Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Roberto Vera Alvarez"'
Autor:
Roberto Vera Alvarez, David Landsman
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-21 (2024)
Abstract The cost and complexity of generating a complete reference genome means that many organisms lack an annotated reference. An alternative is to use a de novo reference transcriptome. This technology is cost-effective but is susceptible to off-
Externí odkaz:
https://doaj.org/article/2c915c63d4ab493b8cc65bce4cdf2ca6
Autor:
Manoj Kumar Kashyap, Hiren Karathia, Deepak Kumar, Roberto Vera Alvarez, Jose Vicente Forero-Forero, Eider Moreno, Juliana Velez Lujan, Carlos Ivan Amaya-Chanaga, Newton Medeiros Vidal, Zhe Yu, Emanuela M. Ghia, Paula A. Lengerke-Diaz, Daniel Achinko, Michael Y. Choi, Laura Z. Rassenti, Leonardo Mariño-Ramírez, Stephen M. Mount, Sridhar Hannenhalli, Thomas J. Kipps, Januario E. Castro
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 2, Pp 102202- (2024)
Splicing factor 3b subunit 1 (SF3B1) is the largest subunit and core component of the spliceosome. Inhibition of SF3B1 was associated with an increase in broad intron retention (IR) on most transcripts, suggesting that IR can be used as a marker of s
Externí odkaz:
https://doaj.org/article/adf59c81f6f94126a63b606708311ab5
Autor:
Christiam Camacho, Grzegorz M. Boratyn, Victor Joukov, Roberto Vera Alvarez, Thomas L. Madden
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-16 (2023)
Abstract Background Biomedical researchers use alignments produced by BLAST (Basic Local Alignment Search Tool) to categorize their query sequences. Producing such alignments is an essential bioinformatics task that is well suited for the cloud. The
Externí odkaz:
https://doaj.org/article/9c448c5eaf504321ba18f6ad325d161d
Autor:
Lorinc S. Pongor, Jacob M. Gross, Roberto Vera Alvarez, Junko Murai, Sang-Min Jang, Hongliang Zhang, Christophe Redon, Haiqing Fu, Shar-Yin Huang, Bhushan Thakur, Adrian Baris, Leonardo Marino-Ramirez, David Landsman, Mirit I. Aladjem, Yves Pommier
Publikováno v:
Epigenetics & Chromatin, Vol 13, Iss 1, Pp 1-13 (2020)
Abstract Background Next-generation sequencing allows genome-wide analysis of changes in chromatin states and gene expression. Data analysis of these increasingly used methods either requires multiple analysis steps, or extensive computational time.
Externí odkaz:
https://doaj.org/article/b9ba48dd06a743eb8bd1a06c73e19853
Autor:
Rocío M. Gamez, Fernando Rodríguez, Newton Medeiros Vidal, Sandra Ramirez, Roberto Vera Alvarez, David Landsman, Leonardo Mariño-Ramírez
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-20 (2019)
Abstract Background Banana is one of the most important crops in tropical and sub-tropical regions. To meet the demands of international markets, banana plantations require high amounts of chemical fertilizers which translate into high farming costs
Externí odkaz:
https://doaj.org/article/f625d4bf1f2f42939f75a231d57141e2
Autor:
Ning Zhang, Yuting Chen, Haoyu Lu, Feiyang Zhao, Roberto Vera Alvarez, Alexander Goncearenco, Anna R. Panchenko, Minghui Li
Publikováno v:
iScience, Vol 23, Iss 3, Pp - (2020)
Summary: Missense mutations may affect proteostasis by destabilizing or over-stabilizing protein complexes and changing the pathway flux. Predicting the effects of stabilizing mutations on protein-protein interactions is notoriously difficult because
Externí odkaz:
https://doaj.org/article/a8375d63c2394331adf0d18d1fe73984
Autor:
Roberto Vera Alvarez, David Landsman
Multiple next-generation-sequencing (NGS)-based studies are enabled by the availability of a reference genome of the target organism. Unfortunately, several organisms remain unannotated due to the cost and complexity of generating a complete (or clos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd786dd7b4d19f6facfe7af45ba8f9d5
https://doi.org/10.1101/2022.11.07.515468
https://doi.org/10.1101/2022.11.07.515468
Autor:
Manoj Kumar Kashyap, Hiren Karathia, Deepak Kumar, Roberto Vera Alvarez, Paula A Lengerke-Diaz, Jose Vicente Forero-Forero, Eider Moreno, Juliana Velez Lujan, Carlos Ivan Amaya-Chanaga, Newton Medeiros Vidal, Zhe Yu, Daniel Achinko, Emanuela M. Ghia, Michael Y. Choi, Laura Z. Rassenti, Leonardo Mariño-Ramírez, Stephen M. Mount, Sridhar Hannenhalli, Thomas J. Kipps, Januario E. Castro
BackgroundAlternative splicing (AS) is a fundamental process in eukaryotes contributing to the diversity of mRNA isoforms with variable ratios of intron/exon. SF3B1 is a pivotal protein of the spliceosome machinery. Mutations in the SF3B1 gene have p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9780fc833c4337eeaff49ae6153d3bf
https://doi.org/10.21203/rs.3.rs-1622375/v1
https://doi.org/10.21203/rs.3.rs-1622375/v1
Publikováno v:
J Bacteriol
The current classification of the phylum Firmicutes (new name, Bacillota) features eight distinct classes, six of which include known spore-forming bacteria. In Bacillus subtilis, sporulation involves up to 500 genes, many of which do not have orthol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc7e7fdbd3a5333e05118b931e42f4d4
https://doi.org/10.1101/2022.02.25.481979
https://doi.org/10.1101/2022.02.25.481979
Autor:
Sofya K. Garushyants, Michael Y. Galperin, Roberto Vera Alvarez, Yuri I. Wolf, Eugene V. Koonin
Publikováno v:
J Bacteriol
Ribosomal proteins (RPs) are highly conserved across the bacterial and archaeal domains. Although many RPs are essential for survival, genome analysis demonstrates the absence of some RP genes in many bacterial and archaeal genomes. Furthermore, glob