Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Roberto R Rosato"'
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 3, Iss C (2014)
Aptamers are a class of small nucleic acid ligands that are composed of RNA or single-stranded DNA oligonucleotides and have high specificity and affinity for their targets. Similar to antibodies, aptamers interact with their targets by recognizing a
Externí odkaz:
https://doaj.org/article/501ea336ef9e496b818fee3155149d27
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99605 (2014)
Methicillin-resistant Staphylococcus aureus (MRSA) is a major multidrug resistant pathogen responsible for several difficult-to-treat infections in humans. Clinical Hetero-resistant (HeR) MRSA strains, mostly associated with persistent infections, ar
Externí odkaz:
https://doaj.org/article/45f1c0d413b94fe4a99621e4964cb93b
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61083 (2013)
The SOS response, a conserved regulatory network in bacteria that is induced in response to DNA damage, has been shown to be associated with the emergence of resistance to antibiotics. Previously, we demonstrated that heterogeneous (HeR) MRSA strains
Externí odkaz:
https://doaj.org/article/737694b2f97549d9849a6d8c280f0948
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71025 (2013)
Methicillin-resistant Staphylococcus aureus (MRSA) has emerged as one of the most important pathogens both in health care and community-onset infections. The prerequisite for methicillin resistance is mecA, which encodes a β-lactam-insensitive penic
Externí odkaz:
https://doaj.org/article/1a17ff9038ed44539d4e696938b8e0be
Autor:
Tejaswini P. Reddy, Roberto R. Rosato, Xiaoxian Li, Stacy Moulder, Helen Piwnica-Worms, Jenny C. Chang
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-11 (2020)
Abstract Metaplastic breast cancer (MpBC) is an exceedingly rare breast cancer variant that is therapeutically challenging and aggressive. MpBC is defined by the histological presence of at least two cellular types, typically epithelial and mesenchym
Externí odkaz:
https://doaj.org/article/fc60bde0ea2e4f0f820084e160ea4cae
Autor:
Tejaswini P. Reddy, Dong S. Choi, Ann C. Anselme, Wei Qian, Wen Chen, Johan Lantto, Ivan D. Horak, Michael Kragh, Jenny C. Chang, Roberto R. Rosato
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-12 (2020)
Abstract Background The human epidermal growth factor receptor (HER) family, notably EGFR, is overexpressed in most triple-negative breast cancer (TNBC) cases and provides cancer cells with compensatory signals that greatly contribute to the survival
Externí odkaz:
https://doaj.org/article/56ecc7c5000b4303a8e6a4a138fe027f
Autor:
Lori J. Goldstein, Raymond P. Perez, Denise Yardley, Linda K. Han, James M. Reuben, Hui Gao, Susan McCanna, Beth Butler, Pier Adelchi Ruffini, Yi Liu, Roberto R. Rosato, Jenny C. Chang
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-9 (2020)
Abstract Background Cancer stem cells (CSCs) are purported to be responsible for tumor initiation, treatment resistance, disease recurrence, and metastasis. CXCR1, one of the receptors for CXCL8, was identified on breast cancer (BC) CSCs. Reparixin,
Externí odkaz:
https://doaj.org/article/ac829d2cdaf14d13a5d03603e1a74bd8
Autor:
Tejal A. Patel, Joe E. Ensor, Sarah L. Creamer, Toniva Boone, Angel A. Rodriguez, Poly A. Niravath, Jorge G. Darcourt, Jane L. Meisel, Xiaoxian Li, Jing Zhao, John G. Kuhn, Roberto R. Rosato, Wei Qian, Anna Belcheva, Mary R. Schwartz, Virginia G. Kaklamani, Jenny C. Chang
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-9 (2019)
Abstract Background Neoadjuvant dual human epidermal growth factor receptor (HER2) blockade with trastuzumab and pertuzumab plus paclitaxel leads to an overall pathologic complete response (pCR) rate of 46%. Dual HER2 blockade with ado-trastuzumab em
Externí odkaz:
https://doaj.org/article/4491401233a240d9afeec8c1bf909d3d
Autor:
Roberto R. Rosato, Daniel Dávila-González, Dong Soon Choi, Wei Qian, Wen Chen, Anthony J. Kozielski, Helen Wong, Bhuvanesh Dave, Jenny C. Chang
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-16 (2018)
Abstract Background Breast cancer has been considered not highly immunogenic, and few patients benefit from current immunotherapies. However, new strategies are aimed at changing this paradigm. In the present study, we examined the in vivo activity o
Externí odkaz:
https://doaj.org/article/82c3a593740f453a94431feea13df07e
Autor:
Sergio Granados-Principal, Jenny C. Chang, Pedro Sánchez-Rovira, Jose A. Lorente, Anil K. Sood, Gabriel Lopez-Berestein, Cristian Rodriguez-Aguayo, Hanna Kim, Cesar L. Ramirez-Tortosa, Maria A. García, Roberto R. Rosato, María Quintana-Romero, David Landeira, Carmen Rosa-Garrido, Rafael J. Luque, María D. Martín-Salvago, Olivier Elemento, Anthony J. Kozielski, Wen Chen, Wei Qian, Alberto Ramírez, Akanksha Verma, Gema Jiménez, Marina Cruz-Lozano, Maria P. Molina, Francisca E. Cara, Juan A. Marchal, Esperanza Muñoz-Muela, Adrián González-González
Supplementary Figure 1. Patient survival with high ATF4 expression in ER+ patients. ROC curve. Differential ATF4 expression induced by TGFβ1 and ERS. SBE motifs in ATF4 promoter and ChiP-Seq analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::539322f9339088f63775a28c8ad9d07c
https://doi.org/10.1158/1078-0432.22470821
https://doi.org/10.1158/1078-0432.22470821
