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The discovery of IsoPs has been an interesting development for a number of reasons, apart from the fact that it involves novel biochemistry. The simple fact that prostanoids are produced nonenzymatically in prodigous quantities in vivo and in much gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af7383574d562c0bb478687f3c8800f2
https://doi.org/10.1385/1-59259-263-5:257
https://doi.org/10.1385/1-59259-263-5:257
Autor:
Roberts Lj nd, Jason D. Morrow
This chapter has outlined methods to assess lipid peroxidation associated with oxidant injury in vivo by quantifying concentrations of free F2-IsoPs in biological fluids and levels of F2-IsoPs esterified in tissue lipids. The mass spectrometric assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a89ebaf7915427c7a991ee31edf4087a
https://doi.org/10.1016/s0076-6879(99)00106-8
https://doi.org/10.1016/s0076-6879(99)00106-8
Autor:
Roberts Lj nd, Jason D. Morrow
Publikováno v:
Annals of the New York Academy of Sciences. 744
It was recently discovered that a series of structurally unique prostaglandin F2-like compounds (F2-isoprostanes) capable of exerting potent biological activity are produced in vivo in humans by a noncyclooxygenase mechanism involving free radical ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbfff7f78da52e67bf10f029dcf0d68a
https://pubmed.ncbi.nlm.nih.gov/7825845
https://pubmed.ncbi.nlm.nih.gov/7825845
Publisher Summary Quantification of endogenous thromboxane A 2 (TxA 2 ) production in man may provide a reliable index of platelet activation in vivo and have considerable relevance to understanding the role of platelets in these conditions. The quan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::930e2485945005fcfcfb9c6aedf08a77
https://doi.org/10.1016/0076-6879(82)86230-7
https://doi.org/10.1016/0076-6879(82)86230-7