Zobrazeno 1 - 10 of 128 pro vyhledávání: '"Roberto T Sudo"'
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Akademický článek
Synergistic interaction between a PDE5 inhibitor (sildenafil) and a new adenosine A2A receptor agonist (LASSBio-1359) improves pulmonary hypertension in rats.
Autor: Allan K Alencar, Fábio I Carvalho, Ananssa M Silva, Sabrina T Martinez, Jorge A Calasans-Maia, Carlos M Fraga, Eliezer J Barreiro, Gisele Zapata-Sudo, Roberto T Sudo
Publikováno v: PLoS ONE, Vol 13, Iss 4, p e0195047 (2018)
Pulmonary hypertension (PH) is characterized by enhanced pulmonary vascular resistance, which causes right ventricle (RV) pressure overload and results in right sided heart failure and death. This work investigated the effectiveness of a combined the
Externí odkaz: https://doaj.org/article/6f26495eb6ac41b2a7cebda365ef1c25
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2
Antinociceptive Effect of Lodenafil Carbonate in Rodent Models of Inflammatory Pain and Spinal Nerve Ligation-Induced Neuropathic Pain
Autor: Marcio Carneiro Vieira, Fernanda Bezerra de Mello Monte, Jaqueline S da Silva, Guilherme C Montes, Rosalia Mendez-Otero, Tadeu L Montagnoli, Bruno Eduardo Dematte, Margarete M. Trachez, Gisele Zapata-Sudo, Roberto T. Sudo
Publikováno v: Journal of Pain Research
Marcio Carneiro Vieira,1,2 Fernanda Bezerra de Mello Monte,3 Bruno Eduardo Dematte,3 Tadeu Lima Montagnoli,3 Guilherme Carneiro Montes,3 Jaqueline Soares da Silva,3 Rosalia Mendez-Otero,4 Margarete Manhães Trachez,3 Roberto Takashi Sudo,1,3 Gisele Z
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d4f4a2f987a02472666e16b2f44566c
https://doi.org/10.2147/jpr.s295265
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3
New Benzofuran N-Acylhydrazone Reduces Cardiovascular Dysfunction in Obese Rats by Blocking TNF-Alpha Synthesis
Autor: Marina M. Silva, Gizele Cabral Costa, Eliezer J. Barreiro, Tadeu L Montagnoli, Pedro M. Pimentel-Coelho, Luis Eduardo Reina Gamba, Bryelle Eccard De Oliveira Alves, Margarete M. Trachez, José Nascimento, Roberto T. Sudo, Gisele Zapata-Sudo, Jaqueline S da Silva, Lídia Moreira Lima, Rosalia Mendez-Otero, Allan K Alencar
Publikováno v: Drug Design, Development and Therapy. 14:3337-3350
Introduction Diabetic obese patients are susceptible to the development of cardiovascular disease, including hypertension and cardiac dysfunction culminating in diabetic cardiomyopathy (DC), which represents a life-threatening health problem with inc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b97accd7d043ada73cbaadca6ec3a0ef
https://doi.org/10.2147/dddt.s258459
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5
G-Protein–Coupled Estrogen Receptor Agonist G1 Improves Diastolic Function and Attenuates Cardiac Renin–Angiotensin System Activation in Estrogen-Deficient Hypertensive Rats
Autor: Leanne Groban, Hao Wang, Jaqueline S da Silva, Roberto T. Sudo, Xuming Sun, Gisele Zapata-Sudo, Jasmina Varagic, Carlos M. Ferrario, Sarfaraz Ahmad
Publikováno v: Journal of Cardiovascular Pharmacology. 74:443-452
This study was aimed to clarify differences in how specific agonists of the 3 estrogen receptors (ERs) influence diastolic function and the renin-angiotensin system (RAS) after ovariectomy (OVX) in 24 female spontaneously hypertensive rat (SHR) under
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff42c8f7b2c0be04b926497860cad6a
https://doi.org/10.1097/fjc.0000000000000721
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6
Cardiac electrical and contractile disorders promoted by anabolic steroid overdose are associated with late autonomic imbalance and impaired Ca2+ handling
Autor: Raiana A. Q. Barbosa, Roberto T. Sudo, Paulo C. Arantes, Ainá E. Domingos, Fernando A.C. Seara, José Nascimento, Antonio Carlos Carvalho, Emerson L. Olivares
