Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Roberto de la Salud-Bea"'
Publikováno v:
Antibiotics, Vol 10, Iss 10, p 1208 (2021)
The antibiotic and toxic properties for four synthetic analogs of eumenine mastoparan peptides (EMP) have been tested. These properties were compared to two natural peptides found in the venom of solitary wasps Anterhynchium flavomarginatum micado (n
Externí odkaz:
https://doaj.org/article/4e6aafc4118c4372bf7f387b31633c63
Autor:
Roberto de la Salud Bea, Elaine Frawley, Qian Shen, Sydney Moyo, Jeremy M. Thelven, Lily North
Publikováno v:
Toxicon. 224:107032
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::582e1278c29eab4f63e3fe15e15dc6f5
https://doi.org/10.1016/j.toxicon.2023.107032
https://doi.org/10.1016/j.toxicon.2023.107032
Publikováno v:
Antibiotics
Volume 10
Issue 10
Antibiotics, Vol 10, Iss 1208, p 1208 (2021)
Volume 10
Issue 10
Antibiotics, Vol 10, Iss 1208, p 1208 (2021)
The antibiotic and toxic properties for four synthetic analogs of eumenine mastoparan peptides (EMP) have been tested. These properties were compared to two natural peptides found in the venom of solitary wasps Anterhynchium flavomarginatum micado (n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774a54e664a51ddd673d914302ef6d52
https://pubmed.ncbi.nlm.nih.gov/34680789
https://pubmed.ncbi.nlm.nih.gov/34680789
Autor:
David B. Berkowitz, Jill Marie Sturdivant, Matthew L. Beio, Christopher D. McCune, Roberto de la Salud-Bea, Brendan M. Darnell
Publikováno v:
Journal of the American Chemical Society. 139:14077-14089
Developing specific chemical functionalities to deploy in biological environments for targeted enzyme inactivation lies at the heart of mechanism-based inhibitor (MBI) development, but also is central to other protein-tagging methods in modern chemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f1a9cc84b61cf920367f828051b6f3d
https://doi.org/10.1021/jacs.7b04690
https://doi.org/10.1021/jacs.7b04690
Publikováno v:
Antibiotics; Volume 6; Issue 3; Pages: 13
Antibiotics
Antibiotics
Seven analogs of the natural, α-helix peptides IsCT1 and IsCT2—found in the venom of scorpion Opithancatus Madagascariensis—have been synthesized and tested to compare their antibacterial and hemolytic activity against natural peptides. In gener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e871ee424f404d25e54af5b90c8a646e
Publikováno v:
Biochemistry. 48:10810-10817
The incorporation of extensively fluorinated, or fluorous, analogues of hydrophobic amino acids into proteins potentially provides the opportunity to modulate the physicochemical properties of proteins in a predictable manner. On the basis of the pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d5caf09c5ac86fc46f6fb1a540255b2
https://doi.org/10.1021/bi901481k
https://doi.org/10.1021/bi901481k
Publikováno v:
Peptides. 68
Five analogs of a natural peptide (BmKn1) found in the venom of scorpion Buthus martensii Karsh have been synthesized and tested to compare their antimicrobial and hemolytic activity with the wild type. Circular dichroism spectra show that these pept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c434820d7c17f0ec84dbe578068bb0
https://pubmed.ncbi.nlm.nih.gov/25451872
https://pubmed.ncbi.nlm.nih.gov/25451872
Autor:
Ma̱ Luisa Testa, José Sepúlveda-Arques, Elena Zaballos-García, Chakib Hajji, Juan Server-Carrió, Roberto de la Salud-Bea
Publikováno v:
Scopus-Elsevier
Enantiomerically pure 4,5-disubstituted 3-methyltetrahydro-1,3-oxazines have been obtained by reaction of 3-methylamino-1,2-diols with dichloromethane by regioselective differentiation of hydroxyl groups.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::359e502d1cc2bcd7c71fbc1612d9b05c
https://doi.org/10.1016/s0040-4020(00)00744-4
https://doi.org/10.1016/s0040-4020(00)00744-4
Autor:
Jeffrey R. Brender, E. Neil G. Marsh, Ayyalusamy Ramamoorthy, Subramanian Vivekanandan, Ravi Prakash Reddy Nanga, Nataliya Popovych, Roberto de la Salud Bea, Kevin Hartman
Publikováno v:
Journal of the American Chemical Society. 132(26)
Human Islet Amyloid Polypeptide (hIAPP) is a highly amyloidogenic protein found in islet cells of patients with type II diabetes. Because hIAPP is highly toxic to beta-cells under certain conditions, it has been proposed that hIAPP is linked to the l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6f36dd2bb81e024db9343c5ba1c2e57
https://pubmed.ncbi.nlm.nih.gov/20536124
https://pubmed.ncbi.nlm.nih.gov/20536124
Autor:
Roberto de la Salud-Bea, Kannan R. Karukurichi, Gourhari Maiti, David B. Berkowitz, Jill M. McFadden, Michelle L. Morris
Publikováno v:
ChemInform. 41
This chapter provides an overview of a program directed at the synthesis of amino acids (AA's) bearing a vinyl substituent in place of the usual α-proton. These quaternary amino acids are of interest, in and of themselves, as mechanism-based inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6d4fdca9257c3bc4fdd3aafb65ed923
https://doi.org/10.1002/chin.201001234
https://doi.org/10.1002/chin.201001234