Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Roberto Spada"'
Autor:
Roberto Spada, Domingo Barber
Publikováno v:
Bio-Protocol, Vol 6, Iss 5 (2016)
NKG2D is expressed on all NK cells and on subsets of NKT, CD8, CD4 and γδ T cells. NKG2D is activated by NKG2D ligands, a stress-induced family of MHC-I-like proteins. These ligands are upregulated on stressed/infected cells and are not widely expr
Externí odkaz:
https://doaj.org/article/9cfe9f04a0584126be9c0fa449eb80a6
Autor:
Teresa M Zotes, Roberto Spada, Vladimir Mulens, Sonia Pérez-Yagüe, Carlos O Sorzano, Klaus Okkenhaug, Ana C Carrera, Domingo F Barber
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72960 (2013)
The role of p110δ PI3K in lymphoid cells has been studied extensively, showing its importance in immune cell differentiation, activation and development. Altered T cell localization in p110δ-deficient mouse spleen suggested a role for p110δ in non
Externí odkaz:
https://doaj.org/article/ff79f65af05b4a6b8c5b2ecb16c54709
Autor:
Teresa M Zotes, Cristina F Arias, José J Fuster, Roberto Spada, Sonia Pérez-Yagüe, Emilio Hirsch, Matthias Wymann, Ana C Carrera, Vicente Andrés, Domingo F Barber
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72674 (2013)
Atherosclerosis is an inflammatory disease regulated by infiltrating monocytes and T cells, among other cell types. Macrophage recruitment to atherosclerotic lesions is controlled by monocyte infiltration into plaques. Once in the lesion, macrophage
Externí odkaz:
https://doaj.org/article/ded248cc842d4a938df200b5578127f5
Autor:
Raquel Mejías, Laura Morillas, Laura Sanz-Ortega, Roberto Spada, Domingo F. Barber, Sonia Pérez-Yagüe, José M. Rojas, Vladimir Mulens-Arias
Publikováno v:
Journal of Leukocyte Biology. 100:1285-1296
Activation of NK cells depends on a balance between activating and inhibitory signals. Class Ia PI3K are heterodimeric proteins with a catalytic and a regulatory subunit and have a central role in cell signaling by associating with tyrosine kinase re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b234bb8e8544026c30b8f71e03ebcff
https://doi.org/10.1189/jlb.1a1215-541rr
https://doi.org/10.1189/jlb.1a1215-541rr
Autor:
Carlos Oscar S. Sorzano, Ana C. Carrera, Domingo F. Barber, Klaus Okkenhaug, Teresa M. Zotes, Roberto Spada, Vladimir Mulens, Sonia Pérez-Yagüe
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 8, p e72960 (2013)
PLoS ONE, Vol 8, Iss 8, p e72960 (2013)
The role of p110δ PI3K in lymphoid cells has been studied extensively, showing its importance in immune cell differentiation, activation and development. Altered T cell localization in p110δ-deficient mouse spleen suggested a role for p110δ in non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c700c6d9adf54491630c8d78c3af289
Autor:
Domingo F. Barber, Roberto Spada
Publikováno v:
BIO-PROTOCOL. 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e54982d91af389e8c9cd512195c0342
https://doi.org/10.21769/bioprotoc.1754
https://doi.org/10.21769/bioprotoc.1754
Autor:
Lucía Gutiérrez, Lourdes I. Cabrera, Roberto Spada, Raquel Mejías, María del Puerto Morales, Domingo F. Barber, Sonia Pérez-Yagüe, Angeles Villanueva, Carlos J. Serna, Pilar Acedo, Francisco J. Lázaro
Publikováno v:
Biomaterials. 32:2938-2952
As radio- and chemotherapy-based cancer treatments affect both tumors and healthy tissue, cancer immunotherapy attempts to specifically enhance the natural immune response to tumor cells. In mouse models of cancer, we tested uniform dimercaptosuccini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7071cc815f025c406f513e7521654cf
https://doi.org/10.1016/j.biomaterials.2011.01.008
https://doi.org/10.1016/j.biomaterials.2011.01.008
Publikováno v:
Journal of leukocyte biology. 98(4)
Systemic lupus erythematosus is a chronic, multifactorial autoimmune disease of complex etiology, characterized by loss of tolerance to nuclear autoantigens, expansion of autoreactive T and B cell clones, polyclonal B cell activation that gives rise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b93e5e49155c910b0e3a351706f6f397
https://pubmed.ncbi.nlm.nih.gov/26216938
https://pubmed.ncbi.nlm.nih.gov/26216938
Autor:
Vladimir Mulens, Pablo Cannata-Ortiz, Rafael Bragado, Sonia Pe´rez-Yagu¨e, Domingo F. Barber, José M. Rojas, Roberto Spada
NK cells are a major component of the immune system, and alterations in their activity are correlated with various autoimmune diseases. In the present work, we observed an increased expression of the NKG2D ligand MICA in SLE patients’ kidneys but n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c2f97f643da43822c46ce754f0e883
https://europepmc.org/articles/PMC5477896/
https://europepmc.org/articles/PMC5477896/