Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Roberto Ruiu"'
Autor:
Roberto Ruiu, Chiara Cossu, Antonella Iacoviello, Laura Conti, Elisabetta Bolli, Luca Ponzone, Jolanda Magri, Alekya Rumandla, Enzo Calautti, Federica Cavallo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-16 (2023)
Abstract Background The upregulation of antioxidant mechanisms is a common occurrence in cancer cells, as they strive to maintain balanced redox state and prevent oxidative damage. This includes the upregulation of the cystine/glutamate antiporter xC
Externí odkaz:
https://doaj.org/article/13f8c99deeec400184da758ebeb3e721
Autor:
Antonino Di Lorenzo, Elisabetta Bolli, Roberto Ruiu, Giuseppe Ferrauto, Enza Di Gregorio, Lidia Avalle, Aurora Savino, Pietro Poggio, Irene Fiore Merighi, Federica Riccardo, Mara Brancaccio, Elena Quaglino, Federica Cavallo, Laura Conti
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Cancer stem cells (CSCs) are the main drivers of disease progression and chemotherapy resistance in breast cancer. Tumor progression and chemoresistance might then be prevented by CSC-targeted therapies. We previously demonstrated that Toll-like Rece
Externí odkaz:
https://doaj.org/article/4d7f2d53f71c4553ae2ce00f7fd2960b
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
There is substantial evidence to suggest that complete tumor eradication relies on the effective elimination of cancer stem cells (CSCs). CSCs have been widely described as mediators of resistance to conventional therapies, including chemo- and radio
Externí odkaz:
https://doaj.org/article/8184b94309734dd98317860b01812f27
Autor:
Maria Rosaria Ruggiero, Simona Baroni, Valeria Bitonto, Roberto Ruiu, Smeralda Rapisarda, Silvio Aime, Simonetta Geninatti Crich
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
This study aims to explore whether the water exchange rate constants in tumor cells can act as a hallmark of pathology status and a reporter of therapeutic outcomes. It has been shown, using 4T1 cell cultures and murine allografts, that an early asse
Externí odkaz:
https://doaj.org/article/e704e27b3e7d4c89a99602ff6b0019b6
Autor:
Gaetano Donofrio, Giulia Tebaldi, Stefania Lanzardo, Roberto Ruiu, Elisabetta Bolli, Andrea Ballatore, Valeria Rolih, Francesca Macchi, Laura Conti, Federica Cavallo
Publikováno v:
OncoImmunology, Vol 7, Iss 12 (2018)
Despite marked advancements in its treatment, breast cancer is still the second leading cause of cancer death in women, due to relapses and distal metastases. Breast cancer stem cells (CSCs), are a cellular reservoir for recurrence, metastatic evolut
Externí odkaz:
https://doaj.org/article/cbf699c797e0459f84a82bb7480827b6
Autor:
Roberto Ruiu, Giuseppina Barutello, Maddalena Arigoni, Federica Riccardo, Laura Conti, Giulia Peppino, Laura Annaratone, Caterina Marchiò, Giulio Mengozzi, Raffaele Adolfo Calogero, Federica Cavallo, Elena Quaglino
Publikováno v:
Cancers, Vol 13, Iss 4, p 894 (2021)
Triple-negative breast cancer (TNBC) is insensitive to endocrine and Her2-directed therapies, making the development of TNBC-targeted therapies an unmet medical need. Since patients with TNBC frequently show a quicker relapse and metastatic progressi
Externí odkaz:
https://doaj.org/article/7798cdbfc1b04c6ba534bec61e9e4348
Autor:
Giulia Peppino, Roberto Ruiu, Maddalena Arigoni, Federica Riccardo, Antonella Iacoviello, Giuseppina Barutello, Elena Quaglino
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2321 (2021)
Teneurins have been identified in vertebrates as four different genes (TENM1-4), coding for membrane proteins that are mainly involved in embryonic and neuronal development. Genetic studies have correlated them with various diseases, including develo
Externí odkaz:
https://doaj.org/article/93d0292a347a44488a1ebf9639cd40af
Autor:
Jolanda Magri, Alessandro Gasparetto, Laura Conti, Enzo Calautti, Chiara Cossu, Roberto Ruiu, Giuseppina Barutello, Federica Cavallo
Publikováno v:
Cells, Vol 10, Iss 1, p 108 (2021)
The cystine/glutamate antiporter xCT is a tumor-associated antigen that has been newly identified in many cancer types. By participating in glutathione biosynthesis, xCT protects cancer cells from oxidative stress conditions and ferroptosis, and cont
Externí odkaz:
https://doaj.org/article/26bf418ef18342478b6b709c47443fdb
Autor:
Federica Cavallo, Gaetano Donofrio, Elena Quaglino, Luca Russo, Roberto Ruiu, Federica Riccardo, Francesca Macchi, Valentina Franceschi, Antonino Di Lorenzo, Elisabetta Bolli, Laura Conti
Figure S5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10a2189105318bdb46d5b40ac3e42549
https://doi.org/10.1158/2326-6066.22544032
https://doi.org/10.1158/2326-6066.22544032
Autor:
Federica Cavallo, Gaetano Donofrio, Elena Quaglino, Luca Russo, Roberto Ruiu, Federica Riccardo, Francesca Macchi, Valentina Franceschi, Antonino Di Lorenzo, Elisabetta Bolli, Laura Conti
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ff7cb468226493c9a4643b73b30ad77
https://doi.org/10.1158/2326-6066.22544023.v1
https://doi.org/10.1158/2326-6066.22544023.v1