riga East University Hospital and Riga Stradins University, Riga, Latvia., Leutmezer F; Department of Neurology, Medical University of Vienna, Vienna, Austria., Mares M; Department of Neurology, Pardubice Regional Hospital, Pardubice, Czech Republic., Meca-Lallana JE; Multiple Sclerosis CSUR, Department of Neurology, Virgen de la Arrixaca Clinical University Hospital-IMIB-Arrixaca, Murcia, Spain/Clinical Neuroimmunology and Multiple Sclerosis Cathedra, Universidad Católica San Antonio (UCAM), Murcia, Spain., Mickeviciene D; Lithuanian University of Health Sciences, Kaunas, Lithuania., Nicholas J; OhioHealth Riverside Methodist Hospital, Columbus, OH, USA., Robertson DS; Multiple Sclerosis Division, Department of Neurology, Morsani College of Medicine, University of South Florida, Tampa, FL, USA., Sazonov DV; Department of Clinical Trials FSBIH SDMC of FMBA of Russia, Novosibirsk, Russian Federation., Sharlin K; Sharlin Health and Neurology, Ozark, MO, USA., Sundaram B; Texas Institute for Neurological Disorders, Sherman, TX, USA., Totolyan N; Department of Neurology, First Pavlov State Medical University of St Petersburg, St Petersburg, Russian Federation., Vachova M; Department of Neurology, Teplice Hospital, Teplice, Czech Republic., Valis M; Department of Neurology, Faculty of Medicine in Hradec Králové, Charles University in Prague and University Hospital Hradec Králové, Hradec Králové, Czech Republic., Bagger M; Novartis Pharma AG, Basel, Switzerland., Häring DA; Novartis Pharma AG, Basel, Switzerland., Ludwig I; Novartis Pharma AG, Basel, Switzerland., Willi R; Novartis Pharma AG, Basel, Switzerland., Zalesak M; Novartis Pharma AG, Basel, Switzerland., Su W; Novartis Pharmaceutical Corporation, East Hanover, NJ, USA., Merschhemke M; Novartis Pharma AG, Basel, Switzerland., Fox EJ; Central Texas Neurology Consultants PA, Round Rock, TX, USA.

Publikováno v: Multiple sclerosis (Houndmills, Basingstoke, England) [Mult Scler] 2022 May; Vol. 28 (6), pp. 910-924. Date of Electronic Publication: 2021 Oct 04.