Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Roberto Speziale"'
Autor:
Roberto Speziale, Camilla Montesano, Giulia Di Pietro, Daniel Oscar Cicero, Vincenzo Summa, Edith Monteagudo, Laura Orsatti
Publikováno v:
Metabolites, Vol 13, Iss 8, p 961 (2023)
Huntington’s disease (HD) is caused by the expansion of a polyglutamine (polyQ)-encoding tract in exon 1 of the huntingtin gene to greater than 35 CAG repeats. It typically has a disease course lasting 15–20 years, and there are currently no dise
Externí odkaz:
https://doaj.org/article/7a92756f06cd4e50be6195e730b03141
Autor:
Laura Orsatti, Thomas Stiehl, Katharina Dischinger, Roberto Speziale, Pamela Di Pasquale, Edith Monteagudo, Carsten Müller-Tidow, Aleksandar Radujkovic, Peter Dreger, Thomas Luft
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 10, Pp 100409- (2021)
Summary: Fibrosing chronic graft-versus-host disease (cGVHD) is a debilitating complication of allogeneic stem cell transplantation (alloSCT). A driver of fibrosis is the kynurenine (Kyn) pathway, and Kyn metabolism patterns and cytokines may influen
Externí odkaz:
https://doaj.org/article/dd8f78204321413ba3f5a727df27aac9
Autor:
Greta Petrella, Camilla Montesano, Sara Lentini, Giorgia Ciufolini, Domitilla Vanni, Roberto Speziale, Andrea Salonia, Francesco Montorsi, Vincenzo Summa, Riccardo Vago, Laura Orsatti, Edith Monteagudo, Daniel Oscar Cicero
Publikováno v:
Molecules, Vol 26, Iss 14, p 4167 (2021)
A new strategy that takes advantage of the synergism between NMR and UHPLC–HRMS yields accurate concentrations of a high number of compounds in biofluids to delineate a personalized metabolic profile (SYNHMET). Metabolite identification and quantif
Externí odkaz:
https://doaj.org/article/909a2745bb8f4e96a349ad3eb10de1c9
Autor:
Carsten Müller-Tidow, Thomas Luft, Roberto Speziale, Thomas Stiehl, Laura Orsatti, Aleksandar Radujkovic, Katharina Dischinger, Peter Dreger, Edith Monteagudo, Pamela Di Pasquale
Publikováno v:
Cell reports 2(10), 100409 (2021). doi:10.1016/j.xcrm.2021.100409
Cell Reports Medicine
Cell Reports Medicine, Vol 2, Iss 10, Pp 100409-(2021)
Cell Reports Medicine
Cell Reports Medicine, Vol 2, Iss 10, Pp 100409-(2021)
Summary Fibrosing chronic graft-versus-host disease (cGVHD) is a debilitating complication of allogeneic stem cell transplantation (alloSCT). A driver of fibrosis is the kynurenine (Kyn) pathway, and Kyn metabolism patterns and cytokines may influenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::495108ade46a9cf16537e41d8e6b30ad
https://publications.rwth-aachen.de/record/846567
https://publications.rwth-aachen.de/record/846567
Autor:
Daniel Elbaum, Maria Lucia de Leonibus, Camilla Montesano, Laura Orsatti, Fabio Bonelli, Maria G. Beconi, Roberto Speziale, Edith Monteagudo, Paola Fezzardi
Publikováno v:
Journal of Chromatography B. 1083:57-62
Acetyl coenzyme A is involved in several key metabolic pathways. Its concentration can vary considerably in response to physiological or pathological conditions making it a potentially valuable biomarker. However, little information about the measure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d54c9f1c055ecb654eea743e3e2556b
https://doi.org/10.1016/j.jchromb.2018.02.039
https://doi.org/10.1016/j.jchromb.2018.02.039
Autor:
Pamela Di Pasquale, Roberto Speziale, Orsatti Laura, Aleksandar Radujkovic, Carsten Mueller-Tidow, Thomas Stiehl, Katharina Dischinger, Edith Monteagudo, Thomas Luft, Peter Dreger
Publikováno v:
Blood. 138:3895-3895
Background: Fibrosing chronic graft-versus-host disease (cGVHD) is a debilitating complication after allogeneic stem cell transplantation (allo-SCT), and its pathophysiology is poorly understood. Kynurenine and its metabolites were shown to associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f546f6bdeb10bcca70339631f3a30317
https://doi.org/10.1182/blood-2021-152793
https://doi.org/10.1182/blood-2021-152793
Autor:
Laura Orsatti, Roberto Speziale, Kathryn A. Lyons, Fulvia Caretti, Maria Vittoria Orsale, Edith Monteagudo, Maria G. Beconi, Fabio Bonelli, Maria Veneziano, Todd Herbst, Ignacio Munoz-Sanjuan, Celia Dominguez, Matteo Zini, Kelvin Chan, Leticia Toledo-Sherman
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 107:426-431
Neuroactive metabolites in the kynurenine pathway of tryptophan catabolism are associated with neurodegenerative disorders. Tryptophan is transported across the blood–brain barrier and converted via the kynurenine pathway to N-formyl- l -kynurenine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4572036f528eeda5c4833d5434d89f0d
https://doi.org/10.1016/j.jpba.2015.01.030
https://doi.org/10.1016/j.jpba.2015.01.030
Extraction and analysis of fungal spore biomarkers in atmospheric bioaerosol by HPLC–MS–MS and GC–MS
Autor:
Carmela Riccardi, Donatella Pomata, Francesca Buiarelli, Patrizia Di Filippo, Silvia Canepari, Cinzia Perrino, Roberto Speziale
Publikováno v:
Talanta. 105:142-151
Airborne microorganisms, as bacteria and fungi, are ubiquitous components of the atmospheric aerosol particles. In this paper, we report a method for the simultaneous extraction, purification, separation, identification and quantification of ergoster
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77999588e097819f33256c19cf20ad49
https://doi.org/10.1016/j.talanta.2012.11.006
https://doi.org/10.1016/j.talanta.2012.11.006
Autor:
Martina Nibbio, Roberto Speziale, Simone Esposito, Laura Orsatti, Edith Monteagudo, Maria Veneziano, Fabio Bonelli, Elena Bracacel
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 118
This work describes a simple, sensitive and rapid liquid chromatography-high resolution mass spectrometry method for the quantitation of perhexiline and the simultaneous detection of perhexiline metabolites in C57bl/6 mice plasma. Only 5 μL of plasm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::533cee6b005931b1ccee7c7d68bcca01
https://pubmed.ncbi.nlm.nih.gov/26517851
https://pubmed.ncbi.nlm.nih.gov/26517851