Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Roberto Staffolani"'
Activation of human aortic endothelial cells by LDL from Type 1 diabetic patients: an in vitro study
Autor:
Natalia Moretti, Laura Mazzanti, D. Martarelli, Roberto Staffolani, Rosa Anna Rabini, Arianna Vignini, Eleonora Salvolini
Publikováno v:
Atherosclerosis. 165:69-77
An altered interaction between circulating LDL and endothelial cells might be at the basis of the increased prevalence of atherosclerosis in diabetes mellitus. The aim of the present work was to investigate the effect of a short incubation period wit
Autor:
Roberto Staffolani, Nelvio Cester, Daniele Fumelli, Laura Mazzanti, Natalia Moretti, Eleonora Salvolini, Arianna Vignini, Rosa Anna Rabini
Publikováno v:
Diabetes. 48:2221-2228
The aim of the present work was to analyze the effect of LDL obtained from type 1 diabetic patients in good metabolic control on human umbilical vein endothelial cells (HUVECs) after a short incubation period to detect possible atherogenic modificati
Autor:
D. Martarelli, Laura Mazzanti, Giovanna Curatola, M. A. Camilloni, F. Mantero, G. Lucarelli, G. G. M. Garrapa, Emanuela Faloia, Roberto Staffolani
Publikováno v:
European Journal of Clinical Investigation. 29:432-437
Background Na+,K+-ATPase activity was evaluated in relation to membrane composition and molecular organization in erythrocyte membranes from obese patients by the amphyphylic molecule 6-dodecanoyl-2-dimethylamino-naphthalene (Laurdan). Its possible r
Autor:
Ileana Giambanco, Enrico Gratton, Roberto Staffolani, Rosario Donato, Giovanna Curatola, Giovanna Zolese
Publikováno v:
Cell Calcium. 20:465-474
Phase-modulation fluorescence lifetime measurements were used to study the single Trp residue of the Ca(2+)-binding protein S-100a both in the absence and in the presence of Ca2+ and/or Mg2+. Trp fluorescence decay for the protein was satisfactorily
Autor:
Rosa Anna Rabini, Laura Mazzanti, Eleonora Salvolini, Graziella Biagini, Armanda Pugnaloni, Cester N, Garzetti Gg, L. Simonelli, Roberto Staffolani
Publikováno v:
Experimental and Molecular Pathology. 63:175-185
A platelet (PLT) function modification has been reported in normal pregnancies compared with the nonpregnant condition and it has been hypothesized to play a central role in the pathogenesis of pregnancy-induced hypertension (PIH). The aims of the pr
Autor:
Armanda Pugnaloni, Rosa Anna Rabini, Eleonora Salvolini, Nelvio Cester, Graziella Biagini, Laura Mazzanti, C. Rizzoli, Roberto Staffolani, Carlo Romanini
Publikováno v:
Hypertension in Pregnancy. 14:227-234
Objective: The study examined the effects of salt-induced hypertension on vascular contractile responses during pregnancy and the mechanisms of the effects.Methods: Aortic rings from pregnant Wistar rats, fed for 6 weeks on diets containing 0.3% (con
Autor:
Ivano Testa, Mauro Polenta, Laura Mazzanti, Massimo Tocchini, Roberto Signore, Roberto Staffolani, Rosa Anna Rabini
Publikováno v:
Experimental and Molecular Pathology. 59:51-57
We studied 56 patients affected by primary hypercholesterolemia treated with placebo for 1 month and with simvastatin (20 mg/day) or pravastatin (20 mg/day) for 6 months during a double-blind clinical trial. At 1-month intervals we determined the fol
Autor:
Roberto Staffolani, Laura Mazzanti, R. De Pirro, Paolo Fumelli, Emanuela Faloia, Armanda Pugnaloni, Rosa Anna Rabini, G. Biagint
Publikováno v:
Membrane Biochemistry. 10:71-79
Diabetic patients present alterations in the activity of a number of enzymes of the plasma membrane. The aim of this study was to verify if the modifications of the enzymatic activities in diabetes mellitus are associated with structural alterations
Autor:
Roberto Staffolani, Rosa Anna Rabini, Roberto De Pirro, Emanuela Faloia, A. M. Cugini, Carlo Romanini, Laura Mazzanti, Nelvio Cester
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1139:65-69
The pathogenesis of plasma membrane alterations present in diabetes mellitus is unclear. To add new insights to the question, platelet membrane properties were evaluated in 16 women presenting impaired glucose tolerance at the 28–29th week of gesta
Autor:
A. M. Cugini, Emanuela Faloia, Rosa Anna Rabini, Roberto Staffolani, R. De Pirro, Nelvio Cester, Laura Mazzanti, Carlo Romanini, G. Benedetti
Publikováno v:
Scandinavian Journal of Clinical and Laboratory Investigation. 51:405-410
Alterations in erythrocyte plasma membrane properties (enzymatic activities and membrane fluidity) have been observed in patients affected by insulin-dependent diabetes mellitus (IDDM) and non-insulin-dependent diabetes mellitus (NIDDM). In order to