Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Roberto Tira"'
Autor:
Carlo Giorgio Barracchia, Roberto Tira, Francesca Parolini, Francesca Munari, Luigi Bubacco, Georgios A. Spyroulias, Mariapina D’Onofrio, Michael Assfalg
Publikováno v:
Molecules, Vol 25, Iss 11, p 2716 (2020)
Background: The intrinsically disordered, amyloidogenic protein Tau associates with diverse classes of molecules, including proteins, nucleic acids, and lipids. Mounting evidence suggests that fatty acid molecules could play a role in the dysfunction
Externí odkaz:
https://doaj.org/article/42e1df25def4428b8a27111e6a65d7aa
Autor:
Francesca Munari, Carlo Giorgio Barracchia, Francesca Parolini, Roberto Tira, Luigi Bubacco, Michael Assfalg, Mariapina D’Onofrio
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 12, p 4400 (2020)
Ubiquitin, a protein modifier that regulates diverse essential cellular processes, is also a component of the protein inclusions characteristic of many neurodegenerative disorders. In Alzheimer’s disease, the microtubule associated tau protein accu
Externí odkaz:
https://doaj.org/article/7f249eba4ff444bc8e0e9d87a528c646
Autor:
Fernando D. López León, Roger Bravo Neyra, Roberto H. Tirado Malaver, Fredesvindo Fernández Herrera, Roberto Tirado-Lara, Felix Bustamante-Bustamante, Edson M. Caro-Degollar, Angel Campos Julca
Publikováno v:
Chemical Engineering Transactions, Vol 111 (2024)
To extend the shelf life and make efficient use of the fruit requires industrial processing, transforming the fresh fruit into a dehydrated product. Therefore, the objective of this research was to determine the optimal technological process for the
Externí odkaz:
https://doaj.org/article/201ff0e8dcf44d1b85e1d661ebdca02f
Autor:
Carlo Giorgio Barracchia, Giuseppe Legname, Michael Assfalg, Rita Grandori, Alessandro Romeo, Roberto Tira, Francesca Munari, Davide Prosperi, Carlo Santambrogio, Elena De Cecco, Valentina Rigamonti
Publikováno v:
International Journal of Biological Macromolecules. 154:206-216
The notion that nanoscale surfaces influence protein conformational transitions stimulates the investigation of fibrillogenic polypeptides adsorbing to nanomaterials. Alpha-synuclein (αS) is a prototypical amyloidogenic protein whose aggregation is
Autor:
Giovanna Viola, Carlo Giorgio Barracchia, Roberto Tira, Francesca Parolini, Giulia Leo, Massimo Bellanda, Francesca Munari, Stefano Capaldi, Mariapina D’Onofrio, Michael Assfalg
Understanding the interactions between nanoparticles (NPs) and proteins is crucial for the successful application of NPs in biological contexts. Protein adsorption is dependent on particle size, and protein binding to ultrasmall (1-3 nm) NPs is consi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3313a0de7b831443144ce51f25a5738b
https://hdl.handle.net/11562/1077886
https://hdl.handle.net/11562/1077886
Autor:
Francesca Parolini, Roberto Tira, Carlo Giorgio Barracchia, Francesca Munari, Stefano Capaldi, Mariapina D'Onofrio, Michael Assfalg
The formation of biomolecular condensates has emerged as a crucial player both in neuronal physiology and neurodegeneration. Phase separation of the Alzheimer's related protein tau into liquid condensates is facilitated by polyanions and is regulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24ca7c5597522b86daa019a71db973e0
http://hdl.handle.net/11562/1059160
http://hdl.handle.net/11562/1059160
Autor:
Luigi Bubacco, Francesca Munari, Michael Assfalg, Mariapina D'Onofrio, Carlo Giorgio Barracchia, Francesca Parolini, Roberto Tira
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 12
International Journal of Molecular Sciences, Vol 21, Iss 4400, p 4400 (2020)
Volume 21
Issue 12
International Journal of Molecular Sciences, Vol 21, Iss 4400, p 4400 (2020)
Ubiquitin, a protein modifier that regulates diverse essential cellular processes, is also a component of the protein inclusions characteristic of many neurodegenerative disorders. In Alzheimer&rsquo
s disease, the microtubule associated tau pro
s disease, the microtubule associated tau pro
Autor:
Roberto Hugo Tirado Malaver, Roberto Tirado-Lara, Juan Mendoza-Cortez, Nayla Fabian-Anastacio, Ronald Tirado-Malaver, Angel Campos-Julca
Publikováno v:
Tropical and Subtropical Agroecosystems, Vol 27, Iss 1 (2023)
Background: Potato cultivation in the northern highlands of Peru has intensified due to the high demand of the national market for the nutritional quality of this tuber, however, the conventional system presents critical points in social, economic an
Externí odkaz:
https://doaj.org/article/c7fdaa0fd0874bd5bbeaa86089d75946
Autor:
Sock Hoai Chan, Yasmin Bylstra, Jing Xian Teo, Jyn Ling Kuan, Nicolas Bertin, Mar Gonzalez-Porta, Maxime Hebrard, Roberto Tirado-Magallanes, Joanna Hui Juan Tan, Justin Jeyakani, Zhihui Li, Jin Fang Chai, Yap Seng Chong, Sonia Davila, Liuh Ling Goh, Eng Sing Lee, Eleanor Wong, Tien Yin Wong, SG10K_Health Consortium, Shyam Prabhakar, Jianjun Liu, Ching-Yu Cheng, Birgit Eisenhaber, Neerja Karnani, Khai Pang Leong, Xueling Sim, Khung Keong Yeo, John C. Chambers, E-Shyong Tai, Patrick Tan, Saumya S. Jamuar, Joanne Ngeow, Weng Khong Lim
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Clinically significant genetic variation in Asian populations is under-characterized. Here, the authors show the diversity in prevalence and spectrum of human disease and pharmacogenetic variants in a multi-ethnic Asian population.
Externí odkaz:
https://doaj.org/article/117b09c793b9435cbcba4527a4883feb
Autor:
William Cross, Iben Lyskjær, Tom Lesluyes, Steven Hargreaves, Anna-Christina Strobl, Christopher Davies, Sara Waise, Shadi Hames-Fathi, Dahmane Oukrif, Hongtao Ye, Fernanda Amary, Roberto Tirabosco, Craig Gerrand, Toby Baker, David Barnes, Christopher Steele, Ludmil Alexandrov, Gareth Bond, Genomics England Research Consortium, Paul Cool, Nischalan Pillay, Peter Van Loo, Adrienne M. Flanagan
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-12 (2022)
Abstract Background Central conventional chondrosarcoma (CS) is the most common subtype of primary malignant bone tumour in adults. Treatment options are usually limited to surgery, and prognosis is challenging. These tumours are characterised by the
Externí odkaz:
https://doaj.org/article/ffacb8a0eb7048c79fcc4c60653e1002