Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Roberto Pisano"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The nucleation behavior of water is crucial in many fields, spanning meteorology, glaciology, biology, and astrophysics. We report observations suggesting an effect of diffusion kinetics in water on the heterogeneous immersion/contact mode n
Externí odkaz:
https://doaj.org/article/f014bba6c5e147389fbf4272311bbc24
Autor:
Fiora Artusio, Marco Adami, Antonello A. Barresi, Davide Fissore, Maria Chiara Frare, Claudia I. Udrescu, Roberto Pisano
Publikováno v:
Pharmaceutics, Vol 15, Iss 11, p 2570 (2023)
The freeze-drying of biopharmaceuticals is a common strategy to extend their shelf-life and facilitate the distribution of therapeutics. The drying phase is the most demanding one in terms of energy consumption and determines the overall process time
Externí odkaz:
https://doaj.org/article/d2bd4a1140b849629a19c735c8b4fbb7
Autor:
Roberto Pisano, Davide Fissore
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1975 (2023)
Freeze-drying, also known as lyophilization, is a process that facilitates the removal of water through sublimation from a frozen product (primary drying) [...]
Externí odkaz:
https://doaj.org/article/b27464a45db241bb9d19943f84e74898
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 861 (2023)
The measurement of product temperature is one of the methods that can be adopted, especially in the pharmaceutical industry, to monitor the freeze-drying process and to obtain the values of the process parameters required by mathematical models usefu
Externí odkaz:
https://doaj.org/article/55158aca807b4e54ad76b4371b1cb9ea
A proximity-based in silico approach to identify redox-labile disulfide bonds: The example of FVIII.
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0262409 (2022)
Allosteric disulfide bonds permit highly responsive, transient 'switch-like' properties that are ideal for processes like coagulation and inflammation that require rapid and localised responses to damage or injury. Haemophilia A (HA) is a rare bleedi
Externí odkaz:
https://doaj.org/article/f67c08d8d25241749f000a21301cc42b
Autor:
Roberto Pisano, Fiora Artusio, Marco Adami, Antonello A. Barresi, Davide Fissore, Maria Chiara Frare, Francesco Zanetti, Gabriele Zunino
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 635 (2023)
The distribution of biopharmaceuticals often requires either ultra-cold conditions or lyophilisation. In both cases, the drug product is frozen and, thus, exposed to similar stress conditions, which can be detrimental to its quality. However, these s
Externí odkaz:
https://doaj.org/article/7d54cf8ed72c42c9842ccdb0dac8630b
Publikováno v:
Data in Brief, Vol 22, Iss , Pp 722-755 (2019)
A multi-scale approach can be used to simulate the drying behavior of microparticles in packed-bed. Data outcomes from discrete element method (DEM) and computational fluid dynamics (CFD) simulations can be used to estimate some relevant product char
Externí odkaz:
https://doaj.org/article/c7ec8fc1465b41fdb65526ce647a7010
Autor:
Tania Limongi, Francesca Susa, Monica Marini, Marco Allione, Bruno Torre, Roberto Pisano, Enzo di Fabrizio
Publikováno v:
Nanomaterials, Vol 11, Iss 12, p 3391 (2021)
In designing a new drug, considering the preferred route of administration, various requirements must be fulfilled. Active molecules pharmacokinetics should be reliable with a valuable drug profile as well as well-tolerated. Over the past 20 years, n
Externí odkaz:
https://doaj.org/article/c27ed82b61b44c1d8ba58923595bbd6d
Autor:
Elena Lietta, Alessandro Pieri, Elisa Innocenti, Roberto Pisano, Marco Vanni, Antonello A. Barresi
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2135 (2021)
Chromatography is a widely used separation process for purification of biopharmaceuticals that is able to obtain high purities and concentrations. The phenomena that occur during separation, mass transfer and adsorption are quite complex. To better u
Externí odkaz:
https://doaj.org/article/01fe25efd89a4ade92d3ae3ecfa19c5a
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1766 (2021)
Freeze-drying is commonly used to increase the shelf-life of pharmaceuticals and biopharmaceuticals. Freezing represents a crucial phase in the freeze-drying process, as it determines both cycle efficiency and product quality. For this reason, differ
Externí odkaz:
https://doaj.org/article/1c172512c4ca4805bfef4801e4f5469b