Publikováno v: Steroids. 148:1-10
Aim Investigate cardiac electrical and mechanical dysfunctions elicited by chronic anabolic steroid (AS) overdose. Methods Male Wistar rats were treated with nandrolone decanoate (DECA) or vehicle (CTL) for 8 weeks. Electrocardiography and heart rate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::53471e8a22ab2958569c46c9a8014acc
https://doi.org/10.1016/j.steroids.2019.04.001
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7
Pulmonary hypertension: reduction of vascular and cardiac remodeling by a new inhibitor of p38-alpha MAPK
Autor: Bass Rocha, Tadeu L Montagnoli, Rosana H. C. N. Freitas, Gisele Zapata-Sudo, Carlos A. M. Fraga, Gustavo Silva, Roberto T. Sudo, F Beltrame, J.S. da Silva, Allan K N Alencar, Mondino Silva
Publikováno v: European Heart Journal. 41
Background Pulmonary arterial hypertension (PAH) is a disease characterized by pulmonary vascular remodeling with subsequent right ventricular (RV) failure. This work investigated the effects of a new p38-alpha mitogen-activated protein kinase (p38-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::61b6e404285e31ecf2f40a301a906898
https://doi.org/10.1093/ehjci/ehaa946.3803
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8
Therapeutic Benefit of the Association of Lodenafil with Mesenchymal Stem Cells on Hypoxia-induced Pulmonary Hypertension in Rats
Autor: Roberto T. Sudo, Gisele Zapata-Sudo, Bruna S Rocha, Allan K Alencar, Pedro M. Pimentel-Coelho, Juliana Ferreira Vasques, Marina M. Silva, Jaqueline S da Silva, Tadeu L Montagnoli, Grazielle F Silva, Margarete Manhães Trahez, Rosalia Mendez-Otero, Guilherme C Montes
Publikováno v: Cells, Vol 9, Iss 2120, p 2120 (2020)
Cells
Volume 9
Issue 9
Pulmonary arterial hypertension (PAH) is characterized by the remodeling of pulmonary arteries, with an increased pulmonary arterial pressure and right ventricle (RV) overload. This work investigated the benefit of the association of human umbilical
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d986ad5abbb364a5a5ad4d861e952ad2
https://www.mdpi.com/2073-4409/9/9/2120
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9
Novel agonist of α4β2* neuronal nicotinic receptor with antinociceptive efficacy in rodent models of acute and chronic pain
Autor: Margarete M. Trachez, Gisele Zapata-Sudo, Roberto T. Sudo, Guilherme C Montes, Ken-ichiro Hayashida, Masahito Kawatani, Carlos Es Monteiro, Roberto D Moreira, Aluízio N Santos
Publikováno v: Journal of Pain Research. 11:2453-2462
Objective To demonstrate the antinociceptive and antihypersensitivity mechanisms of Cris-104 (1-{2-[5-(4-fluorophenyl)-1H-pyrazol-4-yl]ethyl}piperidine), a novel selective α4β2* nicotinic acetylcholine receptor (nAChR) agonist, in rodent acute/infl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::de264314965b6d7ce75c9985c77ddb5f
https://doi.org/10.2147/jpr.s169637
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10
O-GlcNAcylation reduces proximal tubule protein reabsorption and promotes proteinuria in spontaneously hypertensive rats
Autor: Christina Maeda Takiya, Wagner B. Dias, Miguel C. Lucena, Celso Caruso-Neves, Gisele Zapata-Sudo, Rodrigo P. Silva-Aguiar, Gabriela Modenesi Sirtoli, Nathália C.F. Bezerra, Roberto T. Sudo, Ana Acacia S. Pinheiro
Publikováno v: Journal of Biological Chemistry. 293:12749-12758
Hypertensive individuals are at greater risk for developing chronic kidney disease (CKD). Reducing proteinuria has been suggested as a possible therapeutic approach to treat CKD. However, the mechanisms underlying the development of proteinuria in hy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd0958f8dca7c950f8460471a398c3c
https://doi.org/10.1074/jbc.ra118.001746
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