Zobrazeno 1 - 10
of 520
pro vyhledávání: '"Roberto Pili"'
Autor:
Christofer Rupert, Carmela Dell’ Aversana, Laura Mosca, Vittorino Montanaro, Davide Arcaniolo, Marco De Sio, Antonio Bilancio, Lucia Altucci, Wulf Palinski, Roberto Pili, Filomena de Nigris
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-19 (2023)
Abstract Background Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cancer. Large-scale metabolomic data have associated metabolic alterations with the pathogenesis and progression of renal carcinoma and have correlated mi
Externí odkaz:
https://doaj.org/article/74f93420daa1482c9b13b147589ffd31
Autor:
Steen Knudsen, Anker Hansen, Marie Foegh, Steen Petersen, Hana Mekonnen, Lin Jia, Preeti Shah, Victoria Martin, Gregory Frykman, Roberto Pili
Publikováno v:
PLoS ONE, Vol 18, Iss 8 (2023)
Purpose Dovitinib is a receptor tyrosine kinase inhibitor of VEGFR1-3, PDGFR, FGFR1/3, c-KIT, FLT3 and topoisomerase 1 and 2. The drug response predictor (DRP) biomarker algorithm or DRP-Dovitinib is being developed as a companion diagnostic to dovit
Externí odkaz:
https://doaj.org/article/959bcf4274864e8ba19888a0ae507918
Autor:
Ricardo A Cordova, Jagannath Misra, Parth H Amin, Anglea J Klunk, Nur P Damayanti, Kenneth R Carlson, Andrew J Elmendorf, Hyeong-Geug Kim, Emily T Mirek, Bennet D Elzey, Marcus J Miller, X Charlie Dong, Liang Cheng, Tracy G Anthony, Roberto Pili, Ronald C Wek, Kirk A Staschke
Publikováno v:
eLife, Vol 11 (2022)
A stress adaptation pathway termed the integrated stress response has been suggested to be active in many cancers including prostate cancer (PCa). Here, we demonstrate that the eIF2 kinase GCN2 is required for sustained growth in androgen-sensitive a
Externí odkaz:
https://doaj.org/article/0e190e2bb8b949968cf1c2d48ee6413b
Autor:
Hayley C. Affronti, Aryn M. Rowsam, Anthony J. Pellerite, Spencer R. Rosario, Mark D. Long, Justine J. Jacobi, Anna Bianchi-Smiraglia, Christoph S. Boerlin, Bryan M. Gillard, Ellen Karasik, Barbara A. Foster, Michael Moser, John H. Wilton, Kristopher Attwood, Mikhail A. Nikiforov, Gissou Azabdaftari, Roberto Pili, James G. Phillips, Robert A. Casero, Dominic J. Smiraglia
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Prostate cancer cells depend on MTAP, the rate-limiting enzyme involved in the methionine salvage pathway, to cope with increased polyamine biosynthesis. Here, the authors show that inducing upregulation of polyamine biosynthesis and targeting MTAP s
Externí odkaz:
https://doaj.org/article/e67ec780a1554759a4b84c3b9ee77ce5
Autor:
Scott I Abrams, Fumito Ito, Yuhao Shi, Melissa Dolan, Jianxin Wang, Xuedan He, Shiqi Zhou, Breandan Quinn, Dushyant Jahagirdar, Wei-Chiao Huang, Moriya Tsuji, Roberto Pili, Joaquin Ortega, John M L Ebos, Jonathan F Lovell
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 12 (2021)
Externí odkaz:
https://doaj.org/article/c3dabdbbc9174f55a2075fc232a9841e
Autor:
Donatella Rita Petretto, Luca Gaviano, Gian Pietro Carrogu, Roberta Berti, Martina Pinna, Roberto Pili
Publikováno v:
Geriatrics, Vol 8, Iss 1, p 5 (2022)
The recent COVID-19 pandemic has led to a sudden increase in the speed of the digitization process, which has affected several areas of life (public administration, schools, universities, and healthcare, and extending to so-called “digital citizens
Externí odkaz:
https://doaj.org/article/7014b20cf8774a058d11525b725f4ec2
Publikováno v:
Asian Journal of Urology, Vol 9, Iss 3, Pp 206-207 (2022)
Externí odkaz:
https://doaj.org/article/27cf1f5b7f9c494c8b5ed4230a4163de
Autor:
Eraldo Francesco Nicotra, Roberto Pili, Luca Gaviano, Gian Pietro Carrogu, Roberta Berti, Paola Grassi, Donatella Rita Petretto
Publikováno v:
Journal of Public Health Research (2021)
In February 2020, Italy has been the first country in Europe fighting against COVID-19. In March 2020, Italian government declared national lockdown. Until May 4th, people stayed in home confinement and only the so-called “essential works and activ
Externí odkaz:
https://doaj.org/article/042915dd13924570998c4bcb2cf01e91
Autor:
Donatella R. Petretto, Roberto Pili
Publikováno v:
Geriatrics, Vol 7, Iss 3, p 55 (2022)
The progressive ageing of the global population is an important anthropological and social phenomenon, and it is due to the overall increasing of life expectancy and the overall increasing of health and living conditions, even if with various trends
Externí odkaz:
https://doaj.org/article/6fbf8f16d59a49038930f2c719e61c0b
Autor:
Li Shen, Roberto Pili
Publikováno v:
OncoImmunology, Vol 8, Iss 10 (2019)
Infiltrating myeloid derived suppressor cells and tumor-associated macrophages (TAMs) are important components of the immunosuppressive tumor microenvironment. We recently reported that tasquinimod, which binds to S100A9, impairs both infiltration an
Externí odkaz:
https://doaj.org/article/0fcb3862a8a249429010c8bbb8ae1f51