Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Roberto RONCA"'
Autor:
Sara Taranto, Riccardo Castelli, Giuseppe Marseglia, Laura Scalvini, Federica Vacondio, Alessandra Gianoncelli, Giovanni Ribaudo, Jessica Faletti, Giorgia Gazzaroli, Edoardo Rocca, Roberto Ronca, Marco Rusnati, Antonio Sacco, Aldo Maria Roccaro, Marco Presta, Marco Mor, Arianna Giacomini, Silvia Rivara
Publikováno v:
Pharmacological Research, Vol 206, Iss , Pp 107291- (2024)
Fibroblast growth factors (FGFs) act as proangiogenic and mitogenic cytokines in several cancers, including multiple myeloma (MM). Indeed, corrupted FGF autocrine and paracrine secretion induces an aberrant activation of the FGF receptor (FGFR) signa
Externí odkaz:
https://doaj.org/article/f6f8bb6f520c433f84f652679dd1aa27
Autor:
Matilde Monti, Luisa Benerini Gatta, Mattia Bugatti, Irene Pezzali, Sara Picinoli, Marcello Manfredi, Antonio Lavazza, Virginia Vita Vanella, Veronica De Giorgis, Lucia Zanatta, Francesco Missale, Silvia Lonardi, Benedetta Zanetti, Giovanni Bozzoni, Moris Cadei, Andrea Abate, Barbara Vergani, Piera Balzarini, Simonetta Battocchio, Carla Facco, Mario Turri-Zanoni, Paolo Castelnuovo, Piero Nicolai, Ester Fonsatti, Biagio Eugenio Leone, Emilio Marengo, Sandra Sigala, Roberto Ronca, Michela Perego, Davide Lombardi, William Vermi
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-24 (2024)
Abstract Background Mucosal Melanomas (MM) are highly aggressive neoplasms arising from mucosal melanocytes. Current treatments offer a limited survival benefit for patients with advanced MM; moreover, the lack of pre-clinical cellular systems has si
Externí odkaz:
https://doaj.org/article/735a9e3b74ed45228ece9b45b07e75d1
Autor:
Arianna Giacomini, Marta Turati, Elisabetta Grillo, Sara Rezzola, Gaia Cristina Ghedini, Ander Churruca Schuind, Eleonora Foglio, Federica Maccarinelli, Jessica Faletti, Serena Filiberti, Angela Chambery, Mariangela Valletta, Laura Melocchi, Stephanie Gofflot, Barbara Chiavarina, Andrei Turtoi, Marco Presta, Roberto Ronca
Publikováno v:
Experimental Hematology & Oncology, Vol 12, Iss 1, Pp 1-15 (2023)
Abstract Background The pattern recognition receptor long pentraxin-3 (PTX3) plays conflicting roles in cancer by acting as an oncosuppressor or as a pro-tumor mediator depending on tumor context. Triple negative breast cancer (TNBC) represents the m
Externí odkaz:
https://doaj.org/article/ce088ea03fb14b48ad1226cfd227f339
Autor:
Alessandra Loda, Stefano Calza, Arianna Giacomini, Cosetta Ravelli, Adwaid Manu Krishna Chandran, Chiara Tobia, Giovanna Tabellini, Silvia Parolini, Francesco Semeraro, Roberto Ronca, Sara Rezzola
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Cancer stem-like cells (CSCs) are a subpopulation of tumor cells responsible for tumor initiation, metastasis, chemoresistance, and relapse. Recently, CSCs have been identified in Uveal Melanoma (UM), which represents the most com
Externí odkaz:
https://doaj.org/article/cf41dc096c7b48868206c989dbd4bdc0
Autor:
Federica Maccarinelli, Daniela Coltrini, Silvia Mussi, Mattia Bugatti, Marta Turati, Paola Chiodelli, Arianna Giacomini, Floriana De Cillis, Nadia Cattane, Annamaria Cattaneo, Alessia Ligresti, Michela Asperti, Maura Poli, William Vermi, Marco Presta, Roberto Ronca
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract Prostate cancer (PCa) is a leading cause of death in the male population commonly treated with androgen deprivation therapy that often relapses as androgen-independent and aggressive castration-resistant prostate cancer (CRPC). Ferroptosis i
Externí odkaz:
https://doaj.org/article/d2f06106b4a44356b5ea9e86529a1e23
Autor:
Francesco Liguori, Simone Carradori, Roberto Ronca, Sara Rezzola, Serena Filiberti, Fabrizio Carta, Marta Turati, Claudiu T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1857-1869 (2022)
Among the chemotypes studied for selective inhibition of tumour-associated carbonic anhydrases (CAs), SLC-0111, a ureido-bearing benzenesulfonamide CA IX inhibitor, displayed promising antiproliferative effects in cancer cells in vitro and in vivo, b
Externí odkaz:
https://doaj.org/article/ec590cbc66a448ba909f6c31d3ad72a3
Autor:
Marta Turati, Arianna Giacomini, Sara Rezzola, Federica Maccarinelli, Giorgia Gazzaroli, Sonia Valentino, Barbara Bottazzi, Marco Presta, Roberto Ronca
Publikováno v:
Experimental Hematology & Oncology, Vol 11, Iss 1, Pp 1-6 (2022)
Abstract The lymphatic vascular system represents a major route for dissemination of several solid tumors, including melanoma. Even though the members of the Vascular Endothelial Growth Factor family VEGF-C and VEGF-A have been shown to drive tumor l
Externí odkaz:
https://doaj.org/article/cc0101716d6b4c9a8cfab94cd16600c0
Autor:
Silvia Mussi, Sara Rezzola, Paola Chiodelli, Alessio Nocentini, Claudiu T. Supuran, Roberto Ronca
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 280-286 (2022)
Carbonic anhydrase IX/XII (CA IX/XII), are cell-surface enzymes typically expressed by cancer cells as a form of adaptation to hypoxia and acidosis. It has been widely reported that these proteins play pivotal roles in cancer progression fostering ce
Externí odkaz:
https://doaj.org/article/a4629fee4a704236afa8576845ff34dd
Autor:
Ali Mokhtar Mahmoud, Magdalena Kostrzewa, Viviana Marolda, Marianna Cerasuolo, Federica Maccarinelli, Daniela Coltrini, Sara Rezzola, Arianna Giacomini, Maria Pina Mollica, Andrea Motta, Debora Paris, Antonio Zorzano, Vincenzo Di Marzo, Roberto Ronca, Alessia Ligresti
Publikováno v:
Pharmacological Research, Vol 189, Iss , Pp 106683- (2023)
In spite of the huge advancements in both diagnosis and interventions, hormone refractory prostate cancer (HRPC) remains a major hurdle in prostate cancer (PCa). Metabolic reprogramming plays a key role in PCa oncogenesis and resistance. However, the
Externí odkaz:
https://doaj.org/article/08c7a3cef52d4ce7b7827678decc6864
Autor:
Federica Maccarinelli, Mattia Bugatti, Ander Churruca Schuind, Sara Ganzerla, William Vermi, Marco Presta, Roberto Ronca
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Pulmonary fibrosis is a progressive scarring disease of the lungs, characterized by inflammation, fibroblast activation, and deposition of extracellular matrix. The long pentraxin 3 (PTX3) is a member of the pentraxin family with non-redundant functi
Externí odkaz:
https://doaj.org/article/6f5521338d0c4390a1c4ada92dabdd